Cupriavidus metallidurans: Rmet_4273
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Entry
Rmet_4273 CDS
T00351
Symbol
leuC
Name
(GenBank) isopropylmalate isomerase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
rme
Cupriavidus metallidurans
Pathway
rme00290
Valine, leucine and isoleucine biosynthesis
rme00660
C5-Branched dibasic acid metabolism
rme01100
Metabolic pathways
rme01110
Biosynthesis of secondary metabolites
rme01210
2-Oxocarboxylic acid metabolism
rme01230
Biosynthesis of amino acids
Module
rme_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rme00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Rmet_4273 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Rmet_4273 (leuC)
Enzymes [BR:
rme01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Rmet_4273 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
Rmet_4273 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ABF11139
UniProt:
Q1LFD7
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Position
megaplasmid:863774..865207
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AA seq
477 aa
AA seq
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MVQANPPASLLDKLWASHVIHEQSDGPSLIYIDRHLVNEVTSPQAFEGLRLHGREVWRPA
SVLATADHNVPTTERAAGIADPISRAQVDALERNCAATGIVNFGMNDPRQGILHVVGPER
GATLPGMTIVCGDSHTSTHGAFGAFAFGIGTSEVEQVLSAQCLWMKKPRSMLVRVEGELA
AGVSAKDIALALIGRIGTAGATGYVIEFAGSTIRGLSMEGRMTVCNMAIEAGARAGMVAV
DETTLAYLAHRPQAPQGEAWESASAYWRTLRSDPDAVFDAVVDIGVATIRPHVTWGTSPE
MVVAIDERIPDPRQEADPVRRRGMERALTYMGLEPGIKVASIALDKVFIGSCTNARLEDL
RAAADVLRGRHVASNIRQALVVPGSGLVKSQAEAEGLDRVFIDAGFEWREPGCSMCLGMN
DDRLAPGERCASTSNRNFEGRQGPGGRTHLVSPQMAAAAAVAGHFVDVSTVLQEKSA
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atggtgcaagccaatccaccagccagcctgctcgacaagctgtgggccagccacgtgatt
cacgagcagtccgacggaccttcgctgatctatatcgaccggcacctggtcaatgaggta
accagcccacaggccttcgaggggctgcgcctgcatggccgtgaggtatggcgtcctgca
tcggtgctggccacggccgaccacaacgtgccaactaccgaacgggcggcgggcattgcc
gacccgatcagccgcgcgcaggtcgacgcactcgagcgcaactgcgctgcgactggaatc
gtgaacttcggcatgaacgacccgcgccagggcattctgcacgtggtgggtcccgagcgt
ggcgcgacgctgcccggtatgaccattgtctgcggcgactcacatacatccacacatggc
gccttcggagccttcgctttcggtatcggtacctcggaagtcgaacaggtgctcagcgcg
cagtgtctgtggatgaaaaagccgcgctcgatgctggtccgggtagaaggtgagttggcg
gcaggtgtttcagccaaggacatcgcgctggcgctgatcggacgcattggtacggcggga
gcgaccgggtacgtgatcgagttcgccggcagcaccatccgtggcctcagtatggaaggg
cgcatgaccgtctgcaacatggcgatcgaggcgggggctcgcgctggcatggtggccgtg
gacgaaaccacgttggcatacttggcccatcgcccgcaggcgccgcaaggtgaagcatgg
gaaagtgccagcgcctactggcgcacgctgcgcagcgatccggacgcagtgttcgacgcg
gtcgtggacattggtgttgcgacgatccggccgcatgtgacatggggcacgtccccggaa
atggtggtggcgatcgacgagcgcattcccgatccgcgacaggaagccgatccggtcagg
cgccgtggcatggaacgggcactaacctacatggggctggagcccggcatcaaagtggca
tctatcgcgctcgataaggttttcatcgggtcgtgcaccaatgcacggctcgaggacttg
cgagccgccgccgacgtgctgcgcggccgccacgtggcgtcgaacattcgtcaggcgcta
gtggtgcccggctccgggctggtgaagtcccaagcggaagcggaaggccttgacagggtt
ttcatcgacgctggcttcgagtggcgtgagcctggatgctcaatgtgcctgggcatgaat
gacgatcgtcttgctcctggtgagcgctgcgcatccacctcaaatcgcaacttcgaaggc
aggcaggggcccggtggtcgcacccacctggtcagcccgcaaatggccgcggcagcggcg
gttgccgggcactttgtcgacgtaagcaccgtgctgcaggagaagtcagcgtga
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