Phocoena sinus (vaquita): 116743673
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Entry
116743673 CDS
T07759
Symbol
AKT2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu01521
EGFR tyrosine kinase inhibitor resistance
psiu01522
Endocrine resistance
psiu01524
Platinum drug resistance
psiu04010
MAPK signaling pathway
psiu04012
ErbB signaling pathway
psiu04014
Ras signaling pathway
psiu04015
Rap1 signaling pathway
psiu04022
cGMP-PKG signaling pathway
psiu04024
cAMP signaling pathway
psiu04062
Chemokine signaling pathway
psiu04066
HIF-1 signaling pathway
psiu04068
FoxO signaling pathway
psiu04071
Sphingolipid signaling pathway
psiu04072
Phospholipase D signaling pathway
psiu04140
Autophagy - animal
psiu04150
mTOR signaling pathway
psiu04151
PI3K-Akt signaling pathway
psiu04152
AMPK signaling pathway
psiu04210
Apoptosis
psiu04211
Longevity regulating pathway
psiu04213
Longevity regulating pathway - multiple species
psiu04218
Cellular senescence
psiu04261
Adrenergic signaling in cardiomyocytes
psiu04370
VEGF signaling pathway
psiu04371
Apelin signaling pathway
psiu04380
Osteoclast differentiation
psiu04510
Focal adhesion
psiu04550
Signaling pathways regulating pluripotency of stem cells
psiu04611
Platelet activation
psiu04613
Neutrophil extracellular trap formation
psiu04620
Toll-like receptor signaling pathway
psiu04625
C-type lectin receptor signaling pathway
psiu04630
JAK-STAT signaling pathway
psiu04660
T cell receptor signaling pathway
psiu04662
B cell receptor signaling pathway
psiu04664
Fc epsilon RI signaling pathway
psiu04666
Fc gamma R-mediated phagocytosis
psiu04668
TNF signaling pathway
psiu04722
Neurotrophin signaling pathway
psiu04725
Cholinergic synapse
psiu04728
Dopaminergic synapse
psiu04810
Regulation of actin cytoskeleton
psiu04910
Insulin signaling pathway
psiu04914
Progesterone-mediated oocyte maturation
psiu04915
Estrogen signaling pathway
psiu04917
Prolactin signaling pathway
psiu04919
Thyroid hormone signaling pathway
psiu04920
Adipocytokine signaling pathway
psiu04922
Glucagon signaling pathway
psiu04923
Regulation of lipolysis in adipocytes
psiu04926
Relaxin signaling pathway
psiu04929
GnRH secretion
psiu04931
Insulin resistance
psiu04932
Non-alcoholic fatty liver disease
psiu04933
AGE-RAGE signaling pathway in diabetic complications
psiu04935
Growth hormone synthesis, secretion and action
psiu04936
Alcoholic liver disease
psiu04973
Carbohydrate digestion and absorption
psiu05010
Alzheimer disease
psiu05017
Spinocerebellar ataxia
psiu05132
Salmonella infection
psiu05135
Yersinia infection
psiu05142
Chagas disease
psiu05145
Toxoplasmosis
psiu05152
Tuberculosis
psiu05160
Hepatitis C
psiu05161
Hepatitis B
psiu05162
Measles
psiu05163
Human cytomegalovirus infection
psiu05164
Influenza A
psiu05165
Human papillomavirus infection
psiu05166
Human T-cell leukemia virus 1 infection
psiu05167
Kaposi sarcoma-associated herpesvirus infection
psiu05168
Herpes simplex virus 1 infection
psiu05169
Epstein-Barr virus infection
psiu05170
Human immunodeficiency virus 1 infection
psiu05200
Pathways in cancer
psiu05205
Proteoglycans in cancer
psiu05207
Chemical carcinogenesis - receptor activation
psiu05208
Chemical carcinogenesis - reactive oxygen species
psiu05210
Colorectal cancer
psiu05211
Renal cell carcinoma
psiu05212
Pancreatic cancer
psiu05213
Endometrial cancer
psiu05214
Glioma
psiu05215
Prostate cancer
psiu05218
Melanoma
psiu05220
Chronic myeloid leukemia
psiu05221
Acute myeloid leukemia
psiu05222
Small cell lung cancer
psiu05223
Non-small cell lung cancer
psiu05224
Breast cancer
psiu05225
Hepatocellular carcinoma
psiu05226
Gastric cancer
psiu05230
Central carbon metabolism in cancer
psiu05231
Choline metabolism in cancer
psiu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
psiu05415
Diabetic cardiomyopathy
psiu05417
Lipid and atherosclerosis
psiu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116743673 (AKT2)
04012 ErbB signaling pathway
116743673 (AKT2)
04014 Ras signaling pathway
116743673 (AKT2)
04015 Rap1 signaling pathway
116743673 (AKT2)
04370 VEGF signaling pathway
116743673 (AKT2)
04371 Apelin signaling pathway
116743673 (AKT2)
04630 JAK-STAT signaling pathway
116743673 (AKT2)
04668 TNF signaling pathway
116743673 (AKT2)
04066 HIF-1 signaling pathway
116743673 (AKT2)
04068 FoxO signaling pathway
116743673 (AKT2)
04072 Phospholipase D signaling pathway
116743673 (AKT2)
04071 Sphingolipid signaling pathway
116743673 (AKT2)
04024 cAMP signaling pathway
116743673 (AKT2)
04022 cGMP-PKG signaling pathway
116743673 (AKT2)
04151 PI3K-Akt signaling pathway
116743673 (AKT2)
04152 AMPK signaling pathway
116743673 (AKT2)
04150 mTOR signaling pathway
116743673 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
116743673 (AKT2)
09143 Cell growth and death
04210 Apoptosis
116743673 (AKT2)
04218 Cellular senescence
116743673 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116743673 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
116743673 (AKT2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
116743673 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
116743673 (AKT2)
04613 Neutrophil extracellular trap formation
116743673 (AKT2)
04620 Toll-like receptor signaling pathway
116743673 (AKT2)
04625 C-type lectin receptor signaling pathway
116743673 (AKT2)
04660 T cell receptor signaling pathway
116743673 (AKT2)
04662 B cell receptor signaling pathway
116743673 (AKT2)
04664 Fc epsilon RI signaling pathway
116743673 (AKT2)
04666 Fc gamma R-mediated phagocytosis
116743673 (AKT2)
04062 Chemokine signaling pathway
116743673 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
116743673 (AKT2)
04922 Glucagon signaling pathway
116743673 (AKT2)
04923 Regulation of lipolysis in adipocytes
116743673 (AKT2)
04920 Adipocytokine signaling pathway
116743673 (AKT2)
04929 GnRH secretion
116743673 (AKT2)
04915 Estrogen signaling pathway
116743673 (AKT2)
04914 Progesterone-mediated oocyte maturation
116743673 (AKT2)
04917 Prolactin signaling pathway
116743673 (AKT2)
04926 Relaxin signaling pathway
116743673 (AKT2)
04935 Growth hormone synthesis, secretion and action
116743673 (AKT2)
04919 Thyroid hormone signaling pathway
116743673 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
116743673 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
116743673 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
116743673 (AKT2)
04728 Dopaminergic synapse
116743673 (AKT2)
04722 Neurotrophin signaling pathway
116743673 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
116743673 (AKT2)
09149 Aging
04211 Longevity regulating pathway
116743673 (AKT2)
04213 Longevity regulating pathway - multiple species
116743673 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116743673 (AKT2)
05205 Proteoglycans in cancer
116743673 (AKT2)
05207 Chemical carcinogenesis - receptor activation
116743673 (AKT2)
05208 Chemical carcinogenesis - reactive oxygen species
116743673 (AKT2)
05230 Central carbon metabolism in cancer
116743673 (AKT2)
05231 Choline metabolism in cancer
116743673 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116743673 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
116743673 (AKT2)
05212 Pancreatic cancer
116743673 (AKT2)
05225 Hepatocellular carcinoma
116743673 (AKT2)
05226 Gastric cancer
116743673 (AKT2)
05214 Glioma
116743673 (AKT2)
05221 Acute myeloid leukemia
116743673 (AKT2)
05220 Chronic myeloid leukemia
116743673 (AKT2)
05218 Melanoma
116743673 (AKT2)
05211 Renal cell carcinoma
116743673 (AKT2)
05215 Prostate cancer
116743673 (AKT2)
05213 Endometrial cancer
116743673 (AKT2)
05224 Breast cancer
116743673 (AKT2)
05222 Small cell lung cancer
116743673 (AKT2)
05223 Non-small cell lung cancer
116743673 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116743673 (AKT2)
05170 Human immunodeficiency virus 1 infection
116743673 (AKT2)
05161 Hepatitis B
116743673 (AKT2)
05160 Hepatitis C
116743673 (AKT2)
05164 Influenza A
116743673 (AKT2)
05162 Measles
116743673 (AKT2)
05168 Herpes simplex virus 1 infection
116743673 (AKT2)
05163 Human cytomegalovirus infection
116743673 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
116743673 (AKT2)
05169 Epstein-Barr virus infection
116743673 (AKT2)
05165 Human papillomavirus infection
116743673 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
116743673 (AKT2)
05135 Yersinia infection
116743673 (AKT2)
05152 Tuberculosis
116743673 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116743673 (AKT2)
05142 Chagas disease
116743673 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
116743673 (AKT2)
05017 Spinocerebellar ataxia
116743673 (AKT2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116743673 (AKT2)
05418 Fluid shear stress and atherosclerosis
116743673 (AKT2)
05415 Diabetic cardiomyopathy
116743673 (AKT2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
116743673 (AKT2)
04932 Non-alcoholic fatty liver disease
116743673 (AKT2)
04931 Insulin resistance
116743673 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
116743673 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116743673 (AKT2)
01524 Platinum drug resistance
116743673 (AKT2)
01522 Endocrine resistance
116743673 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
psiu01001
]
116743673 (AKT2)
Enzymes [BR:
psiu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
116743673 (AKT2)
Protein kinases [BR:
psiu01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
116743673 (AKT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
PH_11
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
116743673
NCBI-ProteinID:
XP_032468329
Ensembl:
ENSPSNG00000020140
LinkDB
All DBs
Position
19:12142814..12195155
Genome browser
AA seq
481 aa
AA seq
DB search
MNEVSVVKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMQAIQMVANSLKQRGPGADPM
DYKCGSPSDSCAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKASGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
VSDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDATEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaacgaggtgtctgtcgtcaaagaaggctggctccacaagcgcggtgaatacatcaag
acctggcggccccggtacttcctgctgaagagcgacggctccttcattggatataaggag
cggcccgaggcccccgaccagaccctgccccccttaaacaacttctctgttgcagaatgc
cagctgatgaagaccgagagaccgcggcccaacaccttcgtcatacgctgcctgcagtgg
accacagtcatcgagaggaccttccatgtagactctccggatgagagggaggagtggatg
caggccatccaaatggttgccaacagcctcaagcagcggggcccaggtgcggatcccatg
gactacaagtgtggctcccccagcgactcttgtgcagccgaggagatggaagtggcagtt
agcaaggcgcgggccaaggtgaccatgaatgacttcgactatctcaagctcctgggcaag
ggcacctttggcaaagtcatcctggtgcgggagaaggccagtggccgctactacgccatg
aagatcttgcggaaggaggttatcatcgctaaggatgaagtcgcccacacggtcaccgag
agccgcgtcctccagaacaccaggcacccgttcctcactgcgctgaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggagtacgccaacggtggcgagctgttcttccac
ctgtcccgggaacgcgtcttcacggaggagcgggcccgcttttatggtgcggagatcgtc
tcagccctggagtacctgcactcgcgggacgtggtgtaccgtgacatcaagctggaaaac
cttatgctggacaaagatggccacatcaagatcactgacttcggcctgtgcaaagagggc
gtcagtgatggggccaccatgaaaaccttctgtgggacccctgaatacctggcgcccgag
gtgctggaggacaacgactacggccgggcagtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgtggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcattctcatggaggagatccgcttcccgcgcacgctcagccctgaggccaagtccctg
cttgctgggctgcttaagaaggaccccaagcagaggctcggcggggggcccagtgatgcc
acggaggtcatggagcacaggttcttcctcagtatcaactggcaggacgtggtgcagaag
aagctcctgccacccttcaaacctcaggtcacatctgaggttgacacaaggtactttgac
gacgagttcaccgcccagtccatcacaatcacacccccggaccgctatgacagcctgggc
ttactcgaactggaccagcggacccacttcccccagttctcctattcggccagcatccga
gagtga
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integrated database retrieval system