Pan troglodytes (chimpanzee): 469513 Help Entry 469513            CDS       T01005                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr00010   Glycolysis / Gluconeogenesis ptr00620   Pyruvate metabolism ptr01100   Metabolic pathways ptr01200   Carbon metabolism ptr01230   Biosynthesis of amino acids ptr04910   Insulin signaling pathway ptr04930   Type II diabetes mellitus ptr04932   Non-alcoholic fatty liver disease ptr04950   Maturity onset diabetes of the young Module ptr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ptr_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:ptr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     469513 (PKLR)    00620 Pyruvate metabolism     469513 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     469513 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     469513 (PKLR)    04950 Maturity onset diabetes of the young     469513 (PKLR)    04932 Non-alcoholic fatty liver disease     469513 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ptr04147]     469513 (PKLR) Enzymes [BR:ptr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      469513 (PKLR) Exosome [BR:ptr04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    469513 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  469513 NCBI-ProteinID:  XP_016784213 Ensembl:  ENSPTRG00000001421 VGNC:  48991 LinkDB All DBs Position 1:complement(130088807..130100953) Genome browser AA seq 585 aa AA seqDB search MVPQPQAHTESMSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQ ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG GPESDVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR KANDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS NT seq 1758 nt NT seq  +upstreamnt  +downstreamnt atggtcccgcagccccaggcccacactgaaagcatgtcgatccaggagaacatatcatcc ctgcagcttcggtcatgggtctctaagtcccaaagagacttagcaaagtccatcctgatt ggggctccaggagggccagcggggtatctgcggcgggccagtgtggcccaactgacccag gagctgggcactgccttcttccagcagcagcagctgccagctgctatggcagacaccttc ctggaacacctctgcctactggacattgactccgagcccgtggctgctcgcagtaccagc atcattgccaccatcgggccagcatctcgctccgtggagcgcctcaaggagatgatcaag gccgggatgaacattgcgcgactcaacttctcccacggctcccacgagtaccatgctgag tccatcgccaacgtccgggaggcggtggagagctttgcaggttccccactcagctaccgg cccgtggccatcgccctggacaccaagggaccggagatccgcactgggatcctgcagggg ggtccagagtcggacgtggagctggtgaagggctcccaggtgctggtgactgtggacccc gcgttccggacgcgggggaacgcgaacaccgtgtgggtggactaccccaatattgtccgg gtcgtgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtccag aaaatcggcccagagggactggtgacccaagtggagaacggcggcgtcctgggcagccgg aaaggcgtgaacttgccaggggcccaggtggacttgcccgggctgtccgagcaggacgtc cgagacctgcgcttcggggtggagcatggggtggacatcgtctttgcctcctttgtgcgg aaagccaacgacgtggctgccgtcagggctgctctgggtccggaaggacacggcatcaag atcatcagcaaaattgagaaccacgaaggcgtgaagaggtttgatgaaatcctggaggtg agcgacggcatcatggtggcacggggggacctaggcatcgagatcccagcagagaaggtt ttcctggctcagaagatgatgattgggcgctgcaacttggcgggcaagcctgttgtctgt gccacacagatgctggagagcatgattaccaagccccggccaacgagggcagagacaagc gatgtcgccaatgctgtgctggatggggctgactgcatcatgctgtcaggggagactgcc aagggcaacttccctgtggaagcggtgaagatgcagcatgcgattgcccgggaggcagag gccgcagtgtaccaccggcagctgtttgaggagctacgtcgggcagcgccactaagccgt gatcccactgaggtcaccgccattggtgctgtggaggctgccttcaagtgctgtgctgct gccatcattgtgctgaccacaactggccgctcagcccagcttctgtctcggtaccgacct cgggcagcagtcattgctgtcacccgctctgcccaggctgcccgccaggtccacttatgc cgaggagtcttccccttgctttaccgtgaacctccagaagccatctgggcagatgatgta gatcgccgggtgcaatttggcattgaaagtggaaagctccgtggcttcctccgtgttgga gacctggtgattgtggtgacaggctggcgacctggctccggctacaccaacatcatgcgg gtgctaagcatatcctga

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