Prescottella equi: REQ_37620
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Entry
REQ_37620 CDS
T01352
Symbol
hemD
Name
(GenBank) secreted uroporphyrinogen-III synthase HemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
req
Prescottella equi
Pathway
req00860
Porphyrin metabolism
req01100
Metabolic pathways
req01110
Biosynthesis of secondary metabolites
req01120
Microbial metabolism in diverse environments
req01240
Biosynthesis of cofactors
Module
req_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
req_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
req00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
REQ_37620 (hemD)
Enzymes [BR:
req01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
REQ_37620 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
REQ_37620 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CBH49749
UniProt:
A0A3S5YB63
LinkDB
All DBs
Position
complement(4005323..4006888)
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AA seq
521 aa
AA seq
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MSRVRKNSPGRILFVGSGPGDPALLTVRAHDVLASAALAFTDPDVDKGVTALVGTALGRD
PETDLPIAEVRPALGEPAEVAKTLVAEAKNGHDVVRLVSGDPLTTDSVIAEVSAVARTQV
VFEVLPGLPSGSAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSAHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNDAGSELVGPLIVTVGKVVSQRNKM
SWWESRALYGWTVLVPRTKEQAADMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEAFGLDARAFSGVKIACVGEATAEKVRSFGITPELVP
SGEQSSEGLLADFPPYDEVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLR
VDVQPETAQMGPLVEALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgtaagaacagccccggacggatcctctttgtgggatcgggacccggt
gatccggcgctgctcaccgtccgcgcgcacgacgtgctcgcgtcggccgcgctggcgttc
accgatcccgacgtggacaagggcgtgaccgcgctcgtcggcaccgcgctcggccgcgac
ccggagaccgatctgccgatcgccgaggtccgccctgcgctgggcgagcccgccgaggtc
gccaagaccctcgtcgccgaggccaagaacggccacgacgtggttcggctcgtctcgggt
gacccgttgaccaccgactcggtgatcgccgaggtttcggccgtcgcccgcacccaggtc
gtgttcgaggtgctgcccggtctgccgtccggatccgccgtccccagctacgccggcatg
gcgctgggctcgggccacaccgaggccgacgtgcgcggcgaggtcgactgggccgcgctg
gccgccgcccccggcccgctggtgctgcacgcgacgtccgcgcacctggccgagacggcg
agcgcgctggtcgaacacggcctcgccccgcagaccccggccgcgatcaccgtccgcggc
accacccgtcagcagcgcaccgtcgaggccacccttgcgacgctcaacgacgctggttcc
gagctggtgggtccgctgatcgtcacggtcggcaaggtggtctcgcagcgcaacaagatg
tcgtggtgggagtcgcgcgcactgtacggctggaccgtcctggtgccgcgcaccaaggag
caggccgccgacatgagcgaccgcctcgtcacgcacggcgccatcccgatcgaggtgccg
accatcgcggtcgagccgccccgcagcccggcgcagatggagcgctcggtcaagggtctg
gtcgacggccgctaccagtgggtggtgttcacctccaccaacgcggtccgcgcggtgtgg
gagaagttcgaggccttcggtctggacgcccgcgcgttctccggcgtgaagatcgcgtgc
gtcggtgaggccacggccgagaaggtgcgctcgttcggcatcacccccgaactggtcccg
tcgggtgagcagtccagcgagggcctgctggccgacttccccccgtacgacgaggtgttc
gacccggtcaaccgcgtcctgctgccccgcgccgacatcgccaccgagacgctcgccgag
ggtctgcgcgagcgcggctgggagatcgacgacgtcaccgcgtaccgcaccgtccgggcg
gcaccgccgccggccgagacccgcgagatgatcaagacgggtggcttcgacgcggtgtgc
ttcacgtcgtcgtcgaccgtgcgcaacctggtcggcatcgccggcaagccgcacgcccgc
acgatcgtcgcgtgcatcgggcccaagaccgcggagaccgcgatcgagttcggtctgcgc
gtcgacgtccagccggagacggcgcagatgggaccgctcgtcgaggcactggccgagcat
gcggcccggctgcgcgccgagggcgcgctgccgcctccgcgtaagaagtcccgcgcccgc
cgctga
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