Plasmodium malariae: PMUG01_14045500
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Entry
PMUG01_14045500 CDS
T09444
Symbol
PPPK-DHPS
Name
(RefSeq) hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase, putative
KO
K13941
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:
2.7.6.3
2.5.1.15
]
Organism
pmal
Plasmodium malariae
Pathway
pmal00790
Folate biosynthesis
pmal01100
Metabolic pathways
pmal01240
Biosynthesis of cofactors
Module
pmal_M00841
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pmal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
PMUG01_14045500 (PPPK-DHPS)
Enzymes [BR:
pmal01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
PMUG01_14045500 (PPPK-DHPS)
2.7 Transferring phosphorus-containing groups
2.7.6 Diphosphotransferases
2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
PMUG01_14045500 (PPPK-DHPS)
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Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
HPPK
Motif
Other DBs
NCBI-GeneID:
39871766
NCBI-ProteinID:
XP_028864351
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Position
14:complement(1655941..1658589)
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AA seq
651 aa
AA seq
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MAVIEEMTNSRNNMKNIAVLNFGTNDKRNSVTIIETALYLTENSYIYETVPEYIALAEKQ
IVKSVKEVEYESDIKWIKELLSTLGESKYKESDNLIYECNELEKFMKNEKLNENMLKEIS
VHEYELKTKNKLKAQDETMKNNLEKFKNKYYTNYFFNLTVVVRTFIDDPLSMLVIIKYIE
QIMKREDLKDIQRFEKRRIDIDILFFNNYTIFMENLELEKEYIYKVITTYINIDRNNNRH
IEAIERIKNKIQFLSIPHLYTKYRYSILLCLNDIIPNYKHIVLKDTINTLYLNFIRNFKE
TYNINIKEFNRRMYVLKDEVSYLKEKTNIVGILNVNYDSFSDGGLFVNPTKAVERMFEMI
NEGASVIDIGGESSAPYVIPNPSISERDLVIPVLTLFKKKWNEIKYKMKEVDEQNLEKID
RIKPIISIDTVNYNVFKECVENDLVDILNDISACTNNPEIIKLLKKENKFYTVVLMHKRG
NPHTMDKLTDYNDVVYDIKTYLENRLNFLVLNGIPRYRILFDVGLGFAKKHDQSIKLLQD
IHVYDDYPLFIGYSRKRFIAHCMDDHNGVINREKLNFYDDKNDNENDKSKKWLFKVNYMR
KDKDQLPYQKNICGGLAIASYSYYKKVDLIRVHDVLETKAVLDVLTKIHES
NT seq
1956 nt
NT seq
+upstream
nt +downstream
nt
atggctgttatcgaagagatgacaaattctcggaataatatgaagaacatagctgtttta
aatttcggaacaaatgacaaaaggaattctgtaacaattatagaaacagcactgtatttg
acagaaaattcctacatatacgaaaccgtcccggagtacatcgcactagctgaaaagcaa
atagtaaaatccgtgaaagaagtagaatatgaaagtgacattaaatggattaaagaattg
ttaagtacactaggggagtcgaaatataaagagagcgacaatttaatttacgaatgtaat
gaacttgagaaatttatgaaaaatgaaaaattaaatgagaatatgttgaaagaaattagt
gtgcatgaatatgaattgaaaactaaaaataaattaaaagcgcaagatgaaacaatgaaa
aataatctggagaaatttaaaaataaatattacacgaattatttttttaatttaactgtt
gtggttagaacttttattgatgacccacttagcatgttagtaattataaaatatatagag
cagataatgaaaagggaagatttaaaagatatacaaagatttgaaaaacgtaggatagac
atagatattttattttttaataactataccatttttatggaaaatttagaattagaaaaa
gaatatatatacaaagttatcacaacatatattaacattgacaggaataacaatagacac
attgaagcaattgaaagaataaaaaataagatacaatttctaagtattcctcatttatac
acaaaatatagatatagcatattattatgtttaaatgatataatacctaattataaacat
attgtattaaaagatacgataaacacattgtatttgaattttattagaaattttaaagag
acatataatataaatatcaaggagtttaatagaagaatgtatgtattaaaagatgaggta
tcttatttaaaggagaaaacaaatatagttggtatattaaatgtaaattatgattctttt
tctgatggaggtttatttgttaatccaaccaaagctgtggaaagaatgtttgaaatgata
aatgaaggggcaagtgtaatagatataggaggagagtcgtctgctccttatgttattcca
aatcctagtattagtgaaagagatttagttatacccgttttaacattatttaaaaaaaaa
tggaacgaaataaaatacaaaatgaaagaagtagatgaacagaatttagaaaaaatagac
agaataaaaccgataataagtattgatacggtaaattataatgtttttaaagagtgtgtt
gaaaatgatttagttgatattttaaatgacattagcgcatgcacaaataacccagaaata
ataaaattattaaaaaaagaaaataaattttacactgttgttttaatgcataaaagggga
aatccacatacaatggataagttaacagattataatgatgttgtttatgatattaaaact
tatttagaaaatagattaaattttcttgttttaaatggaatacctcgttatagaatatta
tttgatgtaggtttaggatttgcaaaaaagcatgatcagtcaattaaactgttacaggat
attcatgtttatgatgactatcctcttttcattggttattcaagaaaaagatttattgca
cattgtatggatgatcacaatggtgtaataaatagggagaaattgaatttttatgatgat
aaaaatgacaatgaaaatgataaatcgaaaaaatggttgtttaaggtgaactacatgcgc
aaggataaagaccagctgccatatcagaaaaatatatgtggaggattagccattgcctcg
tacagttattacaagaaggtagacttaataagggttcatgacgtactagaaactaaggca
gttttagatgtacttacaaaaatacacgaatcgtaa
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