Panthera pardus (leopard): 109263406 Help Entry 109263406         CDS       T06062                                  Symbol MDN1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism ppad  Panthera pardus (leopard) Pathway ppad03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:ppad00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     109263406 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:ppad03009]     109263406 (MDN1) Ribosome biogenesis [BR:ppad03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     109263406 (MDN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA_16 AAA AAA_3 AAA_22 AAA_7 TsaE nSTAND3 Sigma54_activ_2 Sigma54_activat AAA_14 AAA_18 ABC_tran AAA_6 MDN1_4th AAA_2 DUF815 Dynein_heavy AAA_25 PduV-EutP ResIII Pus10_N_euk Motif Other DBs NCBI-GeneID:  109263406 NCBI-ProteinID:  XP_019298392 Ensembl:  ENSPPRG00000007843 LinkDB All DBs Position Unknown AA seq 5604 aa AA seqDB search MTAGGGGSAVMEHLFLEVAAAPLRLLAAKNEKSRSELGRFLAKQVWTPQDRQCILSTLAQ LLLDKDCTVLVGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLICNHPDVLP FALRYFKDTSPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAYKFLQNEQSVFRELWDWS VCVPLLRSHDTLVRWYTANCLALVTCMNEEHKLSFLKKIFNSEELIHFRLRLLEEAQLQD LEKALVLANPEASLWRKEKELQYLQGHLVSADLSARVTAVCGVVLPGQPPAPGEQASNRS SSREQELAFRSYVLVDSICKNLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLGAMTGRRK PPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATKGHWILLEDIDYAPLDV VSVLIPLLENGELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHAALLDKYWTK IHMDNMDKKELNEVLQNRYPSLLAVTDHLLDIYIQITGEKHHSQNDSSVTCEQAPEEVSE ARRENKGLSLEGRELSLRDLLNWCNRIVHSFDSLSSSASLNIFQEALDCFTAMLSKHTSK LKMAEVIGSKLNISKKKAEFFCQLYKPEIVINELDVQVGRVRLLRKQSEAVHIQREKFTF APTRPSSILIEQLAVCVSKGEPVLLVGETGTGKTSTVQYLAHITGHHLRVVNMNQQSDTA DLLGGYKPVDHKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQH VHKSAVNKDGKESETGLLLKEKWEAFGLRLSHAQQQMKMTENALLFAFVEGTLAQAVKKG EWILLDEINLAAPETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVG KRNLPPGIRNRFTELYVEELESKEDLQILIVDYLKGLSVNKITVQGIINLYTALRKDSGT KLVDGTGHRPHYSLRTLCRALRFAASNPCSNIQRSLYEGFCLGFLTQLDRASHPVVQKLI CQHLISGSVKSLLKQPIPEPKGGRLIQVEGYWISVGDREPTIDETYILTSSVKLNLRDIV RVVSAGTYPVLIQGETSVGKTSLIRWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGK LVFKEGILIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLITETQEVVKAHPRFM LFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVM LDLQSYRRSSSVFAGKQGFITLRDLFRWAERYRLAEQTEKEYDWLQHLANDGFMLLAGRV RKQEEIDVIQEVIEKHFKKKLCPQSLFSKENVLKLLSKLSTRVSMLESEFSHIVWTEGMR RLVMLVGRALEFGEPVLLVGDTGCGKTTVCQMFAGLANQKLYSVNCHLHMETSDFLGGLR PVRQKPKDKEEIDTSRLFEWHDGPLVLAMKEDGFFLLDEISLADDSVLERLNSVLEVEKS LVLAEKGSVEDKDNEVELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTG REDLIQIISHNLRPGLSLGKVDHKGADIAKVMLDFIEWLTHQEFGRRCVVSIRDILSWVN FMNTMEEEAALKRPETISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIE KLSKIVRLTECQKNELKIYDRLKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAG TTAMNAQRLLRATKLNKPILLEGSPGVGKTSLVTALAKASGNILVRINLSEQTDITDLFG ADLPVEGGKGGEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPE LGMSFQVQHEKTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVVDMEFIASTLFP AIDKNIVKKMVAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPG QHVFLVYGERMRTKEDKEKVIAVFKNVFSSDSSPYMGTRLFHITPYDVQLGYSVLSRGSY APLLSRHPLSLLHQSLQSLESVMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIM AMNSAMDTTELLGGFEQVDLIRPWRQLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHF LLTYKPKCLGDGGRGITMEIVNKLEAVLLLMQRLNNKINSYSKAEFAKLVEEFRNFGAKL LQSTSGRSHGTFEWVDSMLVRALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISER GMIDGSTPTITPNPNFRLFLSMDPVHGEISRAMRNRGLEIYISGEGDGNIPDNLDLKVLL HSLGLVGDSVCDTLLALHMEIQSTVVGSPTSSISTLIQTALLIVQCLQRGLSLDTAFSEV CWEAYVRSQHSPANQKLVQSLLEKHIFSLRAHETWGNSILAMGLWPDSLPSAIFATEDSH LSRVRSDGQVLVYCLNRMSMKTSSWARIQPLTLPDLEKIMQSSNPESLKFSSIEVATSWI DEPDVLAMAVKLLIERATNQDWVLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSN SLSAGVSNVIKILQPNITDEFVIPLDPRWNIQALDIIRNSMDFDPQTDQPEQLFALLESV ANKTIIYLDREKRIFTEANLVSVGGKKLRNSVLRMSFEFHKDPESYHSLPHEIVVNLAAF FELGDALILLWVQSSQGMVSDVSVMEILDSLRWRDRFWTIADTVKVDASGLALLALHWHW VLKHLVRQIPQLLMNHEDKYYKEVQTVSEHIQNCLGSPTGGFTGVKKLQKFLGRPFPFKN KLVVECFSQLKVLNKALAMREWMPALGEGGWWEDVNRLQVVASKWTLKKSLLQAWGLVLR ANILEDVNPDELKDLVNAHCLELKAKGISLGFLEKKHNEASSLFQPDFTSLIQLTRSVQL WPAMEYLALLWQYKVTADFMTQACLRRSSKNQQPQTDQERSPHILFCLKHTPIAPQELQA FWYLLHHQKVSTEEIISLWSDLFNSTFMSFWSSTVTTNPEYWLMWSPLPGVQQREMPKSL LDSTLKGPGSLSRAIFSKCCFEVLTSSCRASPWDVSGLPILSSSHVTLGEWVERAQQLRD ISLVLWTNMAVPSVAEFRYTDSQLQRLVLCRHLAGLAELLPESRRQEYMQNCEQLLLRDK QTFQHVGQTLGDMAGQEALPKELLCLLLTSLRHLFGEGDGKRDLPEPARRGSLWVSLGLL QIQTWLPQARFDPAVKREYKLKYAKEELHQLQCEWKTRNLSSQLHTGRDLEDEVILSYCH PHIRLLRQRIDHLENLICSLSKKQAFRPQVPAYESLVQEIHHYVTSIAKAPAVQDLLTRL LQALHMDGPRSAQVAQNLLKEEASWQQSHHQFRKRLAEEYALYPDSVAPLQASILQLQHG MRLVASEVYASFHGSVVCADRLGAMATSLLAFPSVGPTFPTYYAHADALCSVKSEEVLRG LGKLILKRSGGKELEGKGQRPCPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQE IINEWDEQERIAQEKAEEENSLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILV EPTLEEKKGTSDGQEEGAASDPGLLSQSSMQAVMLIHQQLCLNFARSLWYQQTLPPHETK HYLGLFLSCYQTGASLVTQFYPLMGAELNDQLLGSQLLACTLSHNTLFGEATSDLIMKPD GPYDFYQHPNVPEARHCQPVLQGFSEAVSQLLQDWPEHPALEQLLVVIDRIRSFPLSSPI SKLLNGLEILLAKAQDWEENASRALSLRKHLDLVSQTIIRWRKLELNCWSMSLDNTMKRH TEKSTKHWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQML LVFHCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISK WNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLSQPVATSEA SPIQSLNMALRETLLAQPVAAQAVIPEQCQGASFPLEGELLCRLPKLMKRMRKVCLTLMK ESRLPYLVEGLDHFTGEVISSVRELQSLNVEPSAEKEKQRSEAKHILLQKQRALADLFQH LAKTGLSYRKGLAWARSKNPQEMLHLHPLDLRSALSVVSSTQADSRLLTEISSSWDGCQK YFFRSLARHARLSAALAAPAKELGMSNVERCKGFSAHLMKVLIQQRRSLTTLTEQWILLR NLLGCVQEIHGRLTEPLVYPVAFPPQDGVQQWTERLQHLAMQSQILLEQLSLLLQCCPSA GPTPGHSGAQVQGQPSAPYPEGPELTNGQLSGAIQDLIPSEFSCPSPLPRNQLPSGCWMR KQDELWQQSTARLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSGLSCLSQVSV HLQGLESLFIIPRIEVEQTDQQMALVESLDYLRGEINKATDDFTSWKTHLLASGSQSGNQ MLDEGFVEDFSEQVETAIRAILCAIQNLAERNSKKTEENTDQSRPQEEDGAAGLEGLQSG HLTKLLEDDLWADVSTLHVQKIISAVSELLERLKSYGEDGTAAKHTFFSQSCCLLVRLVP MLSRYSDLVLFFLTMSLATHRSTAKLLSVLAHVFTELAQEGFCLPKEFMEDSAGEGATEF HDYEGGGIGEGEGMKDVSDQIENEEQAEDTLQKGQEKDKEDPDSKPDIKGEDNAIEMSED FDGKMHDGELEKEEDDGKSDSEGGDLDKQMGDLNGEEADKLDERLWGDDDDEEEEDSKTE ETGPGMDEEDCGLVAKDDNLDAGKSNRDKNRDKEEKEEAEVADDRQGQDKINEQIDEREY DENEVDPYHGNQEELPEPEALDLPDDLNLDSEDKNGSEDTDQEEGEDNPLEIKEKPMDTE EAGHEAEEIKEQTEADHSEGQGQPEPEEGPSEDDKGEGEEEMDTGADDQDKDTAEHPEEN SDDERQSLEDKDKEANEESADNGVPVDQGLQPQKEEEEEEGSGENSDTEEQVPEATEREE HDSCGQTGVESVQSAQAMELAGAAPEKEQGKEEHGSGAADANQAEGHQSNFIARLASQKQ TRKDTQSFKRKPGQADNERSMGDHNERVHKRLRTVDMESHTEQGPAQPHAQVEDADAFEH IKQGSDPYDAQTYDVASKEQQQSAKDSSRGQEEEMEDTFMDTEEEELQAADTEQLKPEEI KSGTTVSPGYDEVDMETHTVRTEEDQDPRTDISQGETEDMKPERSQDSTIHTAHQFLVDT IFQPILKDVSELRQELERQLETWHPHESGNPEEEKAAVQMWQSYLAVTAPLSQQLCEQLR LILEPTQAAKLKGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDS SSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDFSGSQILR LCKFQQKKTKIAQFLESVASMFAAAQQPSQHASPENAQLLLVVSDGRGLFLEGKDRVLAA VQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDV NALPETLSDALRQWFELVAASDHL NT seq 16815 nt NT seq  +upstreamnt  +downstreamnt atgaccgccgggggcggagggtctgcggtcatggagcaccttttcctagaggtggcggcc gcgccgctgcgcttactcgctgccaagaacgagaagagccgcagcgaactgggcaggttc ttggccaagcaggtgtggacacctcaagatcgccagtgtatcctgagcaccttagcacaa ttacttctggataaagactgtactgtgctggttggtcgccagctgcgccctcttcttttg gatttgttggaaaggaatgctgaagccattaaagccggaggccaaatcaaccacgatcta cacgaacggctctgtgtgtcaatgagcaaactcatttgtaaccatcctgacgtcctcccg tttgccctgaggtatttcaaggacacttctccagtcttccaaagactcttcctagagagt tcagatgctaatccagtccgctatgggcgcaggcggatgaagctccgggacctaatggaa gcagcttacaagtttctgcagaacgagcagtctgtgttccgggagctctgggactggagt gtgtgtgtccctctcctcagaagccatgacaccttggtccgctggtacacagccaattgt cttgctttggtcacctgtatgaatgaagagcacaagttatcattccttaagaagattttt aatagtgaggaactgatccatttcaggttaaggttattagaagaggcccagctgcaggac ttggagaaggccttggttttggctaatccagaagcctccctttggcgtaaggagaaagag ctgcagtacttacagggccatcttgtttcagctgatctctctgccagggtgactgctgtc tgtggcgtggtgctgcctgggcagccaccagcccctggagagcaggctagtaacagaagt tcttctcgtgaacaggagctggcctttaggtcttatgtgctggttgattcaatctgcaaa aatcttcagacgctggctatggcagtggcttctcagaatgctgtgttgttggaaggaccg ataggatgtggcaaaacttccttagttgaatacttaggtgcaatgacgggtagaaggaag ccccctcagcttcttaaagtccagcttggagatcagaccgacagtaagatgctgttggga atgtatcgctgcacagatgtcccgggagagtttgtgtggcaacctggtaccctgacacag gcagccacaaagggacactggatccttctggaggatattgactatgcccctttagatgtg gtttctgtgctgatccctctcttggagaacggagagctcttgattcccggccgaggtgac tgtctgaaagtggctcctggatttcagttctttgcaactaggagactcttgagctgtgga ggaaattggtatcgacctctaaatagtcatgctgctctgctagacaaatattggaccaaa attcacatggataacatggataagaaagaactgaatgaggttcttcagaacagatatccc agcctcttggcagtaactgatcacttgcttgacatttacatccaaattactggagagaaa catcactctcagaatgatagttctgttacatgtgaacaggcacctgaggaagtttcagaa gccagaagagaaaacaaaggactaagccttgagggaagagagttgtctctaagggatcta ctgaattggtgtaataggatcgttcatagctttgacagtctgtcttcatcagcatcctta aatatttttcaagaggctctggactgtttcacagcaatgctttctaagcatacaagcaaa ctgaaaatggcagaagtcattggaagcaaattgaacatttccaagaaaaaggctgaattt ttctgtcaactttataaaccggaaattgtgatcaatgagttagatgtgcaagtgggtcga gtgcggcttcttcggaaacaaagtgaggctgtccacatacagagggagaagttcactttt gctcccacaaggccatcctccattcttattgaacagcttgcagtgtgtgttagcaaaggg gaaccggtattgctggtgggagagactgggactggcaaaacctctactgtccagtacttg gctcacattacaggccaccatttgagggttgtcaatatgaatcaacaaagtgacactgca gacttgcttggaggttacaaaccagtggaccataaacttatttggctgcccttacgggag gcatttgaagaactctttgcccagacattttccaagaagcaaaactttacattcttagga cacattcagacctgttacaggcagaaacggtggcatgatctcctcagactaatgcagcat gtacacaagtcggccgtcaacaaggatggaaaagaaagtgaaactgggttactcctaaaa gagaaatgggaggcatttggtcttagactcagccatgctcagcaacagatgaaaatgact gaaaatgccctcttgtttgcattcgtagagggtacactagctcaagccgtaaagaaagga gagtggatcttattggatgagattaatctggctgctccggaaacattagaatgtctcagt ggtttactcgaaggctcctctggctcactggtgttgctagatcgaggagatacagaacca ctggttcgtcatcccgacttccgtttatttgcctgtatgaacccagcaacagatgtgggc aaaaggaatcttccaccaggaataagaaacaggttcacagaactttatgtagaagaattg gaaagtaaagaagatttacagattcttattgtggattatctgaaaggactgagtgtgaat aagatcacagtgcaaggaattatcaacttgtacacagctctacggaaagactctgggaca aaattagtggatggaactggccatagacctcactacagccttcggactctttgcagggcc ctgcgatttgcagcctccaatccgtgtagcaacatccagcgctcactctatgagggcttt tgtttgggtttcttaacacagcttgatagggcatcacatccagtagttcagaagctcatt tgtcaacaccttatctctggcagtgtaaaaagtctgctgaagcagcctattccagaacca aaaggaggtcgtcttatccaagtcgaaggatactggatttcggtgggagacagggaacct acaatagatgagacctacattcttacgtcttctgttaagctaaacctgagagacatagtc cgagtggtttctgcaggaacctatccagtgttgattcagggagagacatcagttggtaaa acaagcctgatccggtggctggcagcagctactggtaaccattgtgtgcgtattaacaat cacgaacacacagatattcaggagtatattggttgttacacatctgactcttcagggaag cttgtgtttaaagaaggtattcttattgatgctatgagaaagggctattggattatttta gatgaattaaatttggcccctaccgatgtgttagaggcactgaacagattactggatgat aaccgtgaattgctcatcacagaaacacaagaagttgttaaagctcaccctcggttcatg ctttttgctacccaaaatcccccaggactttatggaggcagaaaggtgctttctagagcc ttcaggaatcggtttgtggagctgcattttgatgaactgcctagttctgagctggagaca atcttgcataaacgctgtagtttgccaccctcctattgtagcaagttggttaaagtcatg ctggaccttcagtcctatcgcagaagttcttcagtgtttgctggaaaacagggcttcatc acccttcgtgatctgtttcgatgggctgaaagatacagattggctgaacagactgagaaa gagtatgactggctacagcatttagccaatgatggttttatgctgctcgcaggccgagtc aggaagcaggaggaaattgatgtgattcaagaagttattgaaaaacattttaagaaaaaa ttgtgtcctcaatcccttttctccaaagaaaatgtcttaaaattactgagtaaattgtcc actcgggtatccatgttggaatctgagttcagccacattgtgtggactgagggcatgcgg agactggtgatgctggtaggaagggcgctggaatttggtgaaccagtgctactggttggg gacactgggtgtgggaaaactactgtctgtcagatgtttgcaggcttggcaaatcagaaa ctatactctgttaactgccacttacacatggagacatcggatttcctgggagggctgcga ccagtgagacagaagccaaaggacaaggaagaaattgatacatcaaggctttttgagtgg catgatggtcctctagttctggccatgaaggaggatggcttttttctcttggatgaaatc tcactggctgacgactctgttctggaaagactcaatagtgtccttgaagtggaaaagtcc ttggtattagctgaaaaaggcagtgtagaagacaaggataatgaggtagagctgttgact gctgggaagaaattccgtatcttagcaaccatgaaccctgggggcgactttggaaaaaaa gagttgtctcctgccttaagaaacaggtttacagaaatatggtgcccacaaagcacaggt cgtgaagatttaattcagattatcagccataaccttcgtccaggattgtctctgggcaaa gtagatcataaaggggctgacatagctaaggtgatgctggatttcattgaatggctgacc caccaggaatttggccgaaggtgtgtggtcagtatcagagatatcctgtcctgggttaac ttcatgaacacaatggaggaggaagctgctttgaaacggccagagaccatctccactgtg acatcttttgtccatgctgcatgcctggtgtacatagatggaataggttcaggggtaact tcctcagggtttggtacagctctcttggctcgcaaagaatgtctgaaattcctaatcgag aaactttccaaaatagtgagacttacagagtgtcagaaaaatgaattgaagatttatgac agactcaaggccaaagaatttactggaatagataacctttggggaattcatccatttttt ataccaaggggacctgtccttcacaggaataatattgctgactatgcactcagtgcaggc accactgctatgaatgcccagaggctcttaagagctacaaaattgaataaacccattctc ctggagggctctcctggtgtgggcaagacaagtttggtgacagcattagcaaaggcttca ggcaacatccttgttcgaatcaacttgtcagaacagacggacatcacagacctgtttgga gcagatctacctgttgaaggtggcaagggaggagagtttgcctggcgggatggccctttg ctggcggccctgaaggcaggccattgggttgtgttggatgagctcaacctggcttctcag tctgtattggaaggactcaatgcttgttttgaccaccgaggagaaatttatgttcctgag ttaggaatgagctttcaagtacagcatgaaaagacgaagatttttgggtgtcagaatccc tttagacaaggaggtgggaggaagggcttgccaagatctttccttaacagattcactcag gtctttgtggatccccttacagtagttgacatggaattcattgccagtactctgtttcca gccattgacaaaaatattgttaagaagatggttgctttcaacaaccaaattgatcacgaa gtgactgttgaaaagaaatgggggcaaaaaggaggaccctgggaattcaaccttcgggac cttttccgctggtgtcagttgatgctagttgaccagtcccctgggtgttatgatcctggt cagcatgtgtttttggtctatggtgaaagaatgagaaccaaggaagacaaggaaaaggtc attgctgtattcaagaatgtgtttagttcagattccagcccatacatgggaaccagacta tttcatatcactccctatgatgttcagctgggctactcagtcctctcccgtggcagttac gctcctctcttgtctcgccatccactgtcactcctgcaccaatcactacagtctctggag tcagttatgaagtgtgtgcagatgagctggatggtcatccttgtggggccagcctctgtg ggcaagaccagcctggtgcagctcctggcacaccttactggtcacacgttaaagatcatg gctatgaacagtgcaatggacactacggagcttctaggtggatttgagcaggttgatctt atacggccatggaggcagctgctagaaaaggtggaaggcactgtaagggcacttttaaga gacagcctccttatcagtgctgacgacgcagaagtagtgctgcgagcctggagtcatttc cttctgacttacaaacccaagtgtcttggagatggtggtagaggtatcacgatggagatt gtcaacaagctggaagcagtattattgcttatgcagagactcaacaataaaatcaactcc tactccaaggcagagtttgccaaacttgtggaagaattccgaaattttggggcgaagctt ctgcaatccaccagtggtcgcagccatggcacatttgaatgggttgacagcatgttggtt cgggctctgaagtctggagattggcttttgatggacaatgttaacttctgcaacccatca gtcctggatcgtttgaatgctttgctggaacctggaggtgttctcactattagtgaaaga ggaatgatagatggatccactcccaccataacaccaaatcccaatttcagactttttctc tcgatggatcctgttcatggagaaatatcccgagcgatgaggaatcgtggacttgaaatc tacatttcaggagaaggggatgggaacatcccagataacctggatctgaaagttctcctg cacagccttggattggtgggggacagtgtgtgtgacaccctcttggctctacacatggag atccagagtactgttgtaggttctccaacatcatctatttcaactttaattcagacagcc ttactcattgtgcagtgcctacagcgagggctgagtttagacacagccttttctgaagta tgctgggaagcatatgtccgctcccagcattcaccagcaaaccaaaagcttgtgcagtct ttactggagaaacatattttttctctacgagcccatgaaacctggggtaactccatcctt gccatgggcctgtggccagattctctgccctcagcaatctttgctacagaagattctcac ctctctagagtccgaagtgatggacaagtcttagtatattgccttaacaggatgagcatg aaaaccagcagctgggccaggattcagcctcttaccttaccagacttggagaaaattatg cagtcctctaaccctgagagcttgaaattcagttcaatcgaagtggctacttcctggatt gatgaaccagatgttctggccatggctgttaaattgcttatagaaagagcaaccaatcaa gattgggtgctcagagttaaatggctttatcatttagccaagaatataccacaggggctt gaatcaatacagattcatttggaagccagtgctgcatcacttaggaatttttactcaaat tctctctcagctggggtcagtaatgtcatcaaaatattacaaccaaatataacagatgaa tttgtgatccctttggacccccggtggaatatacaggctttggacatcattagaaattcg atggactttgacccacaaaccgatcagcctgagcagctttttgcccttttagagtctgtt gcaaacaagacaatcatatatcttgaccgggaaaaacggatatttactgaagcaaatttg gtttctgttggtggcaaaaagttaagaaatagtgttttgagaatgtcctttgaattccat aaagatccagagagctatcacagcctgccccatgaaattgtggtcaatcttgctgctttt tttgaacttggtgatgcactaatcctgctctgggtacagtcctcccaggggatggtgtct gatgtcagtgtcatggagatcttggattccctgcggtggcgggaccggttttggaccata gctgacacagtaaaagtggatgcctcaggcctggccctgctcgcccttcattggcactgg gttttaaaacatctggtccgtcagatccctcaactcctaatgaaccatgaagacaaatac tacaaagaggttcagactgtctcagaacatattcagaattgcttggggagcccaactggt ggcttcactggtgtaaagaagttgcaaaagttcctgggacggccatttccttttaagaac aagctggtggtagagtgtttttctcaattgaaagtacttaacaaagcacttgccatgagg gagtggatgcctgcccttggggaaggcggatggtgggaagacgttaatcgtctccaagtg gttgcttctaaatggactttaaagaaaagtctcttgcaggcgtgggggctggtcctcaga gctaatattctggaagatgtcaacccagatgagctgaaggatcttgtgaatgctcactgt ttagaactaaaagccaaaggaatttcacttggttttctggagaaaaagcacaatgaagct tcctccctgttccaaccagactttacctccttaatccaactcaccaggagtgttcagttg tggcctgcaatggagtacctggctctgctttggcagtacaaagtgacagctgattttatg acacaagcttgcctaagaaggtccagcaaaaatcagcaaccccagacagatcaggagaga agtcctcacatcctattttgtcttaagcacacaccaattgctccacaagagcttcaagcc ttttggtacttactgcaccatcagaaggtgtctactgaagaaattatttccttgtggtct gacttatttaattccacatttatgtctttctggagcagtactgttactacaaatccagag tactggctaatgtggagccctctgcctggtgtacagcagagggagatgcccaagtccctt ttggactccacattgaagggccctggcagtctcagtagagccatcttctccaagtgctgc tttgaagtattgaccagcagctgcagagcaagtccctgggatgtgagcggcctccccatc ctgtcctcctcacatgtcaccctgggagagtgggttgagagagcccagcagctccgggat atcagcttggtgctttggaccaacatggctgtgccttcagtcgcagagttcagatacacg gattcccagctccagagacttgtgctgtgccggcacttggcgggtttggcagagctgctc cctgaatcccggcggcaggaatacatgcaaaactgtgagcagctgctgctcagggacaag cagaccttccagcatgtgggccagactcttggggacatggccgggcaggaggccctgccc aaagagctgctatgcctgttgcttacctccctgcgccacttgtttggggaaggggatggt aagcgggacctgcccgagccagcacggcgtgggagcctgtgggtgagccttggcttgctc cagattcagacatggcttccacaggcccgctttgaccccgcagtgaagagggaatacaag ctcaagtacgctaaggaagagttacaccagctgcagtgtgagtggaagacccgaaacctc tcatcccagctacacactggaagagacctggaagatgaagtcattctcagttactgtcat cctcacatcagattacttcgccaaagaatagatcatctggagaacttaatctgcagcctg tcgaagaagcaggccttcagaccccaggtgcctgcctatgagtcattggtgcaggaaatc caccactatgtcaccagcattgccaaggcccctgctgttcaggatctgctcacacggctc ctgcaggctctccacatggatgggcctcggtctgcccaggtggcccaaaaccttctgaag gaggaggcttcctggcagcagtcacaccaccagttcaggaagcggttggccgaggagtat gccctctatccagattctgtggccccactgcaggcatccatcttgcagttgcagcatggc atgaggctggtggcatctgaggtctacgcttcattccatggcagtgtggtctgtgcagac aggctgggtgccatggccacatccctgttggcttttccatcagtgggccccaccttcccc acttactatgctcatgcagacgccttatgctcagtgaagtcagaggaggttcttcgaggc cttgggaagttgatcctcaagcgctcaggaggaaaggagctggaaggcaagggccagaga ccttgtcctacccgagagcagctgctgatgaatgccctcctttacctgcgttcccatgtg ctgtgcaagggagagctggaccagagggccctgcagctcttcaggcatgtgtgccaggaa attatcaatgagtgggatgaacaggaacgcatagcccaagagaaggctgaggaggaaaac agcttgtacagatacaggagcaggaactccaggactgccctgagcgaggaggaggaggaa gaacgggagttcagaaagcagttcccactgcatgaaaaggattttgcagatattttggta gaaccaacactggaggagaagaagggaacttcagatgggcaagaagagggagcagcttca gatcctggcctcctctcccagagctcaatgcaggctgtgatgctcattcatcagcagctg tgcctcaactttgctcggtccctctggtaccaacagactttgccaccacatgagacaaag cattaccttggcctgtttctatcctgctatcaaactggggcatctcttgtgacacagttc taccctctgatgggagctgaactgaatgaccaactcctgggcagccaacttttggcctgt accctctcccataacactctctttggtgaggcaacctcagatctgataatgaagcctgat gggccctatgacttctaccagcaccccaatgtcccagaagcaaggcattgtcaacctgtg cttcagggtttctcagaggctgtcagtcagctgctgcaggattggccggaacacccagcc cttgagcagctgctggttgtaatagacagaattcgtagtttcccactttccagtcctatc tcaaagttgctgaatggcttagagatccttctagcaaaggcacaggattgggaggagaat gcaagtcgagctctgtctctgcggaaacatctcgatttagtcagtcagacgatcattcgt tggcgtaaactggaactgaactgctggtctatgagtttggataataccatgaagcgccat actgagaaatccaccaagcactggttctccatctaccagatgcttgagaagcacatgcag gaacaaacagaggagcaggaagatgataagcagatgaccctgatgttgctggtcagcaca ttacaagcatttattgagggatcctcactgggagaattccacgtacggcttcagatgtta ctggttttccattgtcatgtcttgttgatgcctcaagttgaaggaaaggattcactttgc agtgttctgtggaatttgtaccattattacaagcaattctttgaccgggtccaagccaaa attgtggaacttcgttcccccctagaaaaagaacttaaagaatttgtaaagatatccaag tggaatgatgtcagcttctggtccattaaacaatctgtggaaaagacacacaggaccctc tttaaattcatgaagaaatttgaagctgtcctgagtgaaccctgccggtcatccttggtg gagagtgacaaggaggaacagcctgactttttgtcacagccagtagccaccagcgaggca tcccccattcagagtctgaacatggcactgagggagaccctgttggcccagccagtagct gcacaggctgtgattccagaacagtgtcagggtgcttctttccccttggagggagagctg ctgtgtcgcttgccaaagctcatgaaacgaatgaggaaggtgtgcctgacgctcatgaag gaaagccgtctgccttacctagtggagggccttgatcacttcactggtgaagtgatttcc tctgtgagggagctgcagagcttgaatgtggagccctctgcagagaaggagaagcagcgg tcagaagccaagcatattctcctgcagaagcagcgagctttagcagacctctttcaacac cttgccaaaactggtttgtcatatcgcaaaggtcttgcctgggcccgttcaaaaaaccct caagagatgcttcatcttcacccgttagatctccggagtgcattgtctgtagtcagcagc actcaggctgattctaggctgctgacagaaatctcctcttcatgggatggatgccagaag tacttctttcgctctcttgcacggcacgccaggcttagtgcagccttagcagctcctgcc aaggagttgggcatgagcaacgtcgagcgatgcaaagggttctcggcacatctgatgaag gtgcttatccaacagcggcgctccctgaccacgctgactgagcagtggatcctcctcagg aacctccttggctgtgtgcaggagattcatggcagactgactgagccgctggtctacccg gtggccttcccccctcaggatggtgtgcagcagtggacagaaaggctgcagcatctggcc atgcagagccagatcctgcttgagcagctctccttgctcctccagtgctgccccagtgca gggccaactccaggccacagtggtgcccaggtacagggtcagccttctgccccctaccca gaaggaccagagctcaccaatggccagctttctggagccatacaggacctcatcccatca gaatttagttgcccatccccactacctcgaaatcagctgccctctggttgctggatgcgg aaacaggacgagctttggcaacagtcaactgcgagattaacagagatgctgaaaaccatt aaaacagtgaaagctgatgttgacaaaatcaggcagcagtcttgtgagactctctttcat tcttggaaagattttgaagtttgttcttctgggctgagttgcctgtcccaggtgtcagtt catttgcaaggactagagtccttgttcattattcccaggatagaagttgagcaaacagac caacaaatggcattagttgagagcctggactatttaagaggagaaatcaataaagccaca gatgactttacttcctggaagacacatctacttgcttcaggaagccaaagtggaaaccaa atgttagatgaagggtttgtggaagatttttcagaacaggtggaaactgccatccgggcc atcctttgtgccatccagaacttagcagaaagaaacagtaaaaagacagaggagaacact gaccaaagcagaccacaagaagaggacggggcagcaggcttggagggactgcaatcagga catctaacaaaactgttagaggatgatttgtgggccgacgtgagcactctgcatgtgcag aaaatcatttctgctgtctctgagctgttggagaggctgaaatcgtacggtgaagatggc acagcagcaaaacacacgttcttcagccaatcctgctgcttgttggtgcgtctggtgccc atgctctccaggtactcagacctcgtcctcttcttcctgaccatgtctttggcaactcac cgtagcactgcaaagctgctgtctgttcttgcccatgtctttacagagctcgcccaggag ggattttgcctgcccaaagaattcatggaagattcagcaggagagggagcaactgagttc catgactatgagggaggtggaattggggaaggcgagggcatgaaggatgtgagtgaccag attgaaaatgaagaacaggcagaagatacacttcagaaaggccaagaaaaggataaagag gatcccgactcaaaaccagacattaagggcgaggataatgccattgagatgtcagaagac tttgatgggaaaatgcatgatggggaacttgaaaaagaagaggatgatgggaaatcagac agtgagggcggagacctggataaacagatgggcgatctgaatggtgaggaagctgacaaa cttgatgagaggctttggggtgatgacgatgatgaggaagaagaagacagtaaaactgaa gaaacaggaccaggaatggatgaggaagattgtggacttgttgccaaagacgacaacttg gatgctgggaagtcaaacagagataaaaaccgagataaggaagaaaaggaagaagcagaa gttgctgatgatagacaaggccaagacaaaattaatgaacaaatagatgagagggaatat gatgagaatgaggtggatccttaccatggcaatcaggaagagctgccagaacctgaggcc ttggaccttccagatgacttgaacctggatagtgaagacaagaatggtagtgaggacaca gaccaggaagaaggagaagataatcctttggaaattaaagaaaagccaatggatactgaa gaagcaggtcatgaagctgaggaaataaaggaacagaccgaggctgaccacagtgaaggt cagggtcagcctgaacctgaagaaggccccagtgaagatgataagggtgagggagaagaa gagatggacacaggagctgatgaccaagataaagacactgctgaacatcctgaagaaaac tcagacgatgagcgtcagtctctggaggacaaggacaaggaagccaatgaggaaagtgca gacaatggcgttcctgttgaccaaggtctccagccccagaaggaggaagaagaagaagaa gggagcggggaaaactctgacacagaggagcaggtgccagaggccacggaaagggaagaa cacgattcctgcgggcagaccggggtggagagtgtgcagagtgcacaggctatggagctg gctggggccgcgcccgaaaaggagcagggaaaggaggagcacgggagtggagctgcagat gcaaaccaggcagaaggccaccaatccaacttcattgctcgattggcttcccagaaacag accaggaaggacacacagagtttcaagaggaaacctggacaggctgacaatgaacgctcc atgggtgatcacaatgagcgagtgcataagcgactgaggactgtggatatggagagccac actgagcaggggccagcccagccccacgcccaggtggaggacgcagatgcatttgagcac attaaacaaggcagtgacccttatgatgcacagacgtatgatgtggccagcaaggagcag caacagtctgcaaaagattccagcaggggtcaggaggaggagatggaggacactttcatg gacacagaggaggaagagctccaagcagcagacacagagcagctgaagccagaggagatc aagtcagggaccacagtgagccccggctatgatgaggtggacatggagacccacactgtt agaacagaagaagaccaagatcccaggaccgacatatcccagggggagacagaggatatg aaaccagagagaagccaagattcgaccattcacacagcccatcagttccttgtggacaca attttccagcccattttaaaagatgtcagtgagctaagacaggagctggagaggcagctg gaaacatggcatccacacgaatctggaaacccagaagaagagaaggctgcagtgcagatg tggcagagttacctggccgtaactgcgcctctttcccaacagttgtgtgaacagcttcgt ctcatattagagcctacccaggccgccaagctgaaaggagactatcgaactgggaagcgg ctgaacatgcggaaggtcattccatacattgctagtcaatttcggaaagacaagatttgg cttcgaaggaccaagcccagtaaacgccagtatcagatttgtttggccattgatgactct tctagcatggtagacaaccataccaaacagctggcatttgaatctttggctgtgattgga aatgctctaaccctcctggaagtgggtcagattgctgtgtgcagttttggagagtccgta aagctattacacccattccacgagcagttcagtgatttctcgggttcccagattctgcgg ctctgcaaattccagcaaaagaaaaccaagattgctcagtttctcgagtctgtagccagc atgtttgcagctgctcagcagccctcccagcacgccagtccagaaaacgcacagctcctc ctggtggtctctgatggacgcggccttttcctcgagggcaaagacagagtcctggcagca gtccaggctgcccggaatgctaacatctttgtcatttttgttgtattggacaatcccagt tcacgggattcgatcttggacatcaaagtgcccatatttaaaggacctggagagatgcct gaaatccgatcctacatggaagagttcccattcccattctacatcatccttcgcgatgtg aacgcgctccctgagacgctcagtgatgctcttaggcagtggtttgagttggtggcagcc tctgaccacctgtag

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