Paenibacillus lautus: D5F53_22120
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Entry
D5F53_22120 CDS
T05701
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
plw
Paenibacillus lautus
Pathway
plw00860
Porphyrin metabolism
plw01100
Metabolic pathways
plw01110
Biosynthesis of secondary metabolites
plw01120
Microbial metabolism in diverse environments
plw01240
Biosynthesis of cofactors
Module
plw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
plw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
D5F53_22120 (cobA)
Enzymes [BR:
plw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
D5F53_22120 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
D5F53_22120 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
DAHP_snth_FXD
Motif
Other DBs
NCBI-ProteinID:
AYB45818
UniProt:
A0A385TRS9
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Position
complement(4813640..4815196)
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AA seq
518 aa
AA seq
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MAGKVYLVGAGPGDARLITIKGKECIEKADVVVYDRLASPRLLRWMKPGAEKVYVGKLPD
RHTMKQEQINQLLVDFALEGKTVVRLKGGDPTIFGRVGEEAELLYRHGIMYEIVPGITSA
ISVPAYAGIPVTHRDHASSLSIITGHESPEKLDRMIQWDKVTHATGTLIFMMGVAKIGYI
SHQLMKHGRPPETPVALIRWGTRAEQDTLTGTLADIEDRVMAADFQPPAVIVVGEVVLQR
EHLKWAERLPLFGKRILVTRARSQASSLVSQIEELGGEPYEFPVIETVMPSKGEGLAGIQ
EALDKLATYDWVFFTSVNGVEFFFRHLKEHGRDIRSLASARIVAVGPATADALGNYGIYA
EVIKERYQAEGLIDAYGPELQPGQRVLLPRGDLARRWLPEKLMEMGLHVTEAVIYENVLC
GEDDDELLKLLQDGGIHAVTFTSSSTVTNLLKVLKGMGVAEPADLLKDSTIACIGPLTAQ
TAEEAGLHVSLLAEEATVDSLVKALCVWNENDPRRLTP
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atggcaggcaaggtttatctcgtgggagcaggtccgggcgatgcgcgcctgattacgatc
aaaggcaaggaatgcattgaaaaagcggatgtcgtggtgtatgaccgattagccagtcct
cggctgctgcgctggatgaaacccggagcagagaaggtctacgtaggtaagcttccggat
cggcatacgatgaaacaagaacagatcaatcaactgctggtcgattttgctttggaaggc
aagacggtggtccggttaaagggcggcgatcccacgatcttcggaagagtcggggaagaa
gcggagctgttatatcgtcatggcatcatgtacgagatcgtcccgggaatcacctcggcg
atcagcgtgccggcttatgcaggaattccggtgacgcatcgcgatcatgcctcatcctta
tccatcattacaggacatgaaagccccgagaagctggaccgcatgattcaatgggataag
gtgacccatgcgacggggactttgatttttatgatgggcgtggcgaagatcggttatatc
agccatcagctgatgaagcatggaaggcctccggaaacgccggtggctttaataagatgg
ggaacccgggcggagcaggatacgctgacgggaacgctggcagacatcgaggacagggtc
atggcagcggattttcagccgcctgccgtcatcgtcgttggcgaggtggtgcttcagcgg
gagcacttgaagtgggcggaacggctgcccctgttcggcaaaaggattctggtcacgagg
gcccgaagccaagccagttcgttggtatcccaaatcgaggagcttggcggggagccttat
gagtttcccgtcatcgaaacggtgatgccctcgaagggcgaggggcttgccggaattcaa
gaagcgctggacaagctagctacgtatgattgggtgttcttcaccagcgtaaacggcgtc
gaatttttcttccgccacctgaaggagcatggacgcgatattcgctccttggcctcggca
cgcatcgtcgcggtaggtcccgcaacagccgatgctcttgggaattacggcatatacgcc
gaggtgatcaaggagcgttaccaggcagagggccttatcgatgcttacggtccagagctt
cagccgggccagcgcgtgctgctgcctcgcggcgatctcgcgcgcagatggctgccggag
aagcttatggaaatgggactgcacgtgacggaagccgtgatatacgagaacgtgctgtgc
ggcgaggacgatgatgagctgttgaagctgcttcaagacggcggcattcatgcggtcacg
ttcaccagttcttctacggttaccaatctgctgaaagtgctgaaggggatgggcgtggca
gagcctgccgatctgctgaaggattcgacgattgcttgcatcggaccgctgactgcgcaa
accgcggaggaggccggactgcacgtatcgctcctcgccgaggaagcgacggtcgacagt
ctggtcaaggccttgtgtgtttggaacgagaacgatccacgccgtttaacgccataa
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