Panthera pardus (leopard): 109275517
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Entry
109275517 CDS
T06062
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04064
NF-kappa B signaling pathway
ppad04072
Phospholipase D signaling pathway
ppad04151
PI3K-Akt signaling pathway
ppad04380
Osteoclast differentiation
ppad04611
Platelet activation
ppad04613
Neutrophil extracellular trap formation
ppad04625
C-type lectin receptor signaling pathway
ppad04650
Natural killer cell mediated cytotoxicity
ppad04662
B cell receptor signaling pathway
ppad04664
Fc epsilon RI signaling pathway
ppad04666
Fc gamma R-mediated phagocytosis
ppad05152
Tuberculosis
ppad05167
Kaposi sarcoma-associated herpesvirus infection
ppad05168
Herpes simplex virus 1 infection
ppad05169
Epstein-Barr virus infection
ppad05171
Coronavirus disease - COVID-19
ppad05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
109275517 (SYK)
04072 Phospholipase D signaling pathway
109275517 (SYK)
04151 PI3K-Akt signaling pathway
109275517 (SYK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109275517 (SYK)
04613 Neutrophil extracellular trap formation
109275517 (SYK)
04625 C-type lectin receptor signaling pathway
109275517 (SYK)
04650 Natural killer cell mediated cytotoxicity
109275517 (SYK)
04662 B cell receptor signaling pathway
109275517 (SYK)
04664 Fc epsilon RI signaling pathway
109275517 (SYK)
04666 Fc gamma R-mediated phagocytosis
109275517 (SYK)
09158 Development and regeneration
04380 Osteoclast differentiation
109275517 (SYK)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
109275517 (SYK)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
109275517 (SYK)
05168 Herpes simplex virus 1 infection
109275517 (SYK)
05167 Kaposi sarcoma-associated herpesvirus infection
109275517 (SYK)
05169 Epstein-Barr virus infection
109275517 (SYK)
09171 Infectious disease: bacterial
05152 Tuberculosis
109275517 (SYK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppad01001
]
109275517 (SYK)
Enzymes [BR:
ppad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109275517 (SYK)
Protein kinases [BR:
ppad01001
]
Non-receptor tyrosine kinases
SYK family
109275517 (SYK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
109275517
NCBI-ProteinID:
XP_019319296
Ensembl:
ENSPPRG00000023709
UniProt:
A0A9V1GC05
LinkDB
All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MAGGVAADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
AHHYTIERELNGTYAIAGGRAHGSPAELCHYHSQECDGLVCLLKKPFHRPPGVQPKTGPF
EDLKESLIREYVRQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQ
IVLIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQL
VEHYSYKADGLLRVLTVPCQKIGGQTGNINFGARAPLPGPHPATWSAGGIISRIKSYSFP
KPGHRKASTSQGSRPESAVTFNPYEPDRGPWPTDRDAQREALPMDTEVYESPYADPEEIR
PKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLA
EANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVS
MGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWY
APECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPTGCPR
EMYELMKLCWTYEVENRPGFAAVELRLRNYYYDVVN
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggcgggaggcgtggcggccgacagcgccaaccacctgcccttcttctttggcaacatc
acccgggaggaggcggaggactacctggtgcaggggggcatgagcgacgggctgtacctg
ctgcgccagagccgcaattacctgggcggcttcgcgctgtccgtggcgcacgggaggaag
gcgcaccactacaccatcgagcgcgagctcaacggcacgtacgccatcgcgggcggcagg
gctcacggcagccccgccgagctgtgccactaccactcccaggagtgcgacggcctcgtc
tgcctcctcaagaagcccttccaccggccgcccggcgtgcagcccaagaccggcccgttc
gaggacctgaaggagagcctcatccgggagtacgtgaggcagacctggaacctgcagggc
caggctctggagcaggccattatcagccagaaaccacagctggagaagctgatcgccacc
acggcccacgagaaaatgccctggttccacggcaaaatctcacgggtcgaatcggagcag
attgtcctgatcggatccaagacaaatggaaaatttttgatccgggacaggaacgacaac
gggtcttacgccctgtgcctgctgcatgaggggaaggtactgcactaccgcatcgataag
gacaaaacggggaagctctccatccccgacgggaagaagttcgacacgctctggcagcta
gtggagcattattcttataaagcagatgggctgttaagagttcttacagttccgtgtcag
aaaattggcgggcagacaggaaatatcaacttcggagcccgggcgcccctcccaggtcca
catcctgcaacatggtcagcgggtggaattatctcaagaatcaaatcatactccttccca
aagcctggccacagaaaggcctccacatcccaagggagccggccagagagcgccgtgacc
ttcaatccgtacgagccggaccgcgggccctggcccacggacagagacgcccagagagag
gccttgcccatggacaccgaggtgtatgaaagcccgtatgcggaccccgaggagatcagg
cccaaggaagtctacctggaccgcaagctgctgaccctggaggacaacgaactgggctct
ggtaacttcgggaccgtgaagaagggctactaccagatgaaaaaagtcgtgaaaacggtg
gctgtgaagattctgaagaacgaggctaacgaccccgctcttaaagatgagttattagcg
gaagccaatgtcatgcagcagctcgataacccttacatcgtgcgcatgatcggcatctgt
gaagccgagtcctggatgctggtgatggagatggcggaactgggtccgctcaacaagtat
ttacagcagaacaggcacgtcaaggataagaacatcatagagctggttcatcaggtttct
atgggaatgaagtatctggaggagagcaattttgtgcacagagatctggcggcaagaaac
gtcttgctggttactcaacactatgccaagatcagtgattttggactttccaaagcgctc
cgtgctgatgaaaactactacaaggcccagacccacgggaagtggccggtcaagtggtac
gcccccgagtgcatcaactactacaagttctccagcaagagtgacgtctggagcttcggc
gtgttgatgtgggaggcgttctcctacgggcagaagccgtaccggggcatgaagggaagt
gaggtttcggccatgctggagaaaggagagagaatggggtgccccacggggtgtccaagg
gagatgtacgagctgatgaagctgtgctggacgtatgaggtggagaacaggcccggattc
gcagccgtggaactgcgtctacgcaattattactacgacgtggtcaactaa
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