Streptomyces noursei NK660: DC74_3963
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Entry
DC74_3963 CDS
T03082
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00860
Porphyrin metabolism
salu01100
Metabolic pathways
salu01110
Biosynthesis of secondary metabolites
salu01120
Microbial metabolism in diverse environments
salu01240
Biosynthesis of cofactors
Module
salu_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
salu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
salu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
DC74_3963
Enzymes [BR:
salu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
DC74_3963
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
DC74_3963
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AIA04452
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Position
complement(4495682..4497340)
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AA seq
552 aa
AA seq
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MNPTAPNHSASGQVTFLGAGPGDPGLLTLRAVEALASADVLIADPQVLDVVRVHARAQVD
TPLQASADAASIPGSPPGVSALRDTANLVMAAARAGKRVVRAVTGDPGLDGYVAEEMLAC
AAEGIVFEVVPGIAAAVGVPAYAGVPLRDAQGTDVRFVDARSADDRCWTELGASDATAVV
STTLDSVAAAAGELVAGGRKPDTPMTVTVAGTTTRQRTWTATLGSVAQVLKAAKVLPSPD
GGQPVIAVVGERSAAAQRDQLSWFENKPLFGWRVLVPRTKEQAASLSDQLVSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTARALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALAEFGAARRDAALEAGDPVTRPS
ERRPGSRRRARS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccaaaccactccgcctccggtcaggtcaccttcctgggtgccggg
ccgggagacccgggtctgctgacgttgcgcgccgtcgaggcgctggcctccgcggacgtc
ctcatcgccgacccgcaggtcctggacgtcgtgcgtgtgcacgcacgcgcacaggtggac
actccgttgcaggcgtcagctgacgcggcgtcaatccccggcagtcccccgggcgtttcc
gcccttcgggacaccgccaatcttgtcatggcggccgcgcgcgccggcaagcgggtcgtc
cgtgcggtgaccggagaccccggcctcgacggctacgtcgcagaggagatgctggcgtgc
gccgccgagggcatcgtcttcgaggtcgtacccggcatcgccgccgcggtcggcgtgccc
gcgtacgccggcgtgccgctgcgcgacgcccagggcaccgacgtccgcttcgtcgacgcc
cgcagcgccgacgaccgctgctggaccgagctgggtgccagcgacgccaccgcggtggtc
tccaccaccttggactcggtggccgcggccgccggggaactggtggccgggggccgcaag
ccggacaccccgatgaccgtcacggtcgccggcaccaccacccggcagcgcacctggacc
gccaccctcgggagcgtcgcccaggtgctcaaggccgccaaggtgctgccgtcgccggac
ggcgggcagccggtcatagccgtggtcggcgagcgcagtgccgcagcccagcgcgaccag
ctctcgtggttcgagaacaagccgctgttcggctggcgggtgctggtcccgcggaccaag
gagcaggccgcgtcgctctccgaccagctcgtctcgtacggcgcggtgccgcacgaggtc
ccgaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcggtcaagggc
ctggtcaccggccgctacgagtggatcgccttcacctcggtcaacgccgtcaaggcggtc
cgggagaagttcgaggagtacgggctggacgcgcgggcgttcgccgggatcaaggtcgcg
gcggtcggcgagcagaccgccagggcgctggtcgccttcggcgtgaagccggacctggtg
cccagtggcgagcagtccgcggccgggctgctggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagacgctggtg
gcggggctgatcgagctggggtgggaggtcgacgacgtcaccgcctaccggaccgtgcgc
gcctcgccgccgccggccgagacccgtgaggcgatcaagggcggcggcttcgacgccgtg
ctgttcacctcgtcctcgaccgtgcgcaacctcgtcggcatcgccggcaagccgcacaac
gtcaccgtgatcgcctgcatcggtccggccaccgccaagacggccgaggagcacgggctg
cgggtggacgtgatgtcgcccgagccgtcggtgcacaagctggccgaggcgctcgcggag
ttcggggcggcgcggcgcgacgcggcgctggaggccggcgacccggtcacccgccccagc
gagcgccggccgggctcgcgccgacgggcccgtagctga
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