Rhodococcus oxybenzonivorans: CBI38_07855
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Entry
CBI38_07855 CDS
T08279
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
roz
Rhodococcus oxybenzonivorans
Pathway
roz00860
Porphyrin metabolism
roz01100
Metabolic pathways
roz01110
Biosynthesis of secondary metabolites
roz01120
Microbial metabolism in diverse environments
roz01240
Biosynthesis of cofactors
Module
roz_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
roz_M00925
Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
roz_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
roz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CBI38_07855
Enzymes [BR:
roz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CBI38_07855
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CBI38_07855
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AWK71518
UniProt:
A0A2S2BSH2
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Position
1655212..1656777
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AA seq
521 aa
AA seq
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MSRVRKNTPGRILFVGSGPGDPALLTVHARDVLAAATLAFTDPDVDKGVTVLVGTDLGVD
AETGEPLAEVRPALGEPAEVAKTLVHEARNGHDVVRLVSGDPLTTDSVIAEVAAVARTQV
QFEVLPGLPAASAVPSYAGMALGSGHTEADVRGEVDWAALAAAPGPLVLHATSGHLAETA
SALVEHGLAPQTPAAITVRGTTRQQRTVEATLATLNEAGSELVGSLVVTVGKVVAQRSKM
SWWESRALYGWKVLVPRTKDQAGEMSDRLVTHGAIPIEVPTIAVEPPRSPAQMERSVKGL
VDGRYQWVVFTSTNAVRAVWEKFEEFGLDARAFSGVKIACIGEATAAKVRSFGINPELVP
SGEQSSEGLLAEFAPYDDVFDPVNRVLLPRADIATETLAEGLRERGWEIDDVTAYRTVRA
APPPAETREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPKTAETAVEFGLR
VDVQPETAQVGPLVEALAEHAARLRAEGALPPPRKKSRARR
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagtccgaaagaacacccccggacggatcctgttcgtgggatccggaccgggc
gatccggccctgctcactgtgcacgcacgggacgtccttgccgcagcgacgctggccttc
accgaccccgacgtcgacaagggcgtcaccgtcctggtcggcaccgacctgggcgtcgac
gcggaaaccggtgagccgctcgccgaggtccgcccggctctcggtgaaccggccgaggtc
gcgaagaccctcgtgcacgaggcccgcaacggccacgacgtcgtccgcctcgtgtccggt
gacccgctgactaccgattcggtgatcgccgaggtcgcggcagtggcgcgcactcaggtg
cagttcgaggtcctgcccggactccctgccgcgtccgctgtgccgtcgtacgccggcatg
gcgctgggctcgggacacaccgaggccgacgtccgcggtgaggtcgactgggcggcgctg
gccgcggcgcccggaccgctggtgctgcacgccacgtcggggcacctggccgagacggcg
agcgcgctcgtcgaacacggtcttgctccgcagaccccggccgcgatcaccgttcgcggc
accacccggcagcagcgcacggtcgaggccaccctcgccaccctcaacgaggccggttcc
gaactggtcggctccctcgtggtgacggtcggcaaggtcgtggcccagcgcagcaagatg
tcgtggtgggaatcgcgtgccctgtacggctggaaggtcctcgtgccccgcacgaaggat
caggccggggagatgagcgaccgcctggtcacccacggcgccatcccgatcgaggtgccg
accatcgccgtggagccgccccgcagtcccgcccagatggaacgttccgtcaagggcctg
gtcgacggccgctaccagtgggtggtgttcacctccaccaacgcggtgcgtgcggtgtgg
gagaagttcgaggagttcgggctcgacgcccgcgcgttctccggtgtcaagatcgcctgc
atcggcgaggccacggccgccaaggtccggtcattcgggatcaaccccgaactcgtgccg
tccggtgagcagtcgagcgagggcctgctggccgagttcgctccgtacgacgacgtgttc
gaccccgtcaaccgggttctgttgccccgcgccgacattgccaccgaaacactcgccgag
ggtttgcgtgaacgcggctgggaaatcgacgatgtcaccgcctaccgcaccgtccgggcc
gcgccgccgccggccgagacccgcgagatgatcaagaccggtgggttcgacgcggtctgc
ttcacctcgtcgtcgacggtccgcaatctcgtcggtatcgcgggaaagccgcatgcacgg
accctcgtggcctgcatcggtcccaagaccgcggaaaccgcagtggagttcggacttcgc
gtggacgtacagccggagaccgctcaggtcggcccgctggtggaggctcttgccgagcac
gccgcgcgactgcgcgccgagggtgcactgcccccgccgcgcaagaagtcccgcgcccgg
cgatag
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