Rhodococcus sp. p52: IM25_01185
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Entry
IM25_01185 CDS
T05434
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rhq
Rhodococcus sp. p52
Pathway
rhq00860
Porphyrin metabolism
rhq01100
Metabolic pathways
rhq01110
Biosynthesis of secondary metabolites
rhq01120
Microbial metabolism in diverse environments
rhq01240
Biosynthesis of cofactors
Module
rhq_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rhq_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rhq00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
IM25_01185
Enzymes [BR:
rhq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
IM25_01185
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
IM25_01185
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AOD20422
UniProt:
A0A1B2U8F1
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Position
complement(285065..286630)
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AA seq
521 aa
AA seq
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MSRVRKHNPGRILFVGSGPGDPALLTVRARDVLAGATIAFTDPDVDKGVVALVGVDHGTD
PETGEPVAEVRPALGEPAEVAKTLVAEAKAGRDVVRLVAGDPLTTDSVIAEVNAVARTQV
VFEVLPGLPAGSSVPSYAGMALGSCHTEVDVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQPPAAITVRGTTRQQRTVEATLATLNDAGSELVGPLVVTVGKVVSHRNKM
SWWESRALYGWTVLVPRTKDQAGEMSERLVTHGAIPMEVPTIAVEPPRSPAQMERAVKGL
VDGRYQWVVFTSTNAVRAVWEKFEAFGLDARAFSGVKIACVGEATAAKVRSVGIIPELVP
SGEQSSLGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAATREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEFGLR
VDVQPETAQIGPLVDALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgtaagcacaaccccgggcgcatcctgttcgtgggatcgggcccgggc
gatcctgcgctgctcaccgtgcgcgcgcgtgacgtgctggcgggcgccacgatcgccttc
accgaccccgatgtcgacaagggtgtcgtggccctcgtcggtgtcgaccacggcaccgac
ccggagaccggtgagcccgtcgccgaggtccgtcccgcgctcggcgagcccgccgaggtc
gccaagacgctcgtcgccgaggcgaaggccggtcgcgacgtggtgcgcctcgtcgcgggc
gacccgctcaccaccgactcggtgatcgccgaggtcaacgcggtcgcccgcacccaggtg
gtcttcgaagtcctgccgggcctgcccgccggatcgtccgtgccgagctacgccggtatg
gcgctcggctcgtgccacaccgaggtcgacgtgcgcggagaggtcgactgggccgcgctc
gccgccgcccccggccccctcgtcctccatgcgacctccggccacctcgccgagaccgcc
agcgcgctggtcgaacacggcctggcgccgcagccccccgccgcgatcacggtgcgcggc
accacccgtcagcagcgcaccgtcgaggccaccctcgcgaccctgaacgacgcgggttcc
gagctcgtcggaccgctcgtcgtcaccgtcggcaaggtcgtctcgcaccgcaacaagatg
tcgtggtgggagtcgcgcgccctgtacggctggaccgtgctcgtgccccgcaccaaggat
caggccggcgagatgagcgagcggctcgtcacgcacggcgcgatcccgatggaggtgccg
accatcgcggtcgagccgccgcgcagtcccgcgcagatggaacgcgcggtcaagggcctg
gtcgacggtcgctaccagtgggtggtgttcacttccaccaacgcggtgcgtgcggtgtgg
gagaagttcgaggcgttcggtctcgacgcgcgcgcgttctccggcgtcaagatcgcgtgc
gtcggtgaggccaccgctgcgaaggtgcgctcggtcggcatcatccccgagctcgtgccc
agcggcgaacagtccagcctcggcctgctggccgagttcgccccgtacgacgacgtcttc
gatccggtcaaccgggtgctgctgccgcgcgccgacatcgccaccgagaccctcgccgag
ggtctgcgcgagcgcggctgggagatcgacgacgtcaccgcctaccgcaccgtgcgtgcc
gctccgccgccggccgcgacccgcgagatgatcaagaccggtggtttcgacgcggtgtgc
ttcacctcgtcgtcgacggtccgcaatctcgtgggtatcgccggcaagccgcacgcccgc
acgatcgtcgcgtgtatcggcccgaagacggccgagacggcgatcgagttcggcctgcgg
gtggacgtgcagcccgagaccgcgcagatcgggcccctggtcgacgcgctcgccgagcac
gcggcccggctccgcgcggaaggcgcactgcctccgccgcggaagaagtcccgcgcccgc
cgctga
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