Streptomyces alboniger: CP975_20060
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Entry
CP975_20060 CDS
T06908
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
salw
Streptomyces alboniger
Pathway
salw00860
Porphyrin metabolism
salw01100
Metabolic pathways
salw01110
Biosynthesis of secondary metabolites
salw01120
Microbial metabolism in diverse environments
salw01240
Biosynthesis of cofactors
Module
salw_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
salw_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
salw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CP975_20060
Enzymes [BR:
salw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CP975_20060
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CP975_20060
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QEV19486
UniProt:
A0A5J6HH82
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Position
4476222..4477880
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AA seq
552 aa
AA seq
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MSPTSNLPGIPAHGHVTFLGAGPGDPGLLTLRAVEALARADVLIAEPDVLDVVRVHAKGG
VDTPLPPTTDDTSATADTTTIRVAANLVMEAARGGKRVVRAVSGDPGLDTDAAQEMLACA
AEGISFEVVPGIAAAVGVPAYAGVPLRDSQGADVRFVDARTASDRCWSEVGASDGTAVVS
TSLDSVAAAAGELVAAGRKPDTPMTVTIAGTTTRQRTWNATLGTIAQVLKQAKVLPSPDG
GQPVIAVVGERSAAAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVPHEVP
TIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAA
VGEQTAAALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVA
GLIDLGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNV
TVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAQALADFGSQRRAAALDAGDPVTRPSE
RRPGSRRRRTAP
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccacctcgaaccttcccggcattcccgcacacgggcacgtcaccttcctgggt
gccggacccggagatccgggactgctgaccctgcgcgccgtcgaggcgctggcccgagcg
gatgtgctgatcgccgagcctgatgtgctcgacgtcgtccgtgtgcatgccaagggaggt
gtggacacacccctgccgccgaccactgacgacacgtcagcaaccgcggacacgacgacg
atccgagtcgccgccaatcttgtcatggaggccgcgaggggcggcaagcgggtcgtgcgc
gcggtcagcggcgaccccggcctcgacacggacgcggcgcaggagatgctcgcctgcgcc
gccgagggcatctccttcgaggtcgtgccgggcatcgcggccgcggtcggtgtgcccgcg
tacgccggtgtgccgctgcgggactcgcagggcgcggacgtccgcttcgtcgacgcccgt
acggcgtccgaccgctgctggagcgaggtcggcgcgtccgacgggaccgcggtggtctcc
acgtcgctcgactccgtcgcggcggccgcgggcgagctggtggccgcgggccgcaagccg
gacaccccgatgacggtgaccatcgccggtacgacgacgcgccagcgcacctggaacgcg
acgctcggcaccatcgcgcaggtcctcaagcaggcgaaggtgctgccctcgcccgacggg
gggcagcccgtcatagccgtggtcggcgagcgctccgccgccgcccagcgcgaccagctg
tcgtggttcgagtcgaagcccctcttcggctggcgcgtgctcgtcccgcgtacgaaggag
caggcggcctcgctctccgaccagctgcgctcctacggcgcggtgccgcacgaggtgccg
accatcgcggtcgagccgccgcgcacgccccagcagatggagcgcgcggtcaagggcctg
gtcaccgggcggtacgagtggatcgccttcacgtccgtcaacgcggtgaaggcggtgcgg
gagaagttcgaggagtacgggctcgacgcgcgtgccttcgccgggatcaaggtcgcggcc
gtcggtgagcagacggccgccgcgctgatcgccttcggcgtcaagcccgacctggtgccg
agcggtgagcagtcggccgcgggcctcctggaggactggccgccctacgacccggtcttc
gacccgatcgaccgcgtcttcctgccgcgggccgacatcgccacggagacgctggtcgcc
ggtctcatcgacctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgcgcc
tcgccgccgccggcagagacgcgggaggccatcaagggcggcggtttcgacgccgtgctc
ttcacgtcctcctcgaccgtgcgcaacctcgtcggcatcgcgggcaagccgcacaacgtg
acggtcatcgcgtgtatcggccccgccaccgcgaagacggcggaggagcacgggctgcgg
gtggacgtgatggctccggagccctcggtgcacaagctggcccaggcgctggccgacttc
ggttcgcagcggcgggccgcggcgctggacgccggggaccccgtgacgcggccgagcgag
cgtcggcccggttcgcgtcggcgacgcaccgcgccgtag
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