KEGG   Rousettus aegyptiacus (Egyptian rousette): 107516161
Entry
107516161         CDS       T06036                                 
Symbol
GSTM4
Name
(RefSeq) glutathione S-transferase Mu 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00480  Glutathione metabolism
ray00980  Metabolism of xenobiotics by cytochrome P450
ray00982  Drug metabolism - cytochrome P450
ray00983  Drug metabolism - other enzymes
ray01100  Metabolic pathways
ray01524  Platinum drug resistance
ray05200  Pathways in cancer
ray05204  Chemical carcinogenesis - DNA adducts
ray05207  Chemical carcinogenesis - receptor activation
ray05208  Chemical carcinogenesis - reactive oxygen species
ray05225  Hepatocellular carcinoma
ray05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ray00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    107516161 (GSTM4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    107516161 (GSTM4)
   00982 Drug metabolism - cytochrome P450
    107516161 (GSTM4)
   00983 Drug metabolism - other enzymes
    107516161 (GSTM4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107516161 (GSTM4)
   05204 Chemical carcinogenesis - DNA adducts
    107516161 (GSTM4)
   05207 Chemical carcinogenesis - receptor activation
    107516161 (GSTM4)
   05208 Chemical carcinogenesis - reactive oxygen species
    107516161 (GSTM4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    107516161 (GSTM4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    107516161 (GSTM4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    107516161 (GSTM4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ray02000]
    107516161 (GSTM4)
Enzymes [BR:ray01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     107516161 (GSTM4)
Transporters [BR:ray02000]
 Other transporters
  Pores ion channels [TC:1]
   107516161 (GSTM4)
SSDB
Motif
Pfam: GST_N GST_C GST_C_3 GST_N_3 GST_C_6 GST_N_2 GST_C_2
Other DBs
NCBI-GeneID: 107516161
NCBI-ProteinID: XP_016011135
LinkDB
Position
Unknown
AA seq 218 aa
MTMTLGYWDIRGLAHAIRLLLEYTDSDYEEKKYTMGDAPDYDRSQWLREKFKLGLDFPNL
PYLMDGAHRLTQSNAILRYLARKHNLCGETEEEKIYVDILENQVMDVSNELARVCYSPDF
EKLKPEFLSALPEKLKLFSQFLGKRPWFVGGKLTYVDFLAYDMLDLHRIFEPKSLDAFPN
LTDFVVRFEGLEKISAYMKSSRFIPGPLFLKIAVWGNK
NT seq 657 nt   +upstreamnt  +downstreamnt
atgaccatgactttgggttactgggatatccgtgggctggctcacgccatccgcctgctc
ctggagtacacggactccgactacgaggagaagaagtacacgatgggggacgctcccgac
tatgacaggagccagtggctgagggaaaaattcaagctgggcctggacttccccaatctg
ccctacttaatggacggggctcacaggctcacccagagcaacgccatcctccgctacctt
gctcgcaagcacaacctatgtggagagacggaagaggagaagatttacgtggacattttg
gagaatcaggttatggacgtatccaatgaactggccagagtctgctatagccctgacttt
gagaaactgaagccggagttcttgagcgcactccctgaaaagctgaagctcttctcgcag
tttctggggaagaggccttggtttgtagggggcaagctcacctatgtggatttcctggct
tatgacatgctagacctgcatcgtatatttgagcccaagagcctggacgcattcccaaac
ctgacagactttgtggtccgcttcgagggcctggagaagatctctgcctacatgaagtcc
agccgcttcatcccaggtcctctgtttcttaaaattgcagtgtggggcaacaaatag

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