Pan paniscus (bonobo): 100967981 Help Entry 100967981         CDS       T02283                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism pps  Pan paniscus (bonobo) Pathway pps01521   EGFR tyrosine kinase inhibitor resistance pps04010   MAPK signaling pathway pps04012   ErbB signaling pathway pps04014   Ras signaling pathway pps04015   Rap1 signaling pathway pps04020   Calcium signaling pathway pps04066   HIF-1 signaling pathway pps04070   Phosphatidylinositol signaling system pps04071   Sphingolipid signaling pathway pps04072   Phospholipase D signaling pathway pps04150   mTOR signaling pathway pps04151   PI3K-Akt signaling pathway pps04261   Adrenergic signaling in cardiomyocytes pps04270   Vascular smooth muscle contraction pps04310   Wnt signaling pathway pps04360   Axon guidance pps04370   VEGF signaling pathway pps04510   Focal adhesion pps04540   Gap junction pps04613   Neutrophil extracellular trap formation pps04650   Natural killer cell mediated cytotoxicity pps04664   Fc epsilon RI signaling pathway pps04666   Fc gamma R-mediated phagocytosis pps04670   Leukocyte transendothelial migration pps04713   Circadian entrainment pps04720   Long-term potentiation pps04723   Retrograde endocannabinoid signaling pps04724   Glutamatergic synapse pps04725   Cholinergic synapse pps04726   Serotonergic synapse pps04727   GABAergic synapse pps04728   Dopaminergic synapse pps04730   Long-term depression pps04750   Inflammatory mediator regulation of TRP channels pps04911   Insulin secretion pps04912   GnRH signaling pathway pps04916   Melanogenesis pps04918   Thyroid hormone synthesis pps04919   Thyroid hormone signaling pathway pps04921   Oxytocin signaling pathway pps04925   Aldosterone synthesis and secretion pps04926   Relaxin signaling pathway pps04928   Parathyroid hormone synthesis, secretion and action pps04929   GnRH secretion pps04933   AGE-RAGE signaling pathway in diabetic complications pps04935   Growth hormone synthesis, secretion and action pps04960   Aldosterone-regulated sodium reabsorption pps04961   Endocrine and other factor-regulated calcium reabsorption pps04970   Salivary secretion pps04971   Gastric acid secretion pps04972   Pancreatic secretion pps05017   Spinocerebellar ataxia pps05022   Pathways of neurodegeneration - multiple diseases pps05031   Amphetamine addiction pps05032   Morphine addiction pps05143   African trypanosomiasis pps05146   Amoebiasis pps05161   Hepatitis B pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05170   Human immunodeficiency virus 1 infection pps05171   Coronavirus disease - COVID-19 pps05200   Pathways in cancer pps05205   Proteoglycans in cancer pps05206   MicroRNAs in cancer pps05207   Chemical carcinogenesis - receptor activation pps05214   Glioma pps05223   Non-small cell lung cancer pps05225   Hepatocellular carcinoma pps05231   Choline metabolism in cancer pps05415   Diabetic cardiomyopathy pps05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100967981 (PRKCA)    04012 ErbB signaling pathway     100967981 (PRKCA)    04014 Ras signaling pathway     100967981 (PRKCA)    04015 Rap1 signaling pathway     100967981 (PRKCA)    04310 Wnt signaling pathway     100967981 (PRKCA)    04370 VEGF signaling pathway     100967981 (PRKCA)    04066 HIF-1 signaling pathway     100967981 (PRKCA)    04020 Calcium signaling pathway     100967981 (PRKCA)    04070 Phosphatidylinositol signaling system     100967981 (PRKCA)    04072 Phospholipase D signaling pathway     100967981 (PRKCA)    04071 Sphingolipid signaling pathway     100967981 (PRKCA)    04151 PI3K-Akt signaling pathway     100967981 (PRKCA)    04150 mTOR signaling pathway     100967981 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100967981 (PRKCA)    04540 Gap junction     100967981 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100967981 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     100967981 (PRKCA)    04664 Fc epsilon RI signaling pathway     100967981 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     100967981 (PRKCA)    04670 Leukocyte transendothelial migration     100967981 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     100967981 (PRKCA)    04929 GnRH secretion     100967981 (PRKCA)    04912 GnRH signaling pathway     100967981 (PRKCA)    04921 Oxytocin signaling pathway     100967981 (PRKCA)    04926 Relaxin signaling pathway     100967981 (PRKCA)    04935 Growth hormone synthesis, secretion and action     100967981 (PRKCA)    04918 Thyroid hormone synthesis     100967981 (PRKCA)    04919 Thyroid hormone signaling pathway     100967981 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     100967981 (PRKCA)    04916 Melanogenesis     100967981 (PRKCA)    04925 Aldosterone synthesis and secretion     100967981 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100967981 (PRKCA)    04270 Vascular smooth muscle contraction     100967981 (PRKCA)   09154 Digestive system    04970 Salivary secretion     100967981 (PRKCA)    04971 Gastric acid secretion     100967981 (PRKCA)    04972 Pancreatic secretion     100967981 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100967981 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     100967981 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     100967981 (PRKCA)    04727 GABAergic synapse     100967981 (PRKCA)    04725 Cholinergic synapse     100967981 (PRKCA)    04728 Dopaminergic synapse     100967981 (PRKCA)    04726 Serotonergic synapse     100967981 (PRKCA)    04720 Long-term potentiation     100967981 (PRKCA)    04730 Long-term depression     100967981 (PRKCA)    04723 Retrograde endocannabinoid signaling     100967981 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100967981 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     100967981 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     100967981 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100967981 (PRKCA)    05206 MicroRNAs in cancer     100967981 (PRKCA)    05205 Proteoglycans in cancer     100967981 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     100967981 (PRKCA)    05231 Choline metabolism in cancer     100967981 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100967981 (PRKCA)    05214 Glioma     100967981 (PRKCA)    05223 Non-small cell lung cancer     100967981 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100967981 (PRKCA)    05161 Hepatitis B     100967981 (PRKCA)    05171 Coronavirus disease - COVID-19     100967981 (PRKCA)    05164 Influenza A     100967981 (PRKCA)    05163 Human cytomegalovirus infection     100967981 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     100967981 (PRKCA)    05143 African trypanosomiasis     100967981 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100967981 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     100967981 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     100967981 (PRKCA)    05032 Morphine addiction     100967981 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100967981 (PRKCA)    05415 Diabetic cardiomyopathy     100967981 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100967981 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100967981 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pps01001]     100967981 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pps04131]     100967981 (PRKCA) Enzymes [BR:pps01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100967981 (PRKCA) Protein kinases [BR:pps01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100967981 (PRKCA) Membrane trafficking [BR:pps04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     100967981 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Kinase-like DUF4656 Motif Other DBs NCBI-GeneID:  100967981 NCBI-ProteinID:  XP_003812415 Ensembl:  ENSPPAG00000031670 LinkDB All DBs Position 17:60246485..60747158 Genome browser AA seq 672 aa AA seqDB search MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMVGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccgggcaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa tttgttactttttcttgtccgggtgcggataagggacccgacactgatgaccccaggagc aagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtca ctgctctatggacttatccatcaagggatgaaatgtgacacctgcgatatgaacgttcac aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacactgagaagaggggg cggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagatgca aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt attcctgatcccaagaatgaaagcaagcaaaaaaccaaaaccatccgctccacactaaat ccgcagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc tttggagtttcagagctgatgaagatgccagccagtggatggtacaagttgcttaaccaa gaagaaggtgagtactacaatgtacccattccggaaggggacgaagaaggaaacatggaa ctcaggcagaaattcgagaaagccaaacttggccctgctggcaacaaagtcatcagtccc tctgaagacaggaaacaaccttccaacaaccttgaccgagtgaaactcacggacttcaat ttcctcatggtgttgggaaaggggagttttggaaaggtgatgcttgccgacaggaagggc acagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgattcaggatgatgac gtggagtgcaccatggtagaaaagcgagtcttggccctgcttgacaaacccccgttcttg acgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatatgtc aacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca gtattctatgcagcagagatttccatcggattgttctttcttcataaaagaggaatcatt tacagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaattgct gactttgggatgtgcaaggaacacatgatggttggagtcacgaccaggaccttctgtggg actccagattatattgccccagagataatcgcttatcagccgtatggaaaatctgtggac tggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggt gaagatgaagacgagctatttcagtctatcatggagcacaacgtttcctatccaaaatcc ttgtccaaggaggctgtttctatctgcaaaggactgatgaccaaacacccagccaagcgg ctgggctgtgggcctgagggggagagggacgtgagagaacatgccttcttccggaggatc gactgggaaaaactggagaacagggagatccagccaccattcaagcccaaagtgtgcggc aaaggagcagagaactttgacaagttcttcacacgaggacagcccgtcttaacaccgcct gatcagctggttattgctaatatagaccagtctgattttgaagggttctcgtatgtcaac ccccagtttgtgcaccccatcttacagagtgcagtatga

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