Plasmodium malariae: PMUG01_12039900
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Entry
PMUG01_12039900 CDS
T09444
Symbol
DHFS-FPGS
Name
(RefSeq) dihydrofolate synthase/folylpolyglutamate synthase, putative
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pmal
Plasmodium malariae
Pathway
pmal00790
Folate biosynthesis
pmal01100
Metabolic pathways
pmal01240
Biosynthesis of cofactors
Module
pmal_M00841
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pmal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
PMUG01_12039900 (DHFS-FPGS)
Enzymes [BR:
pmal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
PMUG01_12039900 (DHFS-FPGS)
6.3.2.17 tetrahydrofolate synthase
PMUG01_12039900 (DHFS-FPGS)
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GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
39870388
NCBI-ProteinID:
XP_028863080
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Position
12:1402265..1404377
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AA seq
477 aa
AA seq
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MGEEIKSYEECLDKLYKTHAMKLGLDSMKQMSESFNNPTENYKTVHVAGTNGKGSVCYKI
YSCLKLRKFKVGIYSSPHIFSLRERIIVDDEPINEEDLICLVNQVFKKIKEINIYPSFFE
IISLVAFLHFSNKKVDYAIIETGIGGRLDATNILKSPELIIITSIGYDHVHILGSELKDI
CNEKIGIFKKNANVVIGPSVSIYKNVFQKAKELNCTINVVPPEPRGETYNEENSRIAMEA
LKLLKINIDNFLKSVIHIKPPLRKQYLAEEQMQHVKKKFMSTNFLQQNNDYSLYPHAVIL
DVGHNETAIDRLCRDINIFHKGKLIRACISITKPRSLNIFQPLIAQFPHVLKDIFYLPSL
NERTYDFEELVEMINWDNRIKDELKEHVLSGAKKVKQWLRIHRGESADDPTNPNNADNLY
KRGTIPVIVKNAFLECCKDNSILLICGTFFIFDEVLNSFDIYSDMQDTIFMNEPSTI
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgggggaggagataaaaagttatgaggaatgcttagacaaattatataaaactcatgca
atgaaattaggacttgatagcatgaaacagatgagcgagtcgtttaacaatcctactgaa
aattacaaaactgtgcacgttgcaggtactaatggaaaggggtcagtatgctataaaatt
tattcatgtctgaagttgagaaaatttaaggtaggaatatattcttctcctcatatattt
tcactaagagaaagaataatagtagatgacgaaccgataaacgaggaggatttaatatgt
ttagttaaccaagtatttaaaaaaattaaagaaataaatatatatccatccttctttgaa
attatttcactagttgcctttttacacttttcaaataaaaaagttgactatgcaataata
gaaacagggataggtggaagattagatgctacaaatattttgaaaagtcctgaactgatc
ataataacttccataggttatgaccatgtgcatatattaggatccgagcttaaagatata
tgtaatgaaaaaataggtatatttaagaaaaatgcaaatgtagttataggaccatctgtt
tctatatataaaaatgtttttcaaaaagcaaaagaattaaactgcactattaatgtagtg
ccaccagaaccaagaggagaaacatacaatgaagaaaattctagaatagctatggaagca
ttaaaattgttaaagataaatatagacaattttttaaagtcagttatacatattaaacca
ccactacgaaaacaatatttagctgaggagcaaatgcagcatgtaaaaaagaaattcatg
tctacaaatttcctacaacaaaataatgattattctttatatcctcatgctgttatacta
gatgttggacataatgaaaccgccattgatagattgtgtcgagatattaacatctttcat
aaaggaaaattaattagagcatgtatatctataacgaagccacgaagtttaaatatattc
caacccttaattgcgcagtttccgcatgtattgaaggatattttttacttaccgtccttg
aatgaacggacatacgattttgaagagttagtagaaatgataaactgggataatcgcata
aaggatgaattaaaggaacatgttttaagtggagcaaaaaaggtgaaacagtggttgagg
atccatagaggggagagtgcagatgacccaactaacccaaacaacgcggacaatttgtat
aaaaggggtaccattccggtaattgtgaaaaacgcctttctggaatgttgcaaagacaat
tcaattttgctaatttgtggaactttttttatttttgatgaagttttaaattcgtttgat
atatactcagacatgcaagatacaatttttatgaacgaaccatcaacaatttaa
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