Spiractinospora alimapuensis: J4H86_17145
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Entry
J4H86_17145 CDS
T07850
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
saiu
Spiractinospora alimapuensis
Pathway
saiu00860
Porphyrin metabolism
saiu01100
Metabolic pathways
saiu01110
Biosynthesis of secondary metabolites
saiu01120
Microbial metabolism in diverse environments
saiu01240
Biosynthesis of cofactors
Module
saiu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
saiu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
saiu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
J4H86_17145
Enzymes [BR:
saiu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
J4H86_17145
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
J4H86_17145
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QVQ50618
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Position
3702049..3703707
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AA seq
552 aa
AA seq
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MNHQGVDVTSEGEASVADGHVAAVGAGPGDPELLTLRGAALLERADVVFGLSEDEEMASF
RDALLQHRGANTRVLGPDEYGDDPDALAVAKAWEGKRVVRLYAGDPLLGGQVDNLADACR
AAGVEFELAPGLSAALTVPSYAGIPLMANNASETRLIDGSGDIAQLPGIERQDTTLVVLN
AQGEGDDPFFDRVTKPLVAAGRPTTTPIAVVRMGTTTKQTTVVSTLGKLASALRSTDAKG
HHVTRPATVIVGPGVRRQSDLTWFESRPLFGWRVLVPRTQAQAAGLTEQLRGYGAVPEQV
PTISVEPPRTPQQMERAVRGLVNGRYQWVAFTSTNAVRAIRERVEEYELDARAFAGVRVA
AVGEATADALRDFGIEPDLMPAPETQSSTGLVEVWPPYDPELDPIERVLLPRADIATETL
SAGVQELGWAVDDVTAYRTVRAAPPPAPVREAIKGGGFDAVLFTSSSTVRNLVGIAGKPH
AATVIAVIGRETEKTALEHGLRVDVVAERASVASLAEGLAAFGTKRRQEAIDAGKPVLRP
SQKRRGRRRKTV
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgaaccatcagggagtagacgtgacaagcgagggtgaggcatccgtcgccgacggccac
gtggccgctgtgggtgcggggccgggtgacccggagctgctcacgctgcgcggagccgcg
ctgctggagcgggccgatgtcgtgttcggcctcagcgaggacgaggagatggcgtcgttc
cgggacgcgctgctgcagcaccgcggcgcgaacacccgcgtcctggggcccgatgagtac
ggcgacgaccccgacgccctggccgtggccaaggcctgggagggcaagcgggtggtacgg
ctctacgccggtgacccgctcctgggtggccaggtggacaacctcgccgacgcgtgccgc
gcggccggggtggagttcgagctcgccccggggctgtccgccgccctcaccgtgccgtcc
tacgccggaatccccctgatggcgaacaacgcgtcggagacgcggctgatcgacgggagc
ggcgacatcgcccagcttcccggcatcgagcggcaggacaccacactcgtcgtcctcaac
gcccagggcgagggggacgaccccttcttcgaccgcgtcaccaagccgttggtcgccgcc
ggacgccccacgaccacacccatcgcggtcgtgcgcatgggcaccaccacgaagcagacc
accgtggtctcgacactgggcaagctcgccagtgccctgcggtccacggacgccaagggc
caccacgtcacccgccccgcgaccgtcatcgtcggcccgggcgtgcgccgccagtccgac
ctgacgtggttcgagagccggccgctcttcggatggcgggtcctggtgccgcgcacccag
gcccaggccgccggactgaccgagcagctccgtggctacggggcggttcccgaacaggtt
cccactatctcagtggagccgccgcggaccccacagcagatggagcgcgccgtccgtggc
ctggtgaacggccggtaccagtgggtggccttcacctccaccaacgccgtccgcgccatc
cgggaacgtgtcgaggaatacgagctggacgcgcgcgcgttcgccggggtacgggtcgcg
gcggtcggtgaggcgacggccgacgcgctgcgggacttcgggatcgaacccgacctgatg
ccggccccggagacccagtccagcaccgggctggtggaggtctggccgccctacgacccg
gagctcgacccgatcgaacgggtgctgctgccgcgcgccgacatcgccaccgagacgctg
tccgccggagtgcaggagctcggttgggcggtcgacgacgtcaccgcctaccggaccgtg
cgcgccgcacccccgcccgcgcccgtgcgggaggccatcaagggcggcggtttcgacgcc
gtcctcttcacctcctcctcgacggtgcgcaacctggtcggtatcgccggcaagccgcac
gcggccaccgtcatcgccgtgatcggccgcgagacggagaagaccgcgctcgaacacggc
cttcgagtggacgtggtcgccgaacgcgcgtccgtggcctcactcgcggaaggactcgcc
gccttcggaacgaagcggcgccaggaggccatcgacgccggcaagcccgtgctgcgtccc
agccagaagcgacgcggacgccgacgcaagacagtgtga
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