Phocoena sinus (vaquita): 116746651
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Entry
116746651 CDS
T07759
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu00230
Purine metabolism
psiu01100
Metabolic pathways
psiu04927
Cortisol synthesis and secretion
psiu04934
Cushing syndrome
psiu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
116746651 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
116746651 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
116746651 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
116746651 (PDE8A)
Enzymes [BR:
psiu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
116746651 (PDE8A)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PDE8
PAS_4
PAS_3
Response_reg
PAS_8
DUF5894
Band_7_C
Motif
Other DBs
NCBI-GeneID:
116746651
NCBI-ProteinID:
XP_032474073
Ensembl:
ENSPSNG00000000747
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Position
2:complement(36407487..36596913)
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AA seq
842 aa
AA seq
DB search
MGCAQSIHASESRVVYHGGNEAEDAPVPAAPPLQPGGPRLPPVQTTAASARSCGSSLVES
EPSGGSGSGSSIVNTVAVADIQFGPMRFHPDQLQVLLVFPKEDKQCNGFCRACEKAGFKC
TVIKETQTALACFLDKHHDIIIIDHRNPQQLDGEVLCRSIRSSELSENTVIVGVVRRAVR
EESSVMSLIEAGFTRRYVENPSAMACYNELLQMEFGLVHPQLKLRACNSMFTALEKSQEA
IEITSEDHIVQYANPAFETTMGYESGELIGKDLAEVPVNEKKADLLETINACIRIGKEWQ
GICSAKEKNGDNVQQNVKILPVIGQGGKIRHYVSIVRACNGNNKATKIAECVQSDTHTDH
QSGKHNDRRKSSLDVRTAASRTSKVSSQRRRSSTARIHSMKIEAPITKAINIISAAQESS
PMPVTEALDRVLEILRTTELYSPQFDAKDDDPHAIDLVGGLMSDVFRRPSRNEYVLSTKN
LQQASSSVITPTSLHDIPSQITQAMENEECWDFDIFELEAATHKRPLIYLGLKIFARFGV
CEVLKCSETTLRSWLQIIEANYHASNPYHNSTHSADVLHATAYFLCKERIKQTLDPLDEV
TALIAATVHDLDHPGRTNSFLCNAGSELAILYNDTAVLERHHAALAFQLTTGDDKCNIFK
NMERSDYRSLRQSIIDMVLATEMTKHFEHVNKFVNSINKPLAALEEDGEADKNQEAIITM
LRTPDNRSLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVF
DRNTCSIPKSQISFIDYFITDMFAAWDAFVDLPELMQHLDNNFKYWKGLDEMKLRSLRPP
PE
NT seq
2529 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgcccagagcatccacgcttccgagagccgggtggtttaccacggcggcaac
gaggccgaggacgcgccggtccccgcggcgccgccgttgcagcccggcgggccgcgcctc
ccacccgtccagacgacggccgcctcggcccggtcctgcggctccagcctcgtggagtcc
gagccaagtggcggcagcggcagcggcagcagcatcgtcaacacggtagcagtagctgat
atacaatttggccccatgagatttcatccagatcagctccaggtacttttagtgtttccc
aaagaagataaacagtgtaatggattctgtagggcatgtgaaaaagcagggtttaagtgt
acagttatcaaggagactcagacggcccttgcctgtttcctggacaaacatcatgacatc
atcatcattgaccacagaaatccccaacagctggacggggaggtgctgtgcaggtctatc
agatcatcagaactctcagaaaacacagttattgttggtgtagtacgcagggcggttaga
gaagagtcatctgtaatgtccctcattgaggctggctttacaaggaggtatgtagaaaac
cccagcgccatggcctgttacaatgaactgctccagatggagtttggattggtgcaccca
cagctgaaactcagggcttgtaactcaatgttcactgcattagagaaaagtcaagaagca
attgaaattacaagtgaagaccacattgtacagtatgcaaatccagcatttgaaacaaca
atgggctatgagtcaggtgaattaatagggaaggatttagcagaagtgcctgtaaatgaa
aaaaaggctgatttgctcgagactataaatgcatgcatcaggataggcaaggaatggcaa
ggaatttgctctgccaaagagaaaaacggagataatgtacaacaaaatgtgaagatacta
cctgtcatcggacagggaggaaaaattagacactatgtgtccattgtcagagcatgcaat
ggcaacaataaggctacgaaaatagctgaatgtgttcagtctgacactcatacagatcat
cagtcaggcaaacataacgacaggaggaaaagctcactagatgtcagaactgctgcctct
cgaacaagcaaagtttccagccagagacgacgctcctccacggcccggatacattccatg
aagatcgaggcgcccatcaccaaggcaatcaatatcatcagtgctgcccaggaaagcagt
cccatgcctgtgacagaagccttagatcgtgtgctggaaattctgagaaccactgaatta
tattccccacaattcgatgctaaggacgatgatcctcatgccatcgaccttgttgggggc
ttaatgtctgacgtttttcgaagaccatccaggaatgagtatgttctttcaacaaaaaac
cttcaacaggcttccagcagtgtgatcacccccacctcccttcacgacatcccgtcacag
ataactcaggccatggaaaatgaggaatgctgggactttgatatttttgaactggaggct
gccactcataaaaggcctttgatttatcttggtctcaaaatatttgctcgctttggagtc
tgtgaagtcttaaaatgctctgagacaacgctgagatcgtggttgcaaattatcgaagcc
aattatcatgcttctaacccctaccacaattctacacattctgccgacgtgcttcacgcc
actgcctattttctctgcaaggagaggataaagcaaactttagatccacttgatgaggtc
actgccctcattgcagccactgtccatgacctggaccaccccgggagaaccaactccttc
ctgtgcaatgctgggagtgagctggccattctgtacaacgacactgctgtgctcgagaga
caccacgcggccttggccttccagctgaccactggtgatgataagtgcaacatctttaaa
aacatggagaggagtgactaccggtcgctgcgccagagtattattgacatggtcttagcc
acagagatgacaaagcactttgagcacgtcaacaaatttgtcaacagcatcaacaagccc
ttggcagcattagaggaagatggggaagctgataaaaatcaagaagccataatcactatg
ctcagaactccagacaaccgcagtttgatcaaacgaatgctgattaagtgtgctgatgtg
tccaatccctgccgacccctggagcagtgcattgagtgggccgcacgtatctcagaagaa
tatttttctcagactgatgaagagaagcgacaggacttgcctgtggtgatgccagttttt
gacagaaatacctgcagcatccccaaatcccaaatctctttcattgactacttcatcaca
gacatgtttgctgcttgggacgcctttgtagacctgcctgagctaatgcagcatcttgac
aacaattttaaatactggaagggactggacgaaatgaagctgcggagcctccgcccacct
cctgaatag
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