Ruminococcus lactaris: NQ541_03570
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Entry
NQ541_03570 CDS
T08757
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
rlr
Ruminococcus lactaris
Pathway
rlr00290
Valine, leucine and isoleucine biosynthesis
rlr00660
C5-Branched dibasic acid metabolism
rlr01100
Metabolic pathways
rlr01110
Biosynthesis of secondary metabolites
rlr01210
2-Oxocarboxylic acid metabolism
rlr01230
Biosynthesis of amino acids
Module
rlr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rlr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NQ541_03570 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NQ541_03570 (leuC)
Enzymes [BR:
rlr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NQ541_03570 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NQ541_03570 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
DUF2783
Motif
Other DBs
NCBI-ProteinID:
UWP66197
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Position
758262..759536
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AA seq
424 aa
AA seq
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MGMTMTQKILAAHAGLDSVEAGQLIEAKLDIVMANDITGPMALPILKQMSDTVFDKDKVV
FVPDHFTPNKDIKSAENSKAIREFSKAQGLKWYFEQGKSGVEHAILPEAGVVTAGECIIG
ADSHTCTYGALGAFSTGMGTTDVATGMATGEIWFKVPSAIKFVLTGKPSKYVSGKDIIIH
IIGQIGVDGALYKSMEFTGDGIACLSMDDRFTMANMAIEAGAKNGIFPVDEKTKAYLAEH
CKKEYTVYEADEDAVYDEVIEIDLSKVRPTVAFPHLPGNAKTIDEVEAMEPIKIDQVVIG
SCTNGRMEDLRKAAAILKGHTVHPDVRVMVIPATQKIYKECIKEGLLDIFVDAGCAVNTP
SCGPCMGGHMGVMAAGEKCVSTTNRNFVGRMGHVDSLIYLASPEVAAASAIAGCIANPEK
VGEK
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacaatgacgcagaaaattttagcagcccatgccggactggattccgtagag
gcagggcagctcatcgaggcgaagctcgatattgttatggcaaatgatattacaggaccg
atggctctgccaatcttaaagcagatgtcagatactgtatttgataaggataaagtagtg
tttgtaccggatcattttactccgaacaaagatatcaagtcagcagagaactccaaggca
atccgggagttctcaaaggcacagggactgaaatggtattttgaacagggaaaatccggt
gtagaacatgcgattctcccagaggcaggtgtagtgacagcaggtgaatgtattatcggt
gcagattcacatacctgtacatacggagctttgggagcattttcaacaggtatgggaaca
accgacgtggcaacaggaatggcaaccggtgagatctggtttaaagttccgagtgcaatc
aagtttgtcctgacaggaaagccgtccaaatatgtcagcggtaaagacattattatccat
atcatcggtcagatcggagtggatggagctctttacaaatcaatggaatttaccggagac
ggaattgcctgtctttcgatggatgaccgttttacgatggcaaatatggcgatcgaggct
ggtgcaaagaacggaatcttcccggttgacgaaaagacaaaagcttatcttgcagagcat
tgcaagaaagaatatacagtttatgaggctgatgaggatgcggtttatgatgaagtgatc
gaaatagatctttctaaagtacgcccgacagttgctttcccacatcttccgggaaatgca
aagacaattgatgaagttgaggcaatggaaccaattaagattgatcaggttgtgatcggt
tcctgcacgaacggaagaatggaagatttaagaaaggcagcagcgatcctgaaaggtcat
actgttcacccggatgtacgtgttatggttattccggcaacgcagaagatctataaagag
tgtatcaaagaaggacttcttgatatctttgtagatgcaggctgtgcagtgaatacacca
agctgtggtccctgcatgggtggccatatgggtgttatggcagcaggagaaaaatgtgtt
tctacaacaaaccgtaactttgtaggtcgtatgggacatgtggattccctgatctatctt
gcatcaccggaagtggcagcggcaagtgcaatcgcaggatgcattgcaaatccggagaaa
gtgggtgaaaagtaa
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