Rhodococcus opacus B4: ROP_53350
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Entry
ROP_53350 CDS
T00882
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
rop
Rhodococcus opacus B4
Pathway
rop00290
Valine, leucine and isoleucine biosynthesis
rop00660
C5-Branched dibasic acid metabolism
rop01100
Metabolic pathways
rop01110
Biosynthesis of secondary metabolites
rop01210
2-Oxocarboxylic acid metabolism
rop01230
Biosynthesis of amino acids
Module
rop_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rop00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ROP_53350 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ROP_53350 (leuC)
Enzymes [BR:
rop01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ROP_53350 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ROP_53350 (leuC)
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BAH53582
NITE:
ROP_53350
UniProt:
C1AV92
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All DBs
Position
complement(5814990..5816396)
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AA seq
468 aa
AA seq
DB search
MFMGKTLAEKVWDAHVVRRDEGEPDLLYIDMHLLHEVNTPQAFDGLRASGRTVRRPDLTL
GTEDHNTPTVAVDKEIVDPAAREQVSLMHKNCAEFGIELFRLGEEHQGIVHVIGPELGLS
HPGSTIVCCDSHTATQGAFGSLAFGIGTSQVEHVLATQTLPMGRLKNMAVTVNGSLPEGV
TAKDLILAIIARVGTAGGQGHIIEYRGQAIDELSMEGRMTVCNMSVEAGSRAGMIAPDEK
TFAYLRGRPAAPGADRWDAEVAYWRTLFTDEDAVFDKEVVIDASTLTPFVSWGTTPAQSA
PLGDPVPHPEAFADPVERAAVQRAQEYMDIVPGRPVRGLPVDVVFIGSCTNSRIEDLREV
ARVLDGRKVAPGVDLMIVPGSMKVRQQAIDEGLNEVFEAAGAGLRFAGCSMCAALNEDRL
TPGQRAASTNNRNFEGRQGKGSRTHIVSPAVAAATAVAGHLAAPADLT
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgttcatgggtaagacactggccgaaaaggtgtgggacgcacacgtggtgcgccgcgac
gagggcgagccggacctgctctacatcgacatgcacctgctgcacgaggtgaacaccccg
caggcgttcgacgggctccgggccagcggccgcacggtgcgccgacccgacctgacgctg
ggcaccgaggaccacaacacccccaccgtcgcagtggacaaggagatcgtcgatcccgcg
gcccgcgagcaggtgtcgctgatgcacaagaactgtgcggagttcgggatcgagttgttc
cggctcggcgaggaacatcagggcatcgtgcacgtcatcggaccggaactgggcctgtcc
catccgggttcgacgatcgtctgctgcgattcgcacaccgccacccagggcgccttcgga
tcgttggcgttcgggatcggcaccagccaggtcgagcacgtcctggccacccagacgctg
ccgatggggcggctgaagaacatggccgtcaccgtgaacggatcgctgcccgagggggtg
acggcgaaggacctgatcctggcgatcatcgcgcgggtcggcaccgccggcggacagggc
cacatcatcgaataccgcggccaggccatcgacgagctgtcgatggagggccggatgacg
gtgtgcaacatgtccgtcgaggccgggtcgcgggccgggatgatcgccccggacgagaag
accttcgcatatctgcggggccggcccgccgccccgggtgcagaccggtgggatgccgaa
gtagcgtactggcgcaccctgttcaccgacgaggacgccgtcttcgacaaggaggtcgtc
atcgacgcctccaccctcaccccgttcgtgtcctggggcaccacccccgcgcagagcgca
ccgctgggggacccggtcccccatccggaggcgttcgcggacccggtcgagcgggccgcc
gtgcagcgagcacaggagtacatggacatcgtccccggacgcccggttcgcgggctgccg
gtcgacgtcgtgttcatcggctcgtgcacgaacagccgcatcgaggacctgcgcgaggtc
gcgcgcgtcctcgacggccggaaggtcgcgcccggggtcgacctgatgatcgtgcccggg
tcgatgaaggtgcgtcagcaggcgatcgacgagggcctgaacgaggtgttcgaggccgcc
ggggcgggactgcggttcgccggctgctcgatgtgcgcggcgttgaacgaggatcggctc
acccccggccagcgcgccgcgtcgacgaacaaccgcaacttcgagggccggcagggcaag
ggctcgcgcacccacatcgtctcccccgccgtcgccgcggcgaccgccgtcgccggccac
ctcgccgcacccgccgacctgacctga
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