Saccharomonospora xinjiangensis: EYD13_07745
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Entry
EYD13_07745 CDS
T05928
Symbol
eryA1
Name
(GenBank) Erythronolide synthase, modules 1 and 2
Organism
sacc
Saccharomonospora xinjiangensis
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
AMP-binding
PP-binding
KAsynt_C_assoc
PKS_DH_N
adh_short
PS-DH
Epimerase
Thiolase_N
AMP-binding_C
GDP_Man_Dehyd
Polysacc_synt_2
ACP_syn_III
NmrA
NAD_binding_4
RmlD_sub_bind
Motif
Other DBs
NCBI-ProteinID:
QBQ59913
UniProt:
A0A4P7C5U5
LinkDB
All DBs
Position
1609512..1627439
Genome browser
AA seq
5975 aa
AA seq
DB search
MARSELIRPLSELLRAHAGRRGEKVAYSDARRSVTYAELEQRTARLAGHLADRGLSRGGR
VLIWFNNSVEMVEGYLTSVRAGGVGVPVHPRASDDELAYLIEDSGAEVVLTDAAHLEQLH
RVSGDANLVVVAAGQVKPATAGGVSSFEELATTEPASPARDDTGLDDLAWMLYTSGTTGR
PKGVLSTQGSCLWSVAACYVPLLGLSPEDRVLWPLPMSHSLAHILGVHGVIAAGASAHIT
DGFAGDEIARLMREESYTFLVGVPTMYHDLLRHARTEGLDADSLRVCMVTGAVTSASLSR
SFEDTFGVRLIDSYGSTETCGAITMNRPTGPLVAGSCGSPVPGLKVRIVEPGTGKEAEPG
VEGEVWVKGPTVMLGYHNQPEATAAALRDGWYRTGDLAVRDELGYLTITGRIKELIIRGG
ENIHPAEIEDVVSTVAGVADAAAVGRPDAELGEVPVVYVVAEVPGEVDAEAIVMACRRHL
SYYKVPSAVYEVEAIPRTASGKVARRKLLGTQAREHSTGSTVLAGLSRIDWTPIAGGPSR
RPEPGEWAILGADEFGFAADGIPVSAYADLAALGDAVEAGTPAPRTVLTDAPASVEHARA
LVESWLGDERFAATRLVVVTRFAVGTGSEAAVDPSGAPAWGVVRAAGDTDRLGLVDVGEA
MLAELITAVGAGKPEVAVRDGVLRVPRLAPVRVPSTPSEPAAGTAMVVGDEAGIVAAHLS
SRGFGAVVTVGEDEIADVLTQVPDEHPLHTVVYAVEGDPAERMAGARLLHEVTRDAAPAA
FVLLCPVESLLGRGTEPGEAAAGAFLSALTQQRRAEGLASLALGVPADQSTQDFAALLDI
TQATDEAVLLAVEDDALTEAPAPARSESSQPQAGALRERLTGLTRQEQDRLLLALVRTET
AGVLGYGNPARIPARRAFKELGFDSKTAVELRTRLASATGLDLPATVVFDRPSAAELAEH
LRAELLGLRTEATRVHERAESAAADDPIAIVGMACRLPGGVNTPAELWKLAADGVDALSG
FPVDRGWDLAGLFDDDPDRAGTSYVREGGFLHDVAGFDAGFFGISPREALAMDPQQRLLL
EVSWEALEHAGIDPQSLRETDTGVFAGMMFHDYGGDRTRAPEDLEGYLGTGNAGSVLSGR
VSYVLGLHGPSVTVDTACSSSLVALHLAAQSLRTGECSLALAGGVAVMATPSVFVEFSRQ
RGLAPDGRCKSFADAADGTGWSEGVSLLVVERLSDAVRHGHRVLAVVRGSAVNSDGASNG
LTAPNGPSQVRVIRKALESGGLRPSDVDVVEAHGTGTRLGDPIEAGALVEVFGSGRRGSP
LLLGSVKSNVGHTQAAAGVAGVIKMVESLRRGVVPGTLHVDAPSSRVDWSSGAVELVTSA
TEWPEVDRPRRAGVSSFGVSGTNAHVIIEQAPEQPEAPEPGAAPTIWTVSGRSEKAVRAQ
ASRLLSAVDTLNPVDVGYSLATTRAALDFRAFAAGDNRDDLHEQLRAIALGTTPVLPADV
EQGPVFVFPGQGSQWVGMVLGLLESSSVFAEAFGEVAGVVEGLVDWCVVEELGGGLDRVD
VVQPVLFVVLVSLARLWESCGVVPVGVVGHSQGEIAAACVAGGLSVEDAARVVVLRSRLI
AGVLAGRGGMVSVGLPVGEVVSRLPVGVGVAAVNGPSSVVVSGDVGGLEGFVSGCERDGV
RVRWVAVDYASHSEQVGLVRDELLSVLSSVVPRSSSVPFFSTVTGGWLDTAELGAEYWYR
NLRETVRFSDAIETLEAEGFKSFIEVSPHPVLTMSIEESVVDGAVVGTLRRDDGGFDRFL
RSLGEAHARGVEVDWSAVFDGSGARRVDLPTYAFQHERYWLESTPAAGDPAGLGVASAGH
PLLGAAVDLAGGDGLVLTGRLTTATQPWLADHSVHGTVIVPGSAFVELALRAGRELGHDR
IDELTLEAPLVLDDTDTIVQVVVAPDGRGVSIHSRHTGDQTWTRHAQGVLASGAEPVSGP
LAAFRNWPPAEAQPLAVEDFYERLAETGLAYGPSFQGLRAAWRHGNEVFAEIRLPEPVED
AGEFSVHPALLDAAVHGVDLGVLEPGERRLAFAFSGVTLHAVGARVLRVHLAPAGQDAVS
LTAADETGALVVSVDTLVLRHTASPPRRRVAARSMYTLDWTAPQSPAPEPTRWAVLDPGE
HSAGGWLTAPGRCAGSYADLDALAGAVAQGEPVPDVLVAAGTPGAANPAAAARELLAEVS
ATVRAWLADARFGDSRLVLLTSNAVATGSEGATPDLAQAPLWGLLRSAASEHPGRFALVD
LDGEDSSFLALPDALALPEPQVAIRSGRVLAPRLARADATAAPRWNAEGTVLITGATGGL
GRLVARHLATEHGVRHLLLLARSAPSAEVAAEFGDLDAEVTFAECDVADRAALADVLSGI
DDAHPLTGVVHTAGVVDDGIVEALTGEQFDRVLSPKLDGALALHELTKDMDLSAFVLFSS
AAGILGTPGQGNYAAANVFLDALAAHRRRSGLPGVSLAWGVWAESAGMGGRLAETDLARM
ARGGTVALSAAEALALLDAATGSDAPALVPMGLDTTVLAAQDDVPELFRGLVRAQPRRAA
RAEPEDGLPLARRLAPLPVEERERMLSELVHTHAAAVLGHGSGSDLDGGRSFKELGFDSL
TAVEFRNRLSNATGLRLPPTLIFNHPTPGALAAHLAEELLGTANESGEPAAPPATSASTE
DDPVVIVAMSCRFPGGVDSPERLWQVVADEVDTIGPMPEDRGWEPDRLYDPDPEQPGKTY
LVEGGFIEGLGRFDAEFFGINPREALAMDPQQRLLLETAWEVFERAGIDPRSLRGAQVGV
FTGTHGQDYGALLDGAPPDLEGYKATGTAGSVVSGRLSYTFGFEGPSMTVDTACSASLVA
LHQAANALRGGECSMALVGAASVMSTPEPFVMFSRQRVLARDGRCKSFAAAADGTGMSEG
VGMLLVERLSDARRLGHPVLAIVRGSAVNSDGASNGLTAPHGPSQERVIRQALADAGLTG
GDVDVVEAHGTGTALGDPIEAHALLATYGRDRSPEHPLWLGSVKSNLGHTQSAAGLAGVI
KMVLAMEHATLPKTLHVDAPTPHVDWELGGVRVLSDAREWPSNGHPRRAGVSSFGISGTN
AHVVLEQPPSEAPSASPATPAPLTSALPWVLSAKTEDALRAQAERLREHVENLAEVDVAS
IGLSLATSRTAHPHRAAVIGREIPEFTAGLDSIVHGTDAPNLVRALATPGKVAFVFPGQG
SQWPEMATDLLATSPVFADRLRDCDEALREFVDFSVLAVLRGEPGAPALDRLRVVQPVLF
SVMVALAELWRSRGVHPAAVVGHSQGEVAAACVAGALSLEDAARVVALRSRLIDEELSGK
GGVVSVALAADELAPRLARWGEKLSIAAVNSPTAVAVAGDPEALDELMAELEADQIRARR
IRGAHAAGHTAQIDRLRERLLEELAPVTPRADAVPFYSTVTGAAVDPSTLDAEYWYRNAR
EPVLFEKAVRALSAEGHTAFVESSPHPVLLGAIQETVEDAAVIGTLRRDDGGQDRVVTSL
AEAHVRGVVVDWAAVFPSGARKVSLPTYAFQRKHFWLDRSTAASDVTSAGLDPAGHPLLG
AAVPVPQFGGFLCTGRLSAHAQPWLTEHPSGVNIVAPAVFVELALRAGEEFGCDRLADLT
VEAPLALPEQGGVRVQVTVGGPDDEGRRAVAVYAQPDTDAGREWTLHASATLTAREGTQP
APLAVWPPEGATELGHDAATGVRRAWQRDGDLFAEIVVPEESATGEFGLHPMLLETAVHC
AGPLRGRPAGTVAARWRDVTLHATGARALRVHLSEREPDALSLAAFDETGSPVLSATVET
RPVDGFRAALGHGDALFRLLWTELSLPDTEPGNGMVLGEDHADPAELASAIAGGAPVPDY
VVVPADPGTGSTENTENTENTENTAEAAGACALRVLTLLRKWLAEERLAPVTLVVLTTGA
VATGADEDVPGLAQSSIWGLVRSAQTENPGRVVLVDVDTHEAPAHLLPAVVASGEPQAAI
RAGTVLVPRLARTRPAEQPVAPAFDAEGTVLITGGTGALGALLAEHLVTAHGVRHLLLTS
RTGNRSSSAARLCDRLGALGATVTVESCDVADRAALESLLSRIPSAHPLTAVVHAAGVID
DGVLDSITPERLDAVLRPKVAGALNLHELTEGLPLSAFVLFSSGAGIFGSPGQANYAAAN
TVLDALAHHRQHRGLPARSLAWGLWAERGDQSSGLGETDLARLARTGTVEIPAEHGLALF
DAARTACDALVVPTRLDFAALRAQARAGSLPHLLRGLVRVAAKTASAEPEGSSLAARLST
SSPAERRETVLQLVRSTAAAVLGHTGLDTIGARRAFREVGFDSLTAVEFRNRLQAGAGLR
LPATLVFDHPTPQAVTDHLLSELFGDPGSDAGPRAVATERADSATEPIAIVAMSCRFPGG
VRSPEELWRLLEAGGDAITELPSDRGWDLESLYHPDADQPGTSYVREGGFLHDAAEFDAG
FFGISPREAVAMDPQQRLLLETCWEVLERAGIDPTSLRGSRTGIFTGTTGQDYAALAEHL
PQSDEGFLVTSTGASVLSGRVSYTLGLVGPAMTVDTACSSSLVALHLAAQALRSGECTLA
LAGGATVLATPRTLVAASRQRGLSPDGRCKAFSDDADGFGMAEGAGILLLEKLSDARRNG
HPVLAVLSGSSVNQDGASNGLTAPNGPSQQRVIREALDAAGLTAAEVDVVEAHGTGTSLG
DPIEAQAVLATYGREHGNDNPLWLGSVKSNIGHTLGAAGVAGVMKMVLAIQHGVIPKTLH
AETPSTHVDWTEGAVALAREAVPWPDTGRPRRAGVSSFGISGTNAHAIVEQAPDTEVTEP
ERTLSLRRVPVVVSARSAAALAGQARRLGDWLAERSDLTDLTDLTDLAFSTVTSRAALEH
RAVITAESRDELMRALRALADGGVASNLVRGEQRDEVTCAFVFSGQGSQRPGMGRELHET
YPVFARAFDEVCAKLDARLDGYADHPVREVVFAETPDGAELLDQTVYTQAGLFAFEVALF
RLLTHWGVRPGYVLGHSIGEVAAAHVAGVLYLDDAATLVAARGRLMQALPSGGAMVAVEA
SEEDVLPLLDGAGTVGIAAVNGPKATVLSGEEDAVLAVAAALASRGAKTKRLRVSHAFHS
PLMHGMLDEFTTIAEKLTYHAPVIPLVSNLTGQLATDEIRSAGYWARHVAEAVRFGDSVR
RLAGQGTDVFVELGPDGVASAMAADSAGEQALTVATCRKDRPEPVTLIGALARLHANGVS
PDWAAFFSGTGATRTELPTYAFQRRRYWLDAPSRPAEAEQSWRYRMDWQPIPTTAAPVLP
GHWLLVLPDGAIDDATDDAWRATLLEGSGAQVSTVHLDPAGDRGTAAERIRAAVGDSAIT
GVLSLLGLDDRAHPAHPSASLGLSATVLLLQALGDAAIDSPLWCATQGAVATEPGEAVTS
LTQAQLWGLGRVAALEYPGRWGGLIDLPPSPETARHHVIAVLADARGEDQLAVREAGVLA
RRLVRAEPVEGGTEWVPSGTVLITGGTGALGGHVARRLAAEGAEHLLLVSRRGPDAPGAA
ALAEELTGLGARVSVVACDIADRDGVAALLADIPDQHPLTAVVHTAGVVSDGVLDTMTPE
KIAEVMRPKADAALHLHELTRHLDLSAFVLYAAMAGAVGSPGQGNYAAANAFLDALAERR
RAEGLPALSVSWGWWEGDGMAKLDGVDQSRLRRNGLLPMAPERAVAELFDALRTDDATLL
VTNVDWPRFVPAFTTTRSSALLEPVTVRVAAPTATQAVTVADEPDAVSDLLGRLAGADAT
ERARLMLDLVCSHVAEVLGYDSSDTVEVSRGFLELGFDSLTAVELRNQLTARTGLRLPPT
LIFDYPSPSALADWLTTQVLGGSGNGGDPREAEVRGLLASIPLTRLDEAGLLDDLLRLGR
GAENTDEGQANGEAEQLDDLDVADLVRLAREDLDR
NT seq
17928 nt
NT seq
+upstream
nt +downstream
nt
atggcgcgatccgagctgatccggccgttgtccgagttgctgcgagcacacgccggacgg
cgcggtgagaaggtcgcgtattcggacgcgcggcggtcggtcacctacgcggaactggag
cagcggaccgcccggctggcaggccacctcgccgatcgggggttgtcccgtggcgggcgc
gtgctgatctggttcaacaacagcgtcgagatggtcgagggctacctcacctcggtgcga
gcaggcggcgtcggcgtgccggttcaccctcgcgcctccgacgacgaactcgcctacctg
atcgaggacagcggcgccgaggtggttctcaccgacgcggcgcacctggaacagctgcac
cgggtcagcggtgacgcgaacctcgtggtggtcgccgcggggcaggtgaagccggccacc
gcgggcggcgtgtcgtcgttcgaggagctggccaccaccgaaccggcgagcccggcccgt
gacgacaccgggctcgacgacctcgcctggatgctctacacctcgggcaccacgggcagg
cccaagggagtgctctccacccagggcagctgcctgtggtcggtcgccgcctgctacgtg
cccctgctgggattgtctcccgaggaccgggtgctgtggccgctgccgatgtcgcactcg
ctggcgcacatcctcggcgtccacggtgtcatcgccgcgggcgcgagcgcccacatcacc
gacggcttcgcgggcgacgagatcgccaggctgatgcgggaggagtcctacaccttcctc
gtcggcgtgcccacgatgtaccacgacctgctgcggcacgcgcggaccgaggggctggac
gccgactcgctacgggtgtgcatggtcaccggtgccgtcacctccgcctcactcagccgg
tccttcgaggacaccttcggcgtccggctgatcgacagctacggcagcaccgaaacctgt
ggcgcgatcacgatgaaccgccccacggggccgctggtcgccggttcctgcgggtcgccg
gtacccgggctgaaggtgcggatcgtggagcccggcacgggcaaggaggccgagcccggc
gtcgagggcgaggtgtgggtcaagggccccaccgtgatgctcggctaccacaaccagccg
gaggccaccgccgccgcgctgcgggacggctggtaccgcacgggggatctcgccgtcagg
gacgagctggggtatctgaccatcacgggccggatcaaggaactgatcatccgtggtggg
gagaacatccatcccgccgagatcgaggacgtcgtgagcacggtcgccggtgtcgccgac
gcggccgccgtgggcaggccggacgccgaactcggcgaggtgcccgtggtgtacgtggtc
gccgaggtcccaggtgaggtggacgccgaggcgatcgtcatggcgtgccgcaggcacctg
tcctactacaaggtgccttctgcggtgtacgaggtggaggccatcccgcgcacggcgtcg
gggaaggtggcccgccgcaagctgctcggcacgcaggccagggaacacagcacgggcagc
acggtgctcgccgggctgtcccggatcgactggacaccgatcgcgggcgggccgtcccgt
cgtcccgagccgggggagtgggcaatcctcggtgcggacgagttcggcttcgcggccgac
ggcatcccggtctcggcgtatgccgatctggcggcgctcggtgacgctgtcgaagcggga
acgcctgcgccgcgaacggtactgaccgacgccccggcatcggtggagcacgcccgtgcg
ctggtggagtcgtggctgggcgacgagcggttcgccgccacgcgactggtcgtggtgacc
aggttcgcggtgggcaccggctccgaggccgccgtcgatccgtccggcgcgcccgcctgg
ggtgtggtcagggcggccggtgacaccgaccggctcgggctggtggacgtgggtgaggcc
atgctcgccgagctgatcacggccgtgggtgccgggaaacccgaggtagccgtgcgcgac
ggggtgctgcgagtcccgaggctcgcaccggtccgggtgccgtccacgccaagcgaaccc
gctgccggcacggcgatggtcgtcggcgacgaggccgggatcgtggcagcgcacctctcc
tctcgtgggttcggcgctgtcgtcacggtgggcgaggacgagatcgccgacgtgctcacg
caggtgcccgacgagcatcctctgcacaccgtggtgtacgccgtcgagggtgacccggca
gagcggatggccggtgcgcgcctgctgcacgaggtgacccgtgacgccgcacccgcggcg
ttcgtgctgctctgcccggtggagtcgctcctcggacgcggcaccgaacccggcgaagcc
gccgcaggtgccttcctgtcggccctcacccagcagcgcagagcggagggactggcctcc
ctcgcactcggcgtcccggccgatcagtccacacaggacttcgccgcactgctcgacatc
acgcaggccaccgacgaagccgtgctgctcgcggtggaggacgacgcgctcaccgaagcc
cccgccccggcgaggagcgagagctcacagccgcaggcaggcgccctgcgggaacggctc
acgggcctgacccgccaggaacaggaccgcctcctgctcgcgctggtacgcaccgagacc
gccggtgtgctcggctacggaaaccccgctcgcatacccgcccggcgtgccttcaaggaa
ctgggcttcgactccaagacggcggtcgagttgcggacccggctcgcctcggccacggga
ctcgacctgcccgccacggtggtgttcgaccggccgagtgcggccgagctggccgagcac
ctgcgtgccgaactcctcggactgcgaaccgaagccacccgggtccacgagcgcgccgag
agcgccgccgccgacgaccccatcgcgatcgtcggtatggcctgccgtcttcccggcggc
gtgaacacgcccgccgaactgtggaagctcgccgccgacggtgtcgatgcgttgtcgggt
tttccggtggatcggggttgggatcttgcggggttgttcgatgacgatccggatcgggct
gggacgtcgtatgtgcgtgagggtgggttccttcacgatgtggcggggttcgatgcgggg
ttcttcgggatctctccgcgtgaggcgctggcgatggatccgcagcagcggttgttgctt
gaggtgtcgtgggaggcgctggaacacgcgggcatcgacccgcagtcgctgagggaaacc
gacaccggtgtcttcgccgggatgatgttccacgactacggcggcgaccgcaccagggca
ccggaggacctcgaaggctatctcggcacaggcaacgcgggcagtgtgctgtcgggccgg
gtgtcctacgtcctcggccttcacggcccttcggtgaccgtggacacggcctgctcctcc
tcgctcgtcgcgctgcacctcgccgcccagtcgctgcgtaccggcgaatgctcgctggcg
ctggccggtggtgtggccgtgatggcgacaccgtcggtgttcgtcgagttcagcaggcag
cgcggtctggctccggacgggcgctgcaaatcgttcgccgacgccgccgacggcaccggc
tggagcgagggcgtgagcctgctcgtggtggagcggctctccgacgccgtgcggcacggc
caccgcgtactggccgtcgtgcgtggctccgccgtcaactccgacggagccagcaacggg
ctgaccgcgccgaacgggccgtcccaggtccgtgtcatccggaaagcactcgaaagcggt
ggtttgcgaccgtctgatgtggatgttgtggaggcgcatgggacggggactcggttgggg
gatccgatcgaggctggcgcgttggtggaggtgttcggctctgggcggcggggttctccg
ttgttgttggggtcggtgaagtcgaatgttggtcatacgcaggctgcggctggtgtggct
ggtgtgatcaagatggtggagtcgttgcggcgtggtgttgtgccggggactttgcatgtt
gatgcgccgtcgtcgcgggtggattggtcctcgggtgcggtggagttggtgacgtccgcg
accgagtggccagaagtggatcgtcctcgcagggctggggtgtcgtcgttcggggtcagc
ggaaccaacgcccacgtcatcatcgaacaagcaccggagcagcccgaagcacccgaaccc
ggcgcggcccccaccatctggacggtgtcggggcgcagcgaaaaggccgtccgcgcgcag
gcgagccgcctgctctccgctgtggacacactcaaccccgttgacgtcggctactcactg
gcgaccaccagggccgcactcgacttccgcgctttcgccgccggtgacaaccgcgacgat
ctgcacgaacaactgcgcgccatcgcactcggaacaacccccgtccttcccgccgacgtc
gaacagggccccgtttttgtttttccggggcagggttcgcagtgggtggggatggtgttg
gggttgttggagtcgtcttcggtttttgcggaggcgtttggtgaggttgcgggtgtggtg
gaggggttggttgattggtgtgttgttgaggagttggggggtgggttggatcgggttgat
gtggttcagcctgtgttgtttgtggtgttggtgtcgttggctcggttgtgggagtcgtgt
ggggttgttcctgtgggtgtggtggggcattcgcagggtgagattgcggcggcgtgtgtt
gcgggtgggttgtcggtggaggatgcggcgcgggttgtggtgttgcgttctcggttgatt
gcgggggtgttggctggtcggggtgggatggtgtcggtgggtttgccggtgggggaggtg
gtgtcgcggcttccggtgggggtgggggttgcggcggtgaatggtccttcttcggtggtg
gtgtcgggtgatgtggggggtttggaggggtttgtttctgggtgtgagcgtgatggtgtt
cgggtgcggtgggtggcggtggattatgcgtcgcattcggagcaggtggggttggttcgg
gatgagttgttgagtgttttgtcgtcggtggtgcctcggtcgtcgtcggttccgtttttt
tcgacggtgacgggtgggtggttggatacggcggagttgggtgcggagtattggtatcgg
aatttgcgggagacggtccggttctccgacgcgatcgagacgcttgaggctgagggtttc
aagtctttcatcgaggtcagtccgcatccggtgctgacgatgagtatcgaagagtccgtc
gtggacggtgctgtggtcggcacgttgcggcgtgacgacggcgggtttgaccggttcctg
cgctccctcggcgaggcccacgcccggggtgtcgaggtcgattggtccgccgtgttcgac
gggagtggcgcgaggcgcgtcgatctgcccacctatgccttccagcacgaacgctactgg
ctcgaatccactccggccgccggagacccggcaggcctcggggtggcctcggccgggcac
ccgctgctcggcgcggcagtcgatctcgcaggcggtgacggccttgtgctgaccggacgc
ctcaccaccgcgacacagccgtggctcgccgatcactccgtgcacggcacggtgatcgta
cccggttcggcgttcgtggaactcgcgctgcgcgccggccgcgaactcggccacgaccgc
atcgacgaactcaccctcgaagcccccctcgtgctcgacgacacggacacgatcgtgcag
gtcgtcgtcgctcccgatggccgaggagtgagcatccactcccgtcacaccggcgatcag
acctggacccggcacgcccagggtgtgctggcctccggagctgagccggtgtccggtccc
ctcgccgccttccggaactggcctcccgctgaggcgcagccgcttgcggtggaggacttc
tacgagcggcttgccgaaaccgggctggcctacggtccctccttccaggggctgcgcgcc
gcctggcggcacggcaacgaggtgttcgccgagatccgccttcccgaaccggtggaggac
gcgggcgagttctccgtgcatcccgccctgctcgacgccgccgtgcacggcgtggacctc
ggtgtgctcgaaccgggcgagcggcgtctggccttcgccttcagcggcgtgaccctgcac
gcggtgggtgcccgtgtgctgcgggtgcacctcgctccggcaggtcaggacgcggtgtcg
ctgacagccgccgacgagaccggcgcgctcgtggtgtccgtggacaccctggtgctgcgg
cacaccgcgagcccaccacgcaggcgtgtggccgcgcggtcgatgtacacgctcgactgg
acggccccacagtccccggcgccggagcccacccggtgggccgtgctcgaccccggcgag
cacagcgcaggcggctggctcaccgcgccgggccggtgtgcgggcagctatgccgatctc
gacgcactggccggtgcggtcgcgcagggcgagccggtgcccgatgtgctcgtcgccgca
ggcacgccgggtgcggccaaccccgctgcggcggcacgggaactgctcgccgaggtctcc
gcgacggtcagggcatggctcgccgatgcgcggttcggcgattcccggctcgtgctgctc
acctccaacgccgtggcgaccggctccgaaggggccacccccgatctggcgcaggcgccg
ctgtggggactgctccgctcggcggcctcggagcaccccggccggttcgccctcgtggac
ctcgacggcgaggacagctccttcctcgcgcttcccgacgccctcgcgctgcccgaaccg
caggtcgcgatccggtcgggccgagtactggcgcccaggctcgccagagcggacgccacg
gccgcgccgcgctggaacgccgagggcaccgtgctgatcaccggagccacgggcggcctc
ggccgcctggtcgcgcgacacctggcgaccgaacacggtgtgcggcacctgctgcttctc
gccaggagcgccccgagtgccgaggtggcggccgagttcggcgatctcgacgcggaggtg
acgttcgccgaatgcgacgtggccgaccgcgcggcgctcgccgatgtgctctccggcatc
gatgacgcgcatccgctcaccggtgtggtccacaccgcgggtgtcgtggacgacggcatc
gtcgaagcgctcaccggcgagcagttcgaccgcgtgctctcgcccaaattggacggtgcg
ctcgctctgcacgaactgaccaaggacatggacctgtcggcgttcgtcctcttctcctcg
gctgcgggcatcctcggcacgccaggacagggcaactacgccgccgcgaacgtcttcctc
gacgcactcgccgcgcatcgccgccgcagcggcctgcccggtgtgtccctggcctgggga
gtgtgggccgaatccgccgggatgggcgggcgactcgccgagaccgacctcgccaggatg
gcgcggggtggcacggtggcactgagcgccgccgaggcgctggccctgctggacgccgcg
accggatcggacgccccggcgctggtgcccatgggactggacacgacggtgctggccgcg
caggacgacgtgccggagttgttccggggcctcgtgcgcgcacagccgcgccgtgcggcg
cgagccgaacccgaggacggtctcccgctggcgaggcggctcgcgccgctgccagtggag
gagcgggaacggatgctgagcgagctggtccacacccacgccgccgccgtgctcggccac
ggctcgggcagcgacctcgacggagggcgcagcttcaaggagctgggtttcgactcgctg
accgccgtcgagttccgcaaccggctctccaacgccaccggactccgcctgccaccgacc
ctgatcttcaaccacccgacccccggcgcgctcgccgcccacctcgccgaggaactgctc
ggcaccgcgaacgagtccggcgaacccgccgcgccacctgccacgtccgcgtccaccgag
gacgacccggtggtgatcgtggcgatgagctgccgcttccccggcggggtcgattcgccg
gaacggctgtggcaggtggtggccgacgaggtggacacgatcggccccatgccggaggac
cggggctgggaaccggaccggctctacgatcccgaccccgaacagcccggcaagacctac
ctggtcgagggtggcttcatcgaagggctcggccggttcgacgcggagttcttcggcatc
aacccgcgcgaggccctcgcgatggacccgcagcagcggttgctgctggagacggcgtgg
gaggtcttcgaacgcgcgggcatcgaccctcggtcgctgcgaggcgcgcaggtcggtgtc
ttcaccggaacccacggccaggactacggcgccctgctcgacggcgccccgccggatctg
gagggctacaaagccacgggtacggcgggcagcgtggtgtcgggacgcctgtcgtacacc
ttcgggttcgaggggccctcgatgaccgtggacacggcgtgctcggcctcgctggtggcg
ctgcaccaggccgcgaacgcgctgcgcggcggtgaatgctcgatggcgctggtgggcgct
gcgtcggtgatgtcaacacccgagccgttcgtcatgttcagcaggcagcgggtgctcgcg
agggacgggcggtgcaagtcgttcgccgccgccgccgacggcaccggcatgtccgagggc
gtcggcatgctgctggtggagcggctctccgacgcgcgccgcctcggccatcccgtgctg
gcgatcgtgcggggttccgccgtgaactccgacggcgcgagcaacggcctcacggcaccg
cacggtccctcgcaggaacgcgtcatccggcaggcgctcgccgacgcggggctcacgggc
ggggacgtggacgtggtcgaggcacacggaaccggcaccgcgctcggcgaccccatcgag
gcgcacgcgctgctggccacctacggtcgcgaccgctcgcccgaacacccgctgtggctc
ggctcggtgaagtcgaacctcggccacacgcagtccgcggccgggctcgccggtgtgatc
aagatggtgctggcgatggagcacgccacgctgccgaagacgctgcacgtggacgcgccg
acaccgcatgttgactgggagctcggcggggtccgcgtcctgtccgacgcccgcgagtgg
ccgagcaacggccatccccgccgcgccggggtctcctcgttcggcatcagcggtaccaac
gcgcacgtcgtgctcgaacaaccgccttccgaggcgccttcggcctcgcccgcgaccccg
gcgccactgacctcggcgctgccgtgggtgctgtcggccaagaccgaggacgcgctgcgg
gcgcaggccgagcgcctgcgcgagcacgtggagaacctggccgaggtggatgtggcctcg
atcggcctctccctcgccacgagccgcaccgcgcacccgcatcgcgccgccgtgatcggc
cgcgagatcccggagttcacggccgggctcgactccatcgtgcacggcaccgacgcgccg
aatctggtgcgcgccctcgccacaccgggcaaggtggccttcgtcttccccggccaggga
tcgcagtggcctgagatggccaccgacctgctggccacctcgccggtgttcgccgaccgg
ctccgtgactgcgacgaggcgctgcgggagttcgtggacttctccgtgctggccgtgttg
cgcggtgagcccggcgcccccgccctcgaccgcctccgcgtcgtgcagccggtgttgttc
tcggtgatggtggcgctggccgagctctggcgctcgcgcggtgtccaccccgccgcggtc
gtcgggcattcccagggtgaggtcgccgcggcctgcgtcgcgggcgcactgtcccttgag
gacgcggcgagggtggtggctctgcgctcgcgcctgatcgacgaggaactgtcgggcaag
ggtggtgtcgtgtcggtggcactcgcggcggacgagctggcaccacggctcgcacgctgg
ggtgagaagctctcaatcgcggcggtcaacagccccaccgcggtcgccgtcgcgggagac
cccgaggcgctcgacgagctgatggccgagctggaggccgaccagatccgcgcccgccgc
atccggggcgcgcacgcggcgggacacaccgcgcagatcgaccggctgcgcgagcggctg
ctggaggaactggccccggtcacgccgagggccgacgccgtcccgttctactcgacggtc
accggcgctgccgtcgatccgtccacgttggacgccgagtactggtaccgcaacgcccgc
gagccggtgttgttcgagaaggccgtccgcgcgctctccgccgaggggcacacggccttc
gtcgagtcgagcccccatccggtgctcctcggtgccattcaggagaccgtcgaggacgcc
gcggtgatcggcacgctgcgccgcgacgacggcgggcaggacagggtcgtcacctcgctg
gccgaggcgcacgtccgcggcgtggtcgtggactgggcggcggtgttcccctccggcgcg
aggaaggtgagccttcccacctacgccttccagcgaaagcacttctggctcgaccgctcc
acggcggcctccgacgtcacctccgctgggctggacccggcagggcacccgctgctcggc
gcggcggtgccggtgccgcagttcggcgggttcctctgcacaggacggctctccgcacac
gcccagccgtggctgaccgagcacccgtccggcgtgaacatcgtcgccccggccgtcttc
gtggaactcgcactgagggcgggcgaggagttcggttgtgaccggctcgccgacctgacg
gtcgaggccccgctcgcactgcccgaacagggcggggtccgggtgcaggtcaccgtgggc
ggccccgacgacgaagggcggcgcgccgtcgccgtgtacgcgcaacccgacaccgacgcg
ggccgggagtggaccctgcacgcctcggcgacgctgaccgctcgcgagggcacgcagccc
gcaccgctggccgtctggccgcccgagggtgccaccgaactgggccacgacgccgccacc
ggcgtgcggcgtgcctggcagcgcgacggtgacctgttcgccgagatcgtggtgcccgag
gagtccgcgaccggcgagttcggcctccatccgatgctgctggagaccgccgtgcactgt
gcgggcccgctgcgagggcgaccggcaggtacggtggccgcgcgctggcgggacgtcacg
ctgcacgccacgggcgctcgtgcgctccgggtccacctcagcgagcgtgaaccggacgcg
ctgagcctggccgcgttcgacgagaccgggtccccggtgctgtccgccaccgtggagacc
cggccggtggacgggttccgggccgctctcggccacggtgacgccctcttccgtcttctg
tggacggagctgtcgctgccggacaccgagccgggcaacgggatggtgctcggcgaggac
cacgccgatccggccgagctggcctcggcgatcgcaggcggcgcaccggtgccggactat
gtcgtcgtccccgccgaccccggtaccggcagtaccgagaacaccgagaacaccgagaac
accgagaacaccgccgaggcggccggtgcctgcgccctgcgtgtgctgacactgctgcga
aagtggctcgccgaggagcggctggccccggtaacgctcgtggtgctgaccacgggcgct
gtcgccaccggggctgacgaggacgtgccagggctggcgcagtcgtcgatctgggggctc
gtgcgctcggcgcagaccgagaaccccggcagggtcgtgctcgtcgatgtggacacccac
gaggcgcccgcccacctgctgcccgcggtggtcgcctccggtgaaccgcaggcggcgatc
cgtgcgggcacggtcctcgtgccgaggctggcgcggacccggcccgccgagcaaccggtc
gcgcccgcgttcgacgcggagggcacggtcctcatcaccgggggaaccggtgcactcggg
gcgctgctggccgagcatctcgtgaccgcgcacggtgtccgccacctgctgctgaccagc
cgcaccggcaaccggtcctccagcgcggcgcgactgtgcgacaggctcggcgcgctcggg
gccacggtgaccgtcgagtcctgcgacgtcgccgaccgcgccgcgctggagagcctgctc
tcccgtatcccctcggcgcatccgctcaccgccgtcgtccacgcggccggagtgatcgac
gacggcgtcctcgactcgatcacccccgaacggctcgacgccgtgctgcggccgaaggtc
gccggggcgctgaacctgcacgaactgaccgaggggctgccgctgtcggcgttcgtcctc
ttctcgtcgggagcggggatcttcggctcgccggggcaggccaactacgccgccgccaac
accgtcctcgacgcgctcgcccaccaccggcagcatcggggactgcccgcgcggtcgctg
gcctggggcctgtgggccgaacgcggtgaccagtccagcgggctcggcgagacggatctg
gcccgcctcgcccgcaccggaacggtggagatcccggccgagcacggcctcgccctcttc
gacgcggcacgcaccgcctgcgacgcactcgtggtgccgaccaggctggacttcgcggcg
ctgcgggcacaggctcgcgccggttccctgccccacctgctgcggggactggtccgcgtc
gccgcgaagacggcctccgccgaaccggagggttcgtcgctcgccgcgcgtctttccacc
tcgtccccggccgagcgcagggagaccgtgctccaactcgtgcgctccacggccgcggcg
gtgctcgggcacaccggtctcgacacgatcggtgcgcgccgcgccttccgtgaggtcggc
ttcgactcgctcaccgccgtcgagttccgcaaccggctccaggcgggtgcgggcctgcga
ctgcccgcgacgctggtgttcgaccacccgaccccgcaggcggtgaccgaccatctgctg
tcggaactgttcggcgaccccggctccgatgccgggccgagggcggtcgccaccgaacgc
gcggactcggcgaccgagccgatcgcgatcgtggcgatgagctgccggttccccggaggc
gtccggtcgccggaggagctgtggcgattgctcgaagccggtggcgacgcgatcaccgag
ttgccgtccgatcgtggctgggacctggaaagcctgtaccaccccgatgccgaccagccg
ggaacgagctacgtccgtgagggcgggttcctgcacgacgccgccgagttcgacgccggg
ttcttcgggatcagcccccgcgaggcggtggcgatggacccgcagcagcggctgttgctg
gagacctgctgggaggtgctggagcgcgcgggcatcgacccgacctcgctgcgcggcagc
cggaccgggatcttcaccgggacgaccggccaggactacgcggcgctggcggagcatctg
ccgcagtcggacgagggtttcctcgtgaccagcaccggcgcgagcgtgctgtcgggtcgc
gtgtcctacacgctcgggctcgtcgggcccgccatgacggtggacacggcgtgctcgtcc
tccctggtggcactgcacctcgccgcgcaggcgctgcggtcgggcgagtgcacgctcgcg
ctggccggtggtgccaccgtgctggccaccccgcgcacgctcgtcgcggcgagcaggcag
cggggactgtcgcccgacggccgctgcaaggcgttctccgacgacgccgatggcttcggc
atggccgagggcgctggcatcctgctgctggagaagctgtccgacgcgcggcgcaacggg
catccggttctggcggtgctgagcgggtcctcggtgaaccaggacggcgccagcaacggg
ctcacggcgccgaacggcccttcccagcagcgggtgatcagggaggctctcgacgcggcc
ggactgaccgcggccgaggtcgatgtcgtcgaggcacacggcaccggcacctcgctcggt
gacccgatcgaagcgcaggccgtcctcgccacgtacggcagggaacacgggaacgacaac
ccgctgtggctgggttcggtgaagtcgaacatcgggcacacgctcggcgcggccggtgtg
gccggggtgatgaagatggtgctggccatccagcacggggtgatcccgaagacgctgcac
gccgagacgccgtcaacccacgtcgattggaccgagggagcggtggcactggccagggag
gccgtgccgtggccggacacgggccgtccccgccgcgccggggtctcctcgttcggcatc
agcggcacgaacgcgcatgcgatcgtggaacaggcaccggacaccgaggtgaccgagccc
gagcggactctttctctgaggcgggtgcccgtggtggtgtcggccaggagcgcggcggca
ctggctggccaggcgaggcggctcggcgactggctcgccgagcgcagtgacctcaccgac
ctcaccgacctcaccgacctggccttctcgacggtgacctcaagggccgctctcgaacac
cgcgcggtgatcaccgctgagagccgtgacgagctgatgcgcgcgctccgggcactggcc
gacggcggggtggcctcgaacctggtgcgcggcgaacagcgcgacgaggtcacgtgcgcg
ttcgtcttctcaggccaggggtcgcaacgccccggcatgggacgcgaactgcacgagacg
tacccggtcttcgcgcgggcgttcgacgaggtgtgcgcgaagctcgacgcccggctggac
gggtacgcagaccacccggtgcgcgaggtggtgttcgctgaaaccccggacggtgcggag
ctgctcgaccagaccgtctacacccaggcgggactcttcgccttcgaggtggcgctgttc
cggctgctgacccactggggagtgcgccccggctacgtgctcggccactccatcggcgaa
gtggccgcggcacacgtcgccggtgtgctgtatctcgacgacgccgcgacgctggtcgcc
gcacggggacggctgatgcaggcccttccctccggtggggcgatggtcgcggtcgaagcg
tccgaagaggacgttctcccgctgctggacggcgcgggaacggtcggcatcgcggcggtc
aacggaccgaaggcgaccgtgctctccggcgaggaggacgccgtgctcgccgtcgccgcc
gccctcgcgtcccgaggagcgaagaccaagcggctacgggtcagtcacgcgttccactcc
ccgctcatgcacggcatgctcgacgagttcaccacgatcgccgagaagctgacctaccac
gcaccggtcattccgctggtgtccaacctgacaggacagctcgccaccgacgagatccgc
tcggcgggctattgggcccggcacgtcgccgaggccgtgcgtttcggcgacagcgtgcgc
cgcctcgccggtcagggcaccgatgtgttcgtcgaactcggacctgacggtgtggccagc
gccatggccgccgacagcgcgggtgagcaggcgctgacggtcgccacgtgccgcaaggac
cggccggaaccggtgacgctgatcggcgcgctggccaggctgcacgccaacggcgtgagc
ccggactgggcggcgttcttctccggtacaggcgccaccaggacagaactgccgacctac
gccttccagcgccgtcgctactggctggacgcacccagcaggcccgccgaggcggagcag
tcctggcgctaccgcatggactggcagccgatccccacgactgctgcgccggtgctgccg
ggccactggctgctggtgctgcccgacggcgccatcgacgacgccaccgacgacgcctgg
agggccaccctgctcgaaggcagcggcgcccaggtgagcaccgtccacctcgaccccgcc
ggtgatcgcggcaccgcggccgagcgcatccgcgcggcggtgggcgactcggcgatcacc
ggggtgctctccctgctgggactcgacgaccgagcgcacccggcccatccctccgcctcg
ctcggcctctcggccaccgtgctcctgctccaggcgctcggcgatgccgccatcgactca
ccactgtggtgtgccacgcagggcgccgtcgccaccgagccgggcgaggccgtcaccagc
ctgacgcaggcgcagctgtggggactcggccgcgtggccgccctcgaataccccggacgc
tggggtggactgatcgacctgccgccgtcgcccgagaccgcccggcaccacgtgatcgcg
gtactggccgacgcgcgaggcgaggaccagctcgccgtccgcgaggcaggcgtgctcgcg
cggcggctggtcagggcggaaccggtggaaggcggaaccgagtgggtcccttccggcacg
gtgctgatcaccggaggcaccggggcgctgggtggtcacgtcgcacggcggctggccgcc
gagggagccgagcacctgctgctggtcagccgcaggggaccggacgcccccggcgccgcc
gcgctggccgaggaactgaccggcctcggtgcccgcgtgtccgtcgtcgcctgcgacatc
gccgaccgcgacggcgtcgccgcgctgctggcggacatccctgaccagcacccgctgacc
gccgtcgtgcacacggcgggtgtggtgtccgacggcgtcctcgacacgatgacaccggag
aagatcgcggaggtcatgcggcccaaggccgacgccgcactgcacctgcacgagctgacc
cggcacctcgacctctccgcgttcgtgctctacgccgccatggcaggcgcggtcggcagc
ccaggccagggcaactacgccgcggccaacgccttcctcgacgcgctggccgaacgccgc
cgcgccgaggggctgcccgcgctgtcggtgtcgtggggctggtgggaaggcgacggcatg
gccaagctcgacggtgtcgatcagagccgcctccgccgcaacggcctgctgccgatggca
cccgaacgcgcggtcgccgaattgttcgacgcgctgcgcaccgacgacgcaaccctgctg
gtgaccaatgtggactggccgaggttcgtgcccgccttcaccaccacccggtcgagcgca
ctgctggaacccgtcaccgtgcgcgtcgcggctcccacagccacgcaggcggtcacggtg
gccgacgagccggacgccgtgtcggatctcctcgggcgactcgccggggccgacgcgacc
gaacgcgctcgcctgatgctggatctggtctgctcgcacgtggccgaggtcctcggctac
gactcctcggacacggtcgaggtctccaggggcttcctcgaactgggcttcgactcactc
acggcggtggaactgcgcaaccagctgaccgcgcggaccggactgcggctgccacccacg
ttgatcttcgactatccgagcccttccgcgctggcggactggctgaccacccaggtgctc
ggcgggtccggcaacggtggcgacccgagagaggccgaggtcagggggctgctcgcctcg
atcccgctcacccggctcgacgaagcaggtctgctcgacgacctcctcaggctcggcagg
ggcgcagagaacacggacgaaggacaggccaacggcgaggccgagcagctcgacgacctg
gatgtcgccgacctcgtccggctcgcaagggaagacctcgaccgatga
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