Puma yagouaroundi (jaguarundi): 121013826 Help Entry 121013826         CDS       T07555                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu04010   MAPK signaling pathway pyu04014   Ras signaling pathway pyu04015   Rap1 signaling pathway pyu04022   cGMP-PKG signaling pathway pyu04066   HIF-1 signaling pathway pyu04068   FoxO signaling pathway pyu04072   Phospholipase D signaling pathway pyu04150   mTOR signaling pathway pyu04151   PI3K-Akt signaling pathway pyu04152   AMPK signaling pathway pyu04211   Longevity regulating pathway pyu04213   Longevity regulating pathway - multiple species pyu04520   Adherens junction pyu04910   Insulin signaling pathway pyu04913   Ovarian steroidogenesis pyu04923   Regulation of lipolysis in adipocytes pyu04930   Type II diabetes mellitus pyu04931   Insulin resistance pyu04932   Non-alcoholic fatty liver disease pyu04960   Aldosterone-regulated sodium reabsorption pyu05010   Alzheimer disease pyu05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:pyu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     121013826 (INSR)    04014 Ras signaling pathway     121013826 (INSR)    04015 Rap1 signaling pathway     121013826 (INSR)    04066 HIF-1 signaling pathway     121013826 (INSR)    04068 FoxO signaling pathway     121013826 (INSR)    04072 Phospholipase D signaling pathway     121013826 (INSR)    04022 cGMP-PKG signaling pathway     121013826 (INSR)    04151 PI3K-Akt signaling pathway     121013826 (INSR)    04152 AMPK signaling pathway     121013826 (INSR)    04150 mTOR signaling pathway     121013826 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     121013826 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     121013826 (INSR)    04923 Regulation of lipolysis in adipocytes     121013826 (INSR)    04913 Ovarian steroidogenesis     121013826 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     121013826 (INSR)   09149 Aging    04211 Longevity regulating pathway     121013826 (INSR)    04213 Longevity regulating pathway - multiple species     121013826 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     121013826 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     121013826 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     121013826 (INSR)    04932 Non-alcoholic fatty liver disease     121013826 (INSR)    04931 Insulin resistance     121013826 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pyu01001]     121013826 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:pyu04090]     121013826 (INSR) Enzymes [BR:pyu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      121013826 (INSR) Protein kinases [BR:pyu01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    121013826 (INSR) CD molecules [BR:pyu04090]  Proteins   121013826 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Recep_L_domain PK_Tyr_Ser-Thr Furin-like Insulin_TMD Pkinase fn3 B2 DUF4476 Motif Other DBs NCBI-GeneID:  121013826 NCBI-ProteinID:  XP_040305567 LinkDB All DBs Position Unknown AA seq 1324 aa AA seqDB search MDAARRTESIFSGLAGGGRTTIEPYSRTAFAGHADTPGRWAARLRPPPVTPATEHTERPG RACTRLSPGPWRWAGAPARVYYEARRQDWDQDRGPERSGRSEGAPDPEVADGARAAAVRG RGRLRRIGEGAEREREAQSPKQALGSEPAAQSPTPALSQPGAPSAPDSYHPSATCVLTCL ALCLFSPLVCPGMDIRNNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLSFPKLVMIT DYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVR IEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQF VERCWTHGHCQKVCPTICKSHGCTADGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCV ETCPPPYYHFQDWRCVNFSFCWDLHNKCKNSRRQGCHQYVIHNNRCIPECPSGYTMNSSN LMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANL GLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHN LTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYI RTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPL RSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVP LDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRTW SPPFESEGSQKHNQSEYEESAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRP SRKRRALADAGNVTAAVPTVPGFPNTSSSVPTSPEEHKPFEKVVNKESLVISGLRHFTGY RIELQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPN GLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTE ATYFYVTDYYVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEY LSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTV NESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMVHGDLKSYLRSLR PEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGGLS GFLL NT seq 3975 nt NT seq  +upstreamnt  +downstreamnt atggacgctgcacggagaactgagagcatcttctcgggcctggcgggaggcgggcggacc accatcgagccctattcgcggacggcatttgctggacacgcagacacccccggacgctgg gccgcacgcctcaggccacctcccgtcacccctgccacggagcacaccgagcgccctggg cgcgcgtgcacgcggctgtccccagggccctggcgctgggcgggggcgcccgcgcgcgtc tactacgaggcgcgccggcaggactgggaccaggatcgcggcccagagcgctcggggcgc agcgagggggctccggacccggaggtcgcggacggggcccgggccgccgcggtccggggt cggggccgccttcgccggatcggggaaggggcagagagagagagggaggcacagagtccg aagcaggctctgggctccgagccggcagcacagagcccgacgccggctctgagccagccc ggcgccccgtctgcccctgactcttatcacccatccgcgacgtgcgtgctcacctgtctt gccttgtgcttgttttcgcctctagtctgccctggcatggatatccggaacaacctgacg aggctgcacgaactggccaactgctcggtcattgaaggtcatttgcagatactgctcatg ttcaaaacgaggcccgaggacttccgagacctcagtttccccaaactcgtcatgatcact gattacctgctgctcttccgggtgtacgggctggagagcctgaaggacctcttccccaac ctcacggtcatccggggctcgcgcctcttcttcaactacgcgctggtcatcttcgagatg gtgcacctgaaggagcttggcctctacagcttgatgaacattacccggggctccgtccgc atcgagaagaataatgaactgtgctacctggccaccatcgactggtcgcgcatcctggat tcggtggaggataattacattgtgttgaacaaagacgacaacgaggagtgtggggacatt tgtccaggcactgcaaagggcaagaccaactgccctgccactgtcatcaacgggcagttt gtggagcgttgttggacacacggccattgccagaaagtttgtccgaccatctgcaagtcg cacggctgcacggccgacggcctctgctgccacagcgagtgtttgggcaactgctccgag cccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctggacggcaggtgcgtg gagacctgcccgcccccctactaccacttccaagactggcgctgcgtgaacttcagcttc tgctgggacctgcacaataaatgcaagaactcccggagacagggttgccaccagtatgtc attcacaacaacaggtgcatccctgagtgcccctcggggtacacgatgaattccagcaac ctgatgtgtactccctgcctgggcccctgtcccaaggtctgccacatcctggaaggcgag aagaccatcgactcggtgacatctgcccaggagctccgaggctgcaccgtcgtcaacgga agcctaatcatcaacattcgagggggcaacaacctggcagctgagctggaggccaacctc ggactcattgaagaaatttccgggtatctgaagatccggagatcctatgctctcgtgtca ctttcctttttccggaagttacggctgattcggggagagaccttggaaatcgggaactac tctttctatgccttggacaaccagaacctgaggcagctatgggactggagcaaacacaac ctcaccatcactcaggggaaactcttcttccactataatcccaaactctgcttgtcggaa attcacaagatggaggaggtttcaggaaccaaggggcgccaggagcggaacgacattgcc ctgaagaccaatggggaccaggcgtcttgtgaaaatgaactacttaaattttcttacatt cggacatcttacgacaagatcttgctgaaatgggagccgtactggccccctgacttccga gacctccttggcttcatgctcttctacaaagaggccccttatcagaatgtgaccgagttc gacgggcaggacgcgtgtggctccaacagctggacggtggtggacattgacccacctctg aggtccaatgaccccaagtcgcagaaccacccagggtggctgatgcggggtctcaagccc tggacccagtatgccatctttgtcaagaccttggtcaccttttctgatgagcgccgcacg tatggggccaagagtgacatcatctatgtccagaccgatgccaccaacccttccgtcccc ctggatcctatctcggtttcgaattcctcctctcagatcattctgaagtggaagcctccc tcggaccccaatggcaacatcacgcactacctggtgttctgggagaggcaggcggaggac agcgagctgtatgagttggattattgcctcaaagggttgaagctgccttcccggacctgg tccccgccgttcgagtccgagggctcccagaagcacaatcagagtgagtacgaggagtcc gctggcgaatgctgctcgtgtcccaaaaccgactctcagatcctgaaggagctggaggag tcctctttcaggaagacgttcgaggattacctgcacaatgtggttttcgtgcccaggccg tcgcggaagcgcagggccctcgccgacgctgggaacgtgacggccgccgtgcccacggtg cctggtttccccaacacttccagcagtgtgcccacgagcccggaagagcacaagcccttc gagaaggtggtgaacaaagagtcgctggtcatctccggcctgcgtcacttcaccggctac cgcatcgagctgcaggcttgcaaccaagatgcccccgaggagaggtgcagcgtggctgcc tacgtcagcgccaggaccatgcccgaagccaaggcagacgacattgttggccctgtgacc catgaaatcttcgagaacaacgtggttcacttgatgtggcaagagcctaaagaacccaat ggattgatcgtgctgtatgaagtgagttaccgacggtatggtgatgaggagctgcacctc tgtgtctcccgtagacactttgctctggagcggggctgcaggctgcgagggctgccgcca gggaattacagtgtgcgagttcgggccacctccctggcgggcaacggctcctggacagaa gccacttatttctatgtgacagactattatgtcccatcgaacattgcaaaaattatcatc gggcctctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctg agaaagaggcagccggatggcccactggggccgctgtatgcttcttcaaaccctgagtac ctcagtgccagtgatgtgtttccctgctctgtgtatgtgccggacgagtgggaggtgcct cgggagaagatcaccctcctgcgcgagctggggcagggctccttcggcatggtgtacgag ggcaatgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtc aacgagtctgccagtctgcgagagaggatcgagtttctcaacgaggcctcagtcatgaag ggcttcacctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccgacg ctggtggtgatggagctgatggttcacggagacctgaagagctacctccgctccctgcgg ccggaggctgagaataaccctggccgccctccccctactctgcaagagatgattcagatg gcggcggagatcgccgacgggatggcgtacctgaatgccaagaagtttgtgcaccgggat ctcgcagctcgaaattgcatggtggcccacgacttcaccgtcaaaattggaggtttgtcc ggctttctgctttga

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