Rousettus aegyptiacus (Egyptian rousette): 107519908
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Entry
107519908 CDS
T06036
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010
MAPK signaling pathway
ray04014
Ras signaling pathway
ray04015
Rap1 signaling pathway
ray04022
cGMP-PKG signaling pathway
ray04066
HIF-1 signaling pathway
ray04068
FoxO signaling pathway
ray04072
Phospholipase D signaling pathway
ray04150
mTOR signaling pathway
ray04151
PI3K-Akt signaling pathway
ray04152
AMPK signaling pathway
ray04211
Longevity regulating pathway
ray04213
Longevity regulating pathway - multiple species
ray04520
Adherens junction
ray04910
Insulin signaling pathway
ray04913
Ovarian steroidogenesis
ray04923
Regulation of lipolysis in adipocytes
ray04930
Type II diabetes mellitus
ray04931
Insulin resistance
ray04932
Non-alcoholic fatty liver disease
ray04960
Aldosterone-regulated sodium reabsorption
ray05010
Alzheimer disease
ray05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107519908 (INSR)
04014 Ras signaling pathway
107519908 (INSR)
04015 Rap1 signaling pathway
107519908 (INSR)
04066 HIF-1 signaling pathway
107519908 (INSR)
04068 FoxO signaling pathway
107519908 (INSR)
04072 Phospholipase D signaling pathway
107519908 (INSR)
04022 cGMP-PKG signaling pathway
107519908 (INSR)
04151 PI3K-Akt signaling pathway
107519908 (INSR)
04152 AMPK signaling pathway
107519908 (INSR)
04150 mTOR signaling pathway
107519908 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
107519908 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
107519908 (INSR)
04923 Regulation of lipolysis in adipocytes
107519908 (INSR)
04913 Ovarian steroidogenesis
107519908 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
107519908 (INSR)
09149 Aging
04211 Longevity regulating pathway
107519908 (INSR)
04213 Longevity regulating pathway - multiple species
107519908 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
107519908 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107519908 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
107519908 (INSR)
04932 Non-alcoholic fatty liver disease
107519908 (INSR)
04931 Insulin resistance
107519908 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107519908 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ray04090
]
107519908 (INSR)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107519908 (INSR)
Protein kinases [BR:
ray01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
107519908 (INSR)
CD molecules [BR:
ray04090
]
Proteins
107519908 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
Motif
Other DBs
NCBI-GeneID:
107519908
NCBI-ProteinID:
XP_016018572
LinkDB
All DBs
Position
Unknown
AA seq
1378 aa
AA seq
DB search
MGAAGRRGLAAAPLLVAVAALLVGAAGHLYPGEVCPSMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPGDPTKCTACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCLHLHDKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLAFFRKLRLIRGDTL
EVGNYSFYALDNQNLRQLWDWSKHHLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSNIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQSHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVSWE
RQAEDSELYELDYCLKGLKLPSRTWSPPSESEGSQKHNQSEYDDAAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKSSAGPGAEDSRPSRKRRALGDMENVTTVAPTAPSF
PNTSWTSVPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYSDEELHLCV
SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMTHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMS
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMEGGYLDQPEN
CPERLTELMRMCWQFNPKMRPAFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMESVPLDRSSHSQREEDGGSTLGLKRNYEDHVPYTHMNGGKKNGRVLTLPRSSPS
NT seq
4137 nt
NT seq
+upstream
nt +downstream
nt
atgggcgctgcgggcaggcggggcttggccgcggcgccgctgctggtggccgtggccgcg
ctgctggtgggcgctgcgggccatctgtatcccggagaggtgtgtcccagcatggatatc
cggaacaatctcacgaggctgcacgagctggccaactgctcagtcatcgaaggacatttg
cagatactgttgatgttcaaaacgaggcctgaggacttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctgttccgggtctacgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcccgtctcttcttcaactatgcgctg
gtcatctttgagatggttcacctgaaggagcttggcctctacagcctgatgaacatcacc
cggggctctgtccgtattgagaagaacaatgagctctgttacctggccaccatcgactgg
tcacgcatcctggattcggtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatctgtccaggcactgcaaagggcaaaaccaactgccctgccaccgtc
atcaatgggcagtttgtggagcggtgttggactcatagccattgccagaaagtctgcccg
accatctgtaaatcgcacggctgcaccgccgaaggcctctgctgccacagcgagtgcctg
ggcaactgctctgagcctggcgaccccaccaagtgcacagcctgccgcaacttctacctg
gacggccggtgtgtggagacctgcccacctccgtactaccacttccaggactggcgttgc
gtgaacttcagcttctgcctgcacctgcatgacaaatgcaagaactctcggaggcagggc
tgccaccagtatgtcatccacaataacaagtgcatccctgaatgtccctccggatacacg
atgaattccagcaacctgatgtgcactccgtgtctgggcccctgtcccaaggtctgtcac
ctcctggaaggcgagaagaccatcgactcggtgacgtccgcccaggagctccgaggctgc
actgtcatcaatgggagccttatcatcaacattcgagggggcaataatctggcagctgag
ctggaggccaacctcggcctcattgaagaaatttcagggtatctgaaaatccgccgttcc
tacgccctcgtgtcacttgccttcttccggaagctgcgtctgattcggggggataccttg
gaagtcgggaactactctttctatgccttggacaaccagaacctgaggcagctgtgggac
tggagcaaacaccacctcaccatcactcaggggaaactgtttttccactataatcccaaa
ctctgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaatggggaccaggcatcctgtgaaaatgaattactt
aaattttctaacattcggacatcttttgacaagatcttgctgaaatgggagccgtactgg
ccgccggacttccgagacctcctaggcttcatgctgttctacaaagaggccccttatcag
aatgtgacagagttcgatgggcaggatgcgtgtggctccaacagctggacggtggtggac
attgacccacctctgaggtccaatgacccgaagtcacagagccaccccgggtggctgatg
cggggtctgaagccctggacccagtatgccatcttcgtcaagaccttggtcaccttttct
gatgaacgtcgcacatatggggccaagagcgacatcatctatgtccagacagatgccacc
aatccttctgtccccctggaccccatctccgtttccaactcctcatcccagatcatcctg
aagtggaagcctccttctgaccccaacggcaacatcactcactacctggtttcgtgggag
aggcaggcagaggacagtgagctgtacgagctggattattgcctcaaagggctgaagctg
ccctcccggacctggtctccgccatcggagtcggagggttcccagaagcacaaccagagt
gagtacgatgatgccgcgggcgaatgctgttcctgccccaagaccgactctcagatcctg
aaggagctggaggagtcgtcgttccggaagacgttcgaggactacctgcacaatgtggtt
ttcgtccccagaaaatcctctgcaggccctggtgctgaggacagtaggccatcgaggaag
cgcagggcccttggcgatatggagaatgtgacgacagtcgcacccacggccccgagtttt
cccaacacctcctggaccagcgtgcccacgagctcggaggagcaccggcccttcgagaaa
gtggtgaacaaagagtcgctggtcatctccggcctgcgccacttcactggctatcgcatt
gagctgcaggcttgcaaccaggatgcccccgaggaaaggtgcagcgtagcagcctacgtc
agcgccaggaccatgcccgaagccaaggcagatgacattgttggccccgtgacccacgaa
atcttcgagaacaacgtcgttcatctgatgtggcaggagccgaaggaacccaacggtctg
attgtgctgtacgaagtgagttatcgacgatatagtgatgaggagctgcacctctgcgtc
tcccgcaggcatttcgctttggagcggggctgcaggctgcgtgggctgcccccagggaat
tacagcgtgcgagtgcgggccacctccctggcaggcaatggctcctggacggaagccacc
tatttctacgtgacagactacctagatgtcccatcaaacattgcaaaaattatcatcggt
cccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctgttcctgagg
aaaaggcagccagatgggcccctgggacctctgtatgcttcttcaaaccccgagtacctc
agtgccagcgatgtgttcccatgttctgtgtatgtgccggacgagtgggaagtgcctcgg
gagaagatcaccctcctgcgagagctggggcagggctccttcggcatggtgtacgagggc
aacgccaaggacatcatcaagggtgaggcagagacccgggtggcagtgaagacagtcaac
gagtcggccagcctgcgtgagcggatcgagtttctcaacgaggcctcggtcatgaagggc
ttcacctgccatcacgtggtccgcctcctgggggtggtgtccaaggggcagccgacactg
gtggtgatggagctgatgacccacggagacctgaagagctaccttcgttccctgcgaccc
gaggctgagaacaaccctggccgccctcccccgactctgcaagagatgatccagatgtca
gcagagatcgcggatgggatggcgtacctgaatgccaagaagttcgtgcaccgggacctc
gcagctcgaaactgcatggttgcccatgatttcactgttaaaattggagactttggaatg
accagagacatctatgagacggattactaccggaaagggggcaagggcctgctccctgtg
cggtggatggcgccggaatccctgaaggacggagtcttcactgcttcttcagacatgtgg
tccttcggcgtggtcctctgggaaatcaccagcttggcagaacagccttaccaaggcctg
tctaatgagcaggtgttgaaatttgtcatggaaggagggtatctggatcaacctgaaaat
tgtccggagagactcaccgagctgatgcgcatgtgctggcagttcaaccccaagatgcgg
ccagccttcctggagatcgtcgacctgctcaaggacgacctgcatcccagctttccagaa
gtttccttcttccatagtgaggagaacaaggcgcctgagagcgaggagttggagatggag
tttgaggacatggagagcgtgcccctggaccggtcctcacactctcagagggaagaggac
ggagggtccacgctgggcctgaagcggaattatgaggatcatgtcccctacacccacatg
aacgggggcaagaaaaacgggcgggtcctgactctgccacgctccagtccttcctaa
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integrated database retrieval system
