Rhodococcus koreensis: JWS14_10475
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Entry
JWS14_10475 CDS
T07497
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
rko
Rhodococcus koreensis
Pathway
rko00860
Porphyrin metabolism
rko01100
Metabolic pathways
rko01110
Biosynthesis of secondary metabolites
rko01120
Microbial metabolism in diverse environments
rko01240
Biosynthesis of cofactors
Module
rko_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
rko_M00925
Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
rko_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
rko00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
JWS14_10475
Enzymes [BR:
rko01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
JWS14_10475
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
JWS14_10475
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QSE79541
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Position
complement(2245234..2246799)
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AA seq
521 aa
AA seq
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MSRVRKNTPGRILFVGSGPGDPALLTVHARDVLAAATLAFTDPDVDKGVTVLVGTDLGVD
AETGEPLAEVRPALGEPAEVAKTLVHEARNGHDVVRLVSGDPLTTDSVIAEVTAVARTQV
QFEVLPGLPSASAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNEAGSELVGSLVVTVGKVVAQRNKM
SWWESRALYGWKVLVPRTKDQAGEMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEEFGLDARAFSGVKIACIGEATAAKVRSFGINPELVP
SGEQSSEGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAIEFGLR
VDVQPETAQVGPLVEALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgtaagaacacccccggacgaatcctgttcgtgggatccggaccgggc
gatccggcactgctcaccgtgcacgcacgggacgtccttgccgcagccaccctcgccttc
accgaccccgacgtcgacaagggcgtcaccgttctggtgggcaccgacctgggcgtcgac
gccgagaccggtgagccgctcgccgaggtccgtcccgcactgggggagccggcggaggtc
gcgaagaccctcgtccacgaggcgaggaacggccacgacgtcgtgcgtctggtgtccggc
gacccgctgaccaccgactccgtgatcgccgaggtcaccgccgtcgcccgcacccaggtg
cagttcgaggtcctgccgggcctgccgtccgcgtccgccgtcccctcctacgccggtatg
gcactggggtcgggacacaccgaggccgacgtccgcggcgaggtcgactgggcagccctg
gccgccgcacccggaccgctggtcctgcacgccacgtcgggccacctcgccgagacggcg
agcgccctcgtcgagcacggtctggccccgcagaccccggccgccatcactgtccgcggc
accacccgccagcagcgcacggtggaagccaccctcgcgacgctgaacgaggccggttcg
gaactggtcggttcgctggtcgtgacggtcggcaaggtcgtcgcccagcgcaacaagatg
tcctggtgggagtcgcgcgcgctgtacggctggaaggtcctggtgccgcgcaccaaggat
caagcaggcgagatgagcgaccgcctcgtcacccacggcgccatcccgatcgaggtgccc
accatcgccgtcgagccgccccgcagcccggcacagatggaacggtccgtgaagggcctc
gtcgacggccgctaccagtgggtggtcttcacctccaccaacgcggtgcgtgcggtgtgg
gagaagttcgaggagttcgggctcgacgcccgcgcgttctccggcgtcaagatcgcctgc
atcggcgaggccaccgcagccaaggtgcgctcgttcggaatcaaccccgaactcgtgccg
tccggtgagcagtcgagcgaaggcctgctggccgaattcgccccgtacgacgatgttttc
gacccggtcaaccgggttctgctgccccgcgccgacatcgccaccgagacgctcgccgag
ggcctgcgcgaacgcggctgggaaatcgacgacgtcaccgcgtaccgcaccgtccgggct
gcgccgccgccggccgagacccgcgagatgatcaagaccggtgggttcgacgccgtctgc
ttcacctcgtcctcgacggtccgcaacctcgtcggtatcgccggaaagccgcacgcgcgc
accctcgtcgcctgcatcggtcccaagaccgccgagacggccatcgagttcggtctgcgc
gtggacgtgcagccggagaccgctcaggtcggcccgctggtggaggctctcgcagagcac
gccgcgcgcctgcgcgccgagggcgcactgcccccgccgcgcaagaagtcccgcgctcgg
cgatag
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