Pseudomonas putida DOT-T1E: T1E_2648
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Entry
T1E_2648 CDS
T02181
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ppx
Pseudomonas putida DOT-T1E
Pathway
ppx00010
Glycolysis / Gluconeogenesis
ppx00020
Citrate cycle (TCA cycle)
ppx00620
Pyruvate metabolism
ppx00785
Lipoic acid metabolism
ppx01100
Metabolic pathways
ppx01110
Biosynthesis of secondary metabolites
ppx01120
Microbial metabolism in diverse environments
ppx01200
Carbon metabolism
ppx01210
2-Oxocarboxylic acid metabolism
Module
ppx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ppx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
T1E_2648 (aceE)
00020 Citrate cycle (TCA cycle)
T1E_2648 (aceE)
00620 Pyruvate metabolism
T1E_2648 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
T1E_2648 (aceE)
Enzymes [BR:
ppx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
T1E_2648 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Stevor
Motif
Other DBs
NCBI-ProteinID:
AFO48489
UniProt:
I7C9N6
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Position
2898925..2901570
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AA seq
881 aa
AA seq
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MQDLDPIETQEWLDALESVLDKEGEDRAHYLMTRMGELATRSGSQLPYAITTPYRNTIPV
THEARMPGDLFMERRIRSMVRWNALAMVMRTNLKDSDLGGHISSFASSATLYDIGFNYFF
QAPTEEHGGDLVFFQGHASPGVYARAFMEGRISEDQMNNFRQEVDGNGLSSYPHPWLMPD
FWQFPTVSMGLGPIQAIYQARFMKYLEARGFIPAGKQKVWCFMGDGECDEPESLGAIALA
GREKLDNLIFVINCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVNKVVWGRFWDPLLAKD
TNGALQRRMDEVIDGEYQNYKAKDGAYVREHFFNTPELKAMVEDLSDEEIWKLNRGGHDP
YKVYAAYHQAVNHKEQPTVILAKTIKGYGTGAGEAKNTAHNTKKVDVDSLRHFRDRFDIP
VKDADLENLPFFKPEEGSAEAKYLAERRAALGGFVPQRRAKSFSVPTPPLETLKAILDGS
GDREISTTMAFVRILAQLVKDKDIGQRIVPIIPDEARTFGMEGMFRQLGIYSSVGQLYEP
VDKDQVMFYREDKKGQILEEGINEAGAMSSFIAAGTSYSCHNQPMLPFYIFYSMFGFQRI
GDLAWAAGDSRTRGFLIGGTAGRTTLNGEGLQHEDGHSHMMAGTIPNCRTYDPTYGYELA
VIIQDGMKKMTEEQQDIFYYITVMNESYQQPAMPAGVEEGIIKGMYLLEEDTREAAHHVQ
LMGSGTILREVREAAKILREEFNVGADVWSVTSFNELRRDGLAVERANRLKPGQKPQQTY
VEQCLNGRKGPVIASTDYMKLFAEQIRQWVPSKEFKVLGTDGYGRSDSRKKLRHFFEVDR
HFVVLAALEALADRGEIEPKVVADAIVKFGIDPDKRNPLDC
NT seq
2646 nt
NT seq
+upstream
nt +downstream
nt
atgcaagacctcgatccaatcgaaacccaggaatggctggatgccctggagtcggtcctc
gacaaagaaggcgaagaccgcgctcattacctgatgacccgtatgggcgagctggccacc
cgtagtggctcccagctgccgtatgcgatcaccacgccataccgcaacaccatccctgtc
acccacgaagcacgcatgcctggcgacctgttcatggaacgccgcattcgctcgatggtg
cgttggaacgcgctggccatggtcatgcgtaccaacctgaaagactcggacctgggcgga
cacatctctagcttcgcctccagtgccaccctgtacgacatcggcttcaactacttcttc
caggcccctaccgaagaacacggcggcgacctggtcttcttccagggccacgcttcgcct
ggcgtctacgcccgtgccttcatggaaggccgtatcagcgaagaccagatgaacaacttc
cgtcaggaagtggacggcaacggcctgtcttcgtacccgcacccatggttgatgcctgac
ttctggcagttcccgaccgtttcgatgggtctgggcccaatccaggcgatctaccaggca
cgcttcatgaagtacctggaagcccgtggcttcatcccggccggcaagcagaaggtctgg
tgcttcatgggcgacggtgagtgcgacgagccggaatccctgggtgcaatcgccctggcc
ggccgcgagaagctggacaacctgatcttcgtcatcaactgcaacctgcagcgcctcgac
ggcccggttcgcggcaacggcaagatcatccaggaactcgaaggcgtgttccgtggcggt
ggctggaacgtcaacaaagtcgtctggggccgtttctgggacccactgctggccaaggac
accaacggtgccctgcagcgccgcatggacgaagtcatcgacggcgaataccagaactac
aaagccaaagacggcgcgtacgttcgcgagcacttcttcaacaccccggaactcaaggcc
atggtcgaagacctgtccgacgaagagatctggaagctcaaccgtggcggtcacgacccg
tacaaggtctacgcggcgtatcaccaggctgtgaaccacaaagagcagccgaccgtcatc
ctggccaagaccatcaagggttacggcaccggtgctggcgaagccaagaacaccgcgcac
aacaccaagaaggtcgacgtcgacagcctgcgtcacttccgtgaccgcttcgacatcccg
gtcaaggatgccgacctggagaacctgccgttcttcaagccggaagaaggttctgccgaa
gccaagtacctggccgagcgccgcgcagccctgggtggcttcgtaccgcagcgccgtgcc
aagagcttcagcgtgccgaccccgccactggaaacgctgaaagcgatcctggacggctcg
ggcgaccgcgaaatctccaccaccatggccttcgtgcgtattctggcgcagctggtcaag
gacaaggacatcggccagcgcatcgtcccgatcatcccggacgaagcccgtaccttcggt
atggaaggcatgttccgccagttgggcatctactcgtcggtcggccagctctacgagcca
gtcgataaagaccaggtgatgttctaccgcgaagacaagaagggccagatcctcgaggaa
ggcatcaacgaagccggcgccatgtcgtcgttcatcgctgccggtacctcgtacagctgc
cacaaccagccgatgctgccgttctacatcttctactcgatgttcggtttccagcgtatt
ggcgacctggcctgggccgctggcgacagccgcacccgtggcttcctgatcggcggtacc
gccggccgtaccaccctcaacggtgaaggcctgcagcacgaagacggtcacagccacatg
atggcgggcaccatcccgaactgccgcacctacgatccgacctacggctacgagctggcg
gtgatcatccaggacggcatgaagaagatgaccgaagagcaacaggacatcttctactac
atcaccgtgatgaacgaatcctaccagcagccagccatgccggccggtgtcgaggaaggc
atcatcaagggcatgtacctgctggaagaggacacccgcgaagccgcacaccacgtacag
ctgatgggctccggcaccatcctgcgcgaagtccgcgaagccgcgaagatcctgcgtgaa
gagttcaacgtcggtgccgacgtgtggagcgtcaccagcttcaacgaactgcgccgtgac
ggcctggccgtggaacgcgccaaccgcctgaagcctggccagaagccacagcagacctac
gtcgagcagtgcctgaacggtcgcaaaggcccggttatcgcctctaccgactacatgaag
ctgttcgccgagcagattcgccagtgggtaccgagcaaagagttcaaagtcctgggtacc
gacggttacggtcgcagcgacagccgcaagaagctgcgtcacttcttcgaagtcgaccgc
cacttcgtggtgctggctgccctggaagccctggctgaccgtggcgagatcgaacccaag
gttgttgcagacgctatcgtcaagttcggtatcgacccggacaagcgcaacccactggac
tgctga
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