Pseudonocardia sp. HH130629-09: XF36_00490
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Entry
XF36_00490 CDS
T04082
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pseh
Pseudonocardia sp. HH130629-09
Pathway
pseh00860
Porphyrin metabolism
pseh01100
Metabolic pathways
pseh01110
Biosynthesis of secondary metabolites
pseh01120
Microbial metabolism in diverse environments
pseh01240
Biosynthesis of cofactors
Module
pseh_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
pseh_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pseh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
XF36_00490
Enzymes [BR:
pseh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
XF36_00490
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
XF36_00490
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ALE81782
UniProt:
A0A0M5LV84
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Position
110401..111942
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AA seq
513 aa
AA seq
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MTGPANTSGRIAFVGSGPGDPALLTVRARDVLTGSPLVITDPDVPEGILALAADGAEVRP
AVGQPADIASDLLSEAGQGRSVARLVSGDPLTNDAVVAEAMAVSASGTPFDVVPGVPSST
AVPAYAGVALGSAHVEADVRAGVDWAALAASPGPVVLHATSALLGDVAAGLTAQGVPDET
PVAITAGGTTSTQRTISSSVGRIAADGGDLEGALVLTVGEAAGRRGELSWWESRALYGWR
VLVPRTKDQAGVMSERLRMHGAIPEEVPTIAVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVKAVWEKFGEFGLDARAFSGVKIACVGRSTAEKVREFGIEPELVPDIDEAQSSTSEG
LLDIFPPHDDVLDPVDRVLLPRADIATETLSAGLQERGWEVDDVTAYRTVRAAPPPAPIR
EAIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPATAETAREFGLRVDVQPEES
RVPTLVDALASHTAKLRAEGNLPPPKKVKARRR
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgacaggacctgccaacacctcggggcggatcgccttcgtgggcagcggaccgggggac
ccggcgctgctcaccgtgcgtgcccgggacgtgctcaccggctcgccgctggtcatcacc
gacccggacgtgcccgagggcatcctcgccctggccgcggacggcgccgaggtgcgcccg
gccgtcgggcagcccgccgacatcgcgagcgacctgctcagcgaggccggtcagggccgc
tcggtggcccggctggtctccggtgacccgctgaccaacgacgccgtcgtcgccgaggcg
atggccgtgtccgcctcgggcacgccgttcgacgtggttccgggcgtcccgtcctcgacc
gcggtcccggcctacgccggtgtcgcgctcgggtcggcgcacgtcgaggccgacgtccgc
gcgggtgtcgactgggccgcgctggccgcgagcccgggcccggtcgtgctgcacgcgacg
agcgcgctgctcggcgacgtcgccgccggtctgaccgcccagggcgtcccggacgagacg
ccggtcgcgatcaccgcgggcggcaccacctccacccagcggaccatctcgtcgtcggtc
gggcggatcgccgccgacggcggtgacctggagggcgcgctcgtcctcaccgtcggcgag
gccgccggtcgccgtggcgagctgtcctggtgggagtcgcgcgcgctctacggctggcgg
gtcctggtgccgcgcaccaaggaccaggccggcgtgatgagcgagcggctgcggatgcac
ggcgccatcccggaggaggtgccgacgatcgccgtcgagccgccccggtcgcccgcgcag
atggagcgctcggtcaagggcctggtcgacggccgctaccagtgggtcgtgttcacctcg
accaacgcggtcaaggccgtctgggagaagttcggtgagttcggcctcgacgcccgcgcc
ttctccggcgtgaagatcgcctgcgtcggccgctcgaccgcggagaaggtccgcgagttc
ggcatcgagcccgagctcgtccccgacatcgacgaggctcagtcctcgacgtccgagggc
ctgctggacatcttcccgccgcacgacgacgtcctcgacccggtcgaccgggtgctgctc
ccgcgcgccgacatcgccaccgagacgctgtcggccgggctgcaggagcgcggctgggag
gtcgacgacgtgacggcctaccggaccgtccgggccgccccgccgcccgcgccgatccgt
gaggcgatcaagaccggcggcttcgacgcggtgtgcttcacctcgtcgtcgacggtgcgg
aacctggtcggcatcgccggcaagccgcacgcccggaccctggtcgcctgcatcggcccg
gccaccgcggagaccgcgcgcgagttcggcctgcgggtcgacgtgcagcccgaggagtcc
cgggtcccgaccctggtcgacgcgctggccagccacaccgcgaagctgcgcgccgagggc
aacctgccgccgccgaagaaggtgaaggctcgccgccgctga
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