Phocoena sinus (vaquita): 116742406 Help Entry 116742406         CDS       T07759                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism psiu  Phocoena sinus (vaquita) Pathway psiu00230   Purine metabolism psiu01100   Metabolic pathways psiu01522   Endocrine resistance psiu04015   Rap1 signaling pathway psiu04020   Calcium signaling pathway psiu04022   cGMP-PKG signaling pathway psiu04024   cAMP signaling pathway psiu04062   Chemokine signaling pathway psiu04072   Phospholipase D signaling pathway psiu04114   Oocyte meiosis psiu04211   Longevity regulating pathway psiu04213   Longevity regulating pathway - multiple species psiu04261   Adrenergic signaling in cardiomyocytes psiu04270   Vascular smooth muscle contraction psiu04371   Apelin signaling pathway psiu04540   Gap junction psiu04611   Platelet activation psiu04713   Circadian entrainment psiu04714   Thermogenesis psiu04720   Long-term potentiation psiu04723   Retrograde endocannabinoid signaling psiu04724   Glutamatergic synapse psiu04725   Cholinergic synapse psiu04727   GABAergic synapse psiu04742   Taste transduction psiu04750   Inflammatory mediator regulation of TRP channels psiu04911   Insulin secretion psiu04912   GnRH signaling pathway psiu04913   Ovarian steroidogenesis psiu04914   Progesterone-mediated oocyte maturation psiu04915   Estrogen signaling pathway psiu04916   Melanogenesis psiu04918   Thyroid hormone synthesis psiu04921   Oxytocin signaling pathway psiu04923   Regulation of lipolysis in adipocytes psiu04925   Aldosterone synthesis and secretion psiu04926   Relaxin signaling pathway psiu04927   Cortisol synthesis and secretion psiu04928   Parathyroid hormone synthesis, secretion and action psiu04934   Cushing syndrome psiu04935   Growth hormone synthesis, secretion and action psiu04970   Salivary secretion psiu04971   Gastric acid secretion psiu04972   Pancreatic secretion psiu04976   Bile secretion psiu05032   Morphine addiction psiu05163   Human cytomegalovirus infection psiu05166   Human T-cell leukemia virus 1 infection psiu05200   Pathways in cancer psiu05207   Chemical carcinogenesis - receptor activation psiu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:psiu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     116742406 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     116742406 (ADCY8)    04371 Apelin signaling pathway     116742406 (ADCY8)    04020 Calcium signaling pathway     116742406 (ADCY8)    04072 Phospholipase D signaling pathway     116742406 (ADCY8)    04024 cAMP signaling pathway     116742406 (ADCY8)    04022 cGMP-PKG signaling pathway     116742406 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     116742406 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     116742406 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     116742406 (ADCY8)    04062 Chemokine signaling pathway     116742406 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     116742406 (ADCY8)    04923 Regulation of lipolysis in adipocytes     116742406 (ADCY8)    04912 GnRH signaling pathway     116742406 (ADCY8)    04913 Ovarian steroidogenesis     116742406 (ADCY8)    04915 Estrogen signaling pathway     116742406 (ADCY8)    04914 Progesterone-mediated oocyte maturation     116742406 (ADCY8)    04921 Oxytocin signaling pathway     116742406 (ADCY8)    04926 Relaxin signaling pathway     116742406 (ADCY8)    04935 Growth hormone synthesis, secretion and action     116742406 (ADCY8)    04918 Thyroid hormone synthesis     116742406 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     116742406 (ADCY8)    04916 Melanogenesis     116742406 (ADCY8)    04925 Aldosterone synthesis and secretion     116742406 (ADCY8)    04927 Cortisol synthesis and secretion     116742406 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     116742406 (ADCY8)    04270 Vascular smooth muscle contraction     116742406 (ADCY8)   09154 Digestive system    04970 Salivary secretion     116742406 (ADCY8)    04971 Gastric acid secretion     116742406 (ADCY8)    04972 Pancreatic secretion     116742406 (ADCY8)    04976 Bile secretion     116742406 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     116742406 (ADCY8)    04727 GABAergic synapse     116742406 (ADCY8)    04725 Cholinergic synapse     116742406 (ADCY8)    04720 Long-term potentiation     116742406 (ADCY8)    04723 Retrograde endocannabinoid signaling     116742406 (ADCY8)   09157 Sensory system    04742 Taste transduction     116742406 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     116742406 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     116742406 (ADCY8)    04213 Longevity regulating pathway - multiple species     116742406 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     116742406 (ADCY8)    04714 Thermogenesis     116742406 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     116742406 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     116742406 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     116742406 (ADCY8)    05163 Human cytomegalovirus infection     116742406 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     116742406 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     116742406 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     116742406 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     116742406 (ADCY8) Enzymes [BR:psiu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      116742406 (ADCY8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  116742406 NCBI-ProteinID:  XP_032465923 Ensembl:  ENSPSNG00000015324 LinkDB All DBs Position 17:complement(69430072..69650781) Genome browser AA seq 1243 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFVHGHRGSGGG SRSSSKASDPVGGGPNHHASQLAGDSALPLYALGPGERAHSPGCTKVFPERSGSGGAGDL GFLHLDCAPSNSDFFLKGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNV LDVLTKLTLLVLHLSLASAPMDPLKGMLLGFFTGIEVVICALVVVRKDTTSHTYLQYSGV VTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVVLQ GVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETEN QRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLS TTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGL SMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPG RIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKESVS SSDSRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEI NKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFIT AIQSLFPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNV IIFASILINFLGAIVNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTC AVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLLMAM FLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKD RDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRF QDIEKIKTIGSTYMAVSGLSPEKQQCEDKWEHLCALADFSLALTESIQEINKHSFNNFEL RIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAF DYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQR QKQLLNENNTGIIKGHYNRRTLLTPSGPEPGAQAEGTDKSELP NT seq 3732 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgccttagcggcagcgaggagctctacaccattcacccg acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcaaacg gcggtgcggcacatcaccgagcagcgcttcgttcacgggcaccggggcagcggcggcggg agcagaagctccagcaaagcctcggaccctgtaggcggcggccccaaccaccacgcgtcg cagctggccggcgactcggcgcttcccctctacgcgctgggccccggggagagagcgcac agccccggctgcaccaaagtcttcccggaacgcagcggcagcgggggcgcgggcgacctg ggcttcctgcacctcgactgcgccccgagcaactcggacttcttcctcaaggggggttat agctaccgaggggtcattttccccaccctgcgcaactccttcaagtcccgggatctggag cgcctgtaccagcgctatttcctgggccagaggcgcaaatcggaggtggtgatgaacgtg ctggacgtgctgaccaaactcaccctcttggttctccacttgagcctggcctcggccccc atggacccgctcaagggcatgctgctgggcttcttcacgggcatagaggtggtgatctgc gccttggtggtggtcaggaaggacaccacctcgcacacctacctgcagtacagcggcgtg gtcacctgggtggccatgaccacccagatcttagcagcaggtctgggctatgggctcctg ggagacggcattggctacgtgctcttcacactcttcgccacctacagcatgctgccgctg ccgctcacctgggccatcctggctggcctgggcacgtcgttactgcaggtggtcctccaa ggggtcatccccaggctggcggtcatttccatcaaccaggttgtggcccaggcagtgtta ttcatgtgtatgaacacggctggaatctttatcagttacctgtcagaccgggcccagcgc caagccttcctggagacacggaggtgtgtggaagccaggctgcgcctagagacggaaaac caaagacaggagcggcttgtgctgtctgtgctccctcggtttgtcgtcctggagatgatc aatgacatgaccaacgtggaagacgagcacctgcagcatcaattccaccggatctacatc caccgctacgagaacgtcagtattctttttgcagatgtcaaaggatttaccaacctctcc acgaccttgtctgcccaggagctggtcaggatgctcaacgagctctttgctagatttgat cgactggcccatgagcatcactgccttcgcattaaaatcctgggagactgctactactgt gtttcaggacttcctgagccccgccaggaccacgcccactgctgcgttgaaatgggcctc agcatgatcaaaaccatcaggtatgtgcggtcaaggacgaagcatgacgttgacatgcgg attggaatccactcgggctcagtgctatgtggcgtgttgggtctacgaaagtggcagttt gatgtctggtcttgggatgtggatattgcaaacaaacttgaatccggaggaatccctggg aggattcacatttccaaagccacgctggactgcctcaacggtgactataatgtggaagag ggtcatggtaaagagaggaacgaattcttgaggaagcataatatagagacctatttaatt aagcagcctgaggagagtctgctgtctttgcctgaagacatcgtcaaggaatccgtgagc tcctcagacagcagaaacagtggggcgacattcacagaaggatcctggagccccgaactg ccctttgataacatagtggggaaacagaacactctggctgccctaacaagaaattcaata aatctacttccaaaccatcttgcacaagctttgcatgtccagtctgggcctgaggaaatt aacaagagaatagaacataccatcgacttgcggagtggcgataaattgagaagagagcat atcaagccattctcactgatgtttaaagactccagcctggagcacaagtattctcaaatg agagacgaagtattcaaatcaaacttggtctgtgcgtttatcgttcttctatttatcacg gcaatacaaagtttgtttccttcttcaagggtgatgccaatggccatccagttttccatc ctgattatgctgcactcggctttggtcctcatcaccacagcggaggattataagtgtttg cccctggtcctccggaaaacttgctgttggattaacgagacctatttggccaggaatgtc atcatctttgcgtccatcttgattaatttcctgggcgccatcgtaaatatcctgtggtgt gattttgacaagtcgatacccttgaagaacctgactttcaattcctcagctgtgtttaca gatatctgctcctacccagagtacttcgtcttcacgggggtgttggccatggtgacctgt gcagttttcctccgacttaactctgtcctgaagctggctgttctgttgattatgattgcc atctatgccctgctgaccgagaccatctatgcaggactctttctgcgctatgacaacctg aaccacagtggagaagatttcctggggaccaaggaggcgtcactgctgctgatggccatg ttcctcctcgctgtcttctaccatggacagcagctggagtacacggcacgcctggacttc ctctggcgagttcaggccaaagaggagatcaacgagatgaaggagctgagggaacacaac gagaacatgctccggaacatcctgcccagtcacgtggcccgccacttcctggagaaggac cgcgacaatgaggagctgtattctcaatcctatgatgctgttggggtgatgtttgcctcc atcccagggtttgcagacttctactctcagactgaaatgaacaaccaaggagtggaatgc ctacgcctgctgaatgagatcattgcggacttcgatgagctgcttggtgaagaccggttt caagacattgaaaagattaagaccattggcagcacctacatggccgtgtcaggcctgtca cctgaaaaacagcaatgtgaagataagtgggaacatctgtgtgccctggccgacttctct ctcgccctgaccgaaagcatacaggagatcaacaagcattctttcaacaattttgagctc cggattggcatcagtcacggctcagtggtagctggcgttatcggcgctaagaaaccacag tatgacatttggggcaaaaccgtgaacctggcaagtcgaatggacagcacaggagtcagc ggcagaatccaggtcccagaggagacctatctcatcctgaaggaccagggctttgccttt gactaccgaggggagatctatgtgaagggcatcagtgaacaggaaggaaaaatcaaaacg tactttctcctgggaagagtccaacccaacccattcatcctgccgccgagaagactgccc gggcagtactccttggccgcggtcgtcctgggcctcgtccagtccctcaacaggcaaagg cagaagcagctcctgaatgagaacaacacgggcatcatcaagggccattacaaccggcgg actttgctgacacccagtgggcctgagccgggagcccaagccgaaggcaccgacaagtcc gagttgccataa

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