Polymorphospora rubra: Prubr_31940
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Entry
Prubr_31940 CDS
T07190
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pry
Polymorphospora rubra
Pathway
pry00860
Porphyrin metabolism
pry01100
Metabolic pathways
pry01110
Biosynthesis of secondary metabolites
pry01120
Microbial metabolism in diverse environments
pry01240
Biosynthesis of cofactors
Module
pry_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
pry00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Prubr_31940 (hemD)
Enzymes [BR:
pry01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Prubr_31940 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Prubr_31940 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BCJ66173
UniProt:
A0A810N381
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Position
3396651..3398231
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AA seq
526 aa
AA seq
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MTRTRKPAGRIAFVGAGPGDPGLLTRRAHDALVDSDQVIYDRGVPESLLDAIRAEAKEDA
QFTPAEGAPGDVAKVLISAARSGLSAVHLVAGDPFGHDSVVKEVQAVARTAVHFEVVPGV
GQAEGVAAYAGVPLPGVRTAADVDDVGALDFEALAAAVNRGSLALAVDAGDLAAVRDGLL
AVGVDGTTPVGVTGDGTGETQYTTSSSVDSFVAAALGFTGRVVLTLGAGVTQRDKLSWWE
NRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATADAVRAFGIQPELVPSGEQ
SSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PAHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgcaggccgcatcgcgttcgtcggggccggccccggcgac
cccggcctgctgacccgccgggcgcacgacgccctggtcgactccgaccaggtgatctac
gaccggggcgtgccggagtcgctgctcgacgcgatccgcgccgaagccaaggaagatgcg
cagttcacgcctgccgagggagcgcccggcgacgtcgccaaggtgctgatctcggcggcc
cggtccggcctgtccgccgtacacctcgtcgccggtgaccccttcggtcacgactccgtg
gtcaaggaggtgcaggcggtcgcccgtaccgcggtccacttcgaggtggtgcccggtgtc
gggcaggccgagggcgtcgccgcctacgccggggtgccgctgcccggcgtacgcaccgcg
gccgacgtcgacgacgtcggtgcgctggacttcgaggcgctcgcggcggcggtcaaccgt
ggctccctcgccctcgccgtcgacgccggtgacctcgccgccgtccgcgacgggctgctc
gccgtcggcgtcgacggcaccaccccggtcggggtgaccggtgacggcaccggtgagacg
cagtacacgaccagttcgagcgtcgacagcttcgtcgccgccgcgctcggcttcaccggt
cgcgtcgtgctcaccctgggcgccggtgtcacccagcgcgacaagctgagctggtgggag
aaccgcccgctgtacggttggaaggtgctcgtcccgcgcaccaaggagcaggccggtgcg
atgagcgcccgactgcgggcgtacggggcgatcccgtgcgaggtgccgacgatcgcggtc
gagccgccgcgtaccccggcccagatggagcgcgccgtcaagggcctggtcgacggccgg
tacgcctgggtcatcttcacctcggtcaacgcggtccgcgcggtctgggagaagttcgcc
gagcacgggctcgacgcccggcacttcggcggtgtcaagatcgcgtgcatcggtgaggcg
accgccgacgccgtccgcgccttcggcatccagcccgagctggtcccctccggtgagcag
tcctcggagggcctgctcgccgagttctcgccgcacgacgagatcctcgacccggtcggc
cgggtgctgctgccgcgtgccgacatcgccaccgagacgctggccgccggcctcaccgaa
cgcggctgggaggtcgacgacgtcaccgcctaccgcaccgtccgggccgcgccgccgccg
gccgagatccgcgacgcgatcaagtccggcggcttcgacgcggtgctcttcacgtcgtcg
tcgaccgtacgcaacctggtcggcatcgccggcaagccgcacgcccgcaccgtcgtggcc
gtgatcggcccgaagaccgcggagaccgcgaccgagttcggacttcgggtcgacgtgcag
cccgcacacgcctccgtgccggacctggtcgaggcgctcgcggcgtacgctgtggagttg
cgcgagaagctggccgccatgccggccaagcagcgtcgcggctcgaaggtgcaggggccg
acggcgctgcggttccgctga
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