Phocoena sinus (vaquita): 116756336
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Entry
116756336 CDS
T07759
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu01521
EGFR tyrosine kinase inhibitor resistance
psiu04151
PI3K-Akt signaling pathway
psiu04217
Necroptosis
psiu04380
Osteoclast differentiation
psiu04550
Signaling pathways regulating pluripotency of stem cells
psiu04620
Toll-like receptor signaling pathway
psiu04621
NOD-like receptor signaling pathway
psiu04630
JAK-STAT signaling pathway
psiu04658
Th1 and Th2 cell differentiation
psiu04659
Th17 cell differentiation
psiu05140
Leishmaniasis
psiu05145
Toxoplasmosis
psiu05152
Tuberculosis
psiu05160
Hepatitis C
psiu05161
Hepatitis B
psiu05162
Measles
psiu05163
Human cytomegalovirus infection
psiu05164
Influenza A
psiu05165
Human papillomavirus infection
psiu05166
Human T-cell leukemia virus 1 infection
psiu05167
Kaposi sarcoma-associated herpesvirus infection
psiu05168
Herpes simplex virus 1 infection
psiu05169
Epstein-Barr virus infection
psiu05171
Coronavirus disease - COVID-19
psiu05200
Pathways in cancer
psiu05203
Viral carcinogenesis
psiu05212
Pancreatic cancer
psiu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
116756336 (JAK1)
04151 PI3K-Akt signaling pathway
116756336 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
116756336 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
116756336 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
116756336 (JAK1)
04621 NOD-like receptor signaling pathway
116756336 (JAK1)
04658 Th1 and Th2 cell differentiation
116756336 (JAK1)
04659 Th17 cell differentiation
116756336 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
116756336 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116756336 (JAK1)
05203 Viral carcinogenesis
116756336 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116756336 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
116756336 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116756336 (JAK1)
05161 Hepatitis B
116756336 (JAK1)
05160 Hepatitis C
116756336 (JAK1)
05171 Coronavirus disease - COVID-19
116756336 (JAK1)
05164 Influenza A
116756336 (JAK1)
05162 Measles
116756336 (JAK1)
05168 Herpes simplex virus 1 infection
116756336 (JAK1)
05163 Human cytomegalovirus infection
116756336 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
116756336 (JAK1)
05169 Epstein-Barr virus infection
116756336 (JAK1)
05165 Human papillomavirus infection
116756336 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
116756336 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116756336 (JAK1)
05140 Leishmaniasis
116756336 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116756336 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
psiu01001
]
116756336 (JAK1)
Enzymes [BR:
psiu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116756336 (JAK1)
Protein kinases [BR:
psiu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
116756336 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
116756336
NCBI-ProteinID:
XP_032492507
Ensembl:
ENSPSNG00000003215
LinkDB
All DBs
Position
1:complement(56076457..56314893)
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTDVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNSYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
RFHPNDNGNILCYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILLTVT
CFEKSELLGVQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT
LMDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGTDSECGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSIRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatttaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagactgacgtgaatctggaggcccctgagccaggggtggaagtgctcttc
tatctgtcggacagggagcccctccgattgggcggcggagagtacacagcggaggagctg
tgcatcagggcggcgcaggaatgctgtatatctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgctccaaatcgcaccatcaccgtcgacgacaag
atgtcactcaggctccactaccggatgaggttctatttcaccaactggcacgggaccaat
gataacgagcagtcagtatggcgacattctccaaagaagcagaagaatagctacgagaaa
aaaaaagttccagatgcaacccctctccttgacgccagctcattggagtatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag
gatgggcatgatattgagaacgagtgtctgggaatggccgtcctggccatctcccactat
gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat
attccagaaacactgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgtgacagcagt
gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat
cggttccatccgaatgataatggaaacattctctgctatgaagtgatggtgactggaaat
cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaataaaatccgg
gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct
gtggtcagcattaataagcaggacaacaagaaaatggaactgaagctctcttcccacgag
gaggccttgtcctttgtgtccctcgtggacggctacttccggctcacagcagatgcccat
cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt
cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag
ggaatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcctgaccgtcact
tgctttgaaaagtctgagttgctgggtgtccagaagcagttcaagaactttcagattgag
gtgcagaagggccgctacagcctgcatggctcagaccgaagcttccccagccttggagac
ctcatgagccacctgaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaa
gatattatgcagggcgagcaccttgggagaggcacgcgaacacacatctactctgggacc
ctcatggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg
atgagacaggtctcccataaacacatcgtgtacctctatggcgtttgtgtccgagacgtg
gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg
aaaagtgatgtcctcaccacaccctggaagttcaaagttgccaaacagctggccagcgcc
ctgagttacttggaggataaagatctggtccacggaaatgtgtgcactaaaaacctcctc
ctggcccgcgagggcactgacagcgagtgcggccccttcatcaagctcagtgaccccggc
atccccgtcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctcct
gagtgtgttgaagactccaagaacctgagtgtggccgctgacaagtggagctttggaacc
acgctctgggagatctgctacaatggcgagatccccttgaaagacaagacactgattgag
aaagagaggttctatgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct
gaccttatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc
atgagagacatcaataagctggaggagcagaatccagacatcgtatcagaaaaaaagcca
gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg
ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca
ggggagcaggtggccgtcaaatccctgaagcccgagagcggagggaaccacatagctgat
ctgaagaaggaaattgaaatcttaagaaacctttatcatgagaacattgtgaagtataaa
ggcatctgcacagaagacggaggaaacggtattaagctcatcatggaatttctgccttca
ggaagtcttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcagtta
aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatacgttcac
cgtgacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggggac
tttggtctaaccaaagccattgaaactgataaggagtactacacagtcaaggacgatcgg
gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc
tctgatgtctggtcttttggagtaactctgcatgagctgcttacttactgtgattcagat
tccagtcccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagta
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca
gaagaggtttatcaacttatgagaaaatgctgggaattccaaccatccattcggacaacc
tttcagaaccttattgagggatttgaagcgcttctaaaataa
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integrated database retrieval system
