KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111536462
Entry
111536462         CDS       T07491                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh04010  MAPK signaling pathway
pteh04060  Cytokine-cytokine receptor interaction
pteh04068  FoxO signaling pathway
pteh04144  Endocytosis
pteh04218  Cellular senescence
pteh04350  TGF-beta signaling pathway
pteh04371  Apelin signaling pathway
pteh04380  Osteoclast differentiation
pteh04390  Hippo signaling pathway
pteh04520  Adherens junction
pteh04659  Th17 cell differentiation
pteh04926  Relaxin signaling pathway
pteh04933  AGE-RAGE signaling pathway in diabetic complications
pteh05142  Chagas disease
pteh05161  Hepatitis B
pteh05166  Human T-cell leukemia virus 1 infection
pteh05200  Pathways in cancer
pteh05210  Colorectal cancer
pteh05212  Pancreatic cancer
pteh05220  Chronic myeloid leukemia
pteh05225  Hepatocellular carcinoma
pteh05226  Gastric cancer
pteh05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111536462 (TGFBR1)
   04350 TGF-beta signaling pathway
    111536462 (TGFBR1)
   04390 Hippo signaling pathway
    111536462 (TGFBR1)
   04371 Apelin signaling pathway
    111536462 (TGFBR1)
   04068 FoxO signaling pathway
    111536462 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    111536462 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    111536462 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    111536462 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    111536462 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    111536462 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    111536462 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111536462 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111536462 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111536462 (TGFBR1)
   05212 Pancreatic cancer
    111536462 (TGFBR1)
   05225 Hepatocellular carcinoma
    111536462 (TGFBR1)
   05226 Gastric cancer
    111536462 (TGFBR1)
   05220 Chronic myeloid leukemia
    111536462 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111536462 (TGFBR1)
   05161 Hepatitis B
    111536462 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    111536462 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    111536462 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111536462 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pteh01001]
    111536462 (TGFBR1)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     111536462 (TGFBR1)
Protein kinases [BR:pteh01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   111536462 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 111536462
NCBI-ProteinID: XP_023058602
Ensembl: ENSPTEG00000026187
LinkDB
Position
14:complement(39969872..40020592)
AA seq 504 aa
MEAAAAAPRPRLLLLVLAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTD
KVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGPFSVKSSP
GLGPVELAAVIAGPVCFVCISLMLMVYICHSRTVIHHRVPNEEDPSLDRPFISEGTTLKD
LIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREE
RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTV
EGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHD
SATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGG
IHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANG
AARLTALRIKKTLSQLSQQEGIKM
NT seq 1515 nt   +upstreamnt  +downstreamnt
atggaggcggcggccgctgctccgcgtccccggctgcttctcctcgtgctggcggcggcg
gcggcggcgctgctcccgggggcgacggcattacagtgtttctgccacctctgtacaaaa
gacaattttacttgtgtgacagatgggctctgctttgtctctgtcacagagaccacagac
aaagttatacacaacagcatgtgtatagctgaaattgacttaattcctcgagataggcca
tttgtatgtgcaccctcttcaaaaactgggtctgtgactacaacatattgctgcaatcag
gaccattgcaataaaatagaacttccaactactggccctttttcagtaaagtcgtcacct
ggccttggtcccgtggaactggcagctgtcattgctggaccagtgtgctttgtctgcatc
tcactcatgttgatggtatatatctgccacagtcgcactgtcattcaccatcgagtgcca
aatgaagaggacccttcattagatcgcccttttatttcagagggtactacgttgaaagac
ttaatttatgatatgacaacatcaggttctggctcaggtttaccattgcttgttcagaga
acaattgcgagaactattgtgttacaagaaagcattggcaaaggtcgatttggagaagtg
tggcgaggaaagtggcggggagaagaagttgctgttaagatattctcttctagagaagaa
cgttcatggttccgtgaggcagagatttatcaaactgtaatgttacgtcatgaaaacatc
ctgggatttatagcagcagacaataaagacaatggcacttggactcagctctggttggtg
tcagattatcatgagcatggatccctttttgattacttaaacagatacacagttactgtg
gaaggaatgataaaacttgctctgtccacagcgagcggtcttgcccatcttcacatggag
attgttggtacccaaggaaagccagccattgctcatagagatttgaaatcaaagaatatc
ttggtaaagaagaatggaacttgctgtattgcagacttaggactggcagtaagacacgat
tcagccacagataccattgatattgctccaaaccacagagtgggaacaaaaaggtacatg
gcccctgaagttctcgatgattccataaatatgaaacattttgaatccttcaaacgtgct
gacatctatgcaatgggcttagtattctgggaaattgctcgacgatgttccattggtgga
attcatgaagattaccagctgccttattatgatcttgtaccttctgacccatcagtggaa
gaaatgagaaaagttgtttgtgaacagaagttaaggccaaatatcccaaacagatggcag
agctgcgaagccttgagagtaatggctaaaattatgagagaatgttggtatgccaacgga
gcagctaggcttacagcattgcggattaagaaaacattatcacaactcagtcaacaggaa
ggcatcaaaatgtaa

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