Pyrococcus sp. ST04: Py04_0850
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Entry
Py04_0850 CDS
T02124
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pys
Pyrococcus sp. ST04
Pathway
pys00290
Valine, leucine and isoleucine biosynthesis
pys00660
C5-Branched dibasic acid metabolism
pys01100
Metabolic pathways
pys01110
Biosynthesis of secondary metabolites
pys01210
2-Oxocarboxylic acid metabolism
pys01230
Biosynthesis of amino acids
Module
pys_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pys00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Py04_0850
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Py04_0850
Enzymes [BR:
pys01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Py04_0850
4.2.1.35 (R)-2-methylmalate dehydratase
Py04_0850
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AFK22442
UniProt:
I3RDY2
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Position
855946..857217
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AA seq
423 aa
AA seq
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MGMTIAEKILAEHAGKEEVKPGEIVMAKLDFMLGNDVTTPLAIKKFRELGVERVFDPERI
AIVLDHFTPNKDIKAAEQCKFAREFAREQRIKYFFEGGNVGVEHCLLPELGLVLPGDLVI
GADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETMKFVYEGDLQPWVTGKDLIL
YTIGDIGVNGALYKVMEFSGEVIEKLSVEQRMTMTNMAIEAGAKTGIIEPDKKTIEYVKE
RAQRDWKIYRSDEDAKYYKVIEYKVENIEPQVAFPHLPENTVPISKAAKMDIKIDQVFIG
SCTNGRIEDLRMAAEVLEGQKVAPWVRLIIIPCSPSVYWKALKEGLLEIFLEAGAVIGPP
TCGPCLGGHMGVLASGERAVSTTNRNFVGRMGHPKSEVYLANPYVAAASAVLGRIASPEE
VVK
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgggcatgacaattgctgaaaagatcttagctgaacacgccggaaaagaagaagttaaa
ccgggagaaatagtgatggctaagcttgattttatgcttggcaacgatgtaacaactcca
ctagctattaaaaaattcagagagcttggggttgagcgggtatttgatcctgagagaata
gcaatagtcctcgatcattttaccccaaataaggatataaaagccgccgagcagtgtaag
tttgctagagaatttgcaagggaacagcggataaagtactttttcgagggaggaaacgtt
ggtgtggagcactgccttttaccagagctcggcttagtgcttccaggggatcttgtcata
ggagcagactcccacacctgtacctacggtgcactgggagcatttgcaactggagtgggg
agtactgatttggctgttgcaatggctactggtgaggcatggtttagagttccagaaact
atgaagttcgtctacgaaggagatcttcaaccctgggttacaggcaaagacttaatcctt
tacaccataggggacattggtgttaatggagctctctacaaggttatggagttcagtggt
gaagtgatagaaaagttatccgtagagcagagaatgacaatgacaaatatggctatagaa
gcgggtgcaaagacggggataattgaaccagataagaaaacgatagaatacgtaaaagaa
agggctcagagggattggaagatttacagaagtgatgaagatgctaagtactataaggtt
attgaatacaaggttgaaaatatagagccccaggtcgcatttcctcatctcccagagaac
acggttcccataagcaaggccgctaaaatggacataaaaattgaccaggtcttcataggg
tcgtgtactaatggaaggatagaagaccttagaatggcggctgaagtccttgagggtcaa
aaagttgccccctgggtaaggttaatcataatcccatgttcgccaagcgtttattggaag
gcactaaaagagggtcttctggaaatatttcttgaagcaggtgctgtcattggacctccc
acctgtggcccatgccttgggggccatatgggagtcttagcttctggggagagggcagtc
tccacaacaaacagaaactttgtaggaagaatgggacacccaaagagcgaggtttacctt
gcaaacccatacgttgcggctgcttctgctgtccttggaaggatagcttctcctgaggag
gtggtaaaatga
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