Streptomyces ambofaciens: SAM23877_5057
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Entry
SAM23877_5057 CDS
T04055
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
samb
Streptomyces ambofaciens
Pathway
samb00020
Citrate cycle (TCA cycle)
samb00630
Glyoxylate and dicarboxylate metabolism
samb00785
Lipoic acid metabolism
samb01100
Metabolic pathways
samb01110
Biosynthesis of secondary metabolites
samb01120
Microbial metabolism in diverse environments
samb01200
Carbon metabolism
samb01210
2-Oxocarboxylic acid metabolism
Module
samb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
samb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
samb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SAM23877_5057 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
SAM23877_5057 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SAM23877_5057 (kgd)
Enzymes [BR:
samb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SAM23877_5057 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SAM23877_5057 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SAM23877_5057 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SAM23877_5057 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AKZ58102
UniProt:
A0A0K2AZ52
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All DBs
Position
complement(5357993..5361871)
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AA seq
1292 aa
AA seq
DB search
MIPAVHHLVKRKRAVLAVSPQSPSNSSISTDTDQAGKNPAAAFGANEWLVDEIYQQYLQD
PNSVDRAWWDFFADYKPGAAAAQPASGTANESAGTPQAAPAPPAQAPAPAQAQAAPAPAA
PAPAAPQPAPAAKPAAQPAAAPAAKPAQAQPAAKPAAKAAAPAKDAAAASEGPETVTLRG
PAAAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQ
AIKAMPAMNYSFGEKDGKPTLVKPAHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEF
WQAYEDIVRRARDGKLTMDDFSGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPA
EFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDEIFEAL
RIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDIT
EHGLTLWDLEREFAVGGFAGKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDR
IERSHTKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAA
ESRLDEVVIGMAHRGRLNVLANVVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTF
TGLDGEQINVSLVANPSHLEAVDPVLEGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQ
GVVAETLNMSQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNG
DDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVR
KLYTESLIGRGDITLEEAEQALQDYQGQLEKVFTEVREAVSQPSAAEPSDPQAEFPVAVN
TAVSAETVKRIAESQVNIPDHVTIHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLE
GVPVRLTGQDSQRGTFGQRHAVVIDRETGDEFTPLLYLSEDQARYNVYNSLLSEYAVMGF
EYGYSLARPDALVMWEAQFGDFVNGAQTVVDEFISSAEQKWNQTSGVTLLLPHGYEGQGP
DHSSARPERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAA
ASKAEEFTTGQFRPVIGDDSVDAAAVRKVVFCAGKVYYDLEAERKKRGVTDTAIIRIERL
YPLPGTELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLR
RISRPHGSSPAVGSAKRHQAEQEQLVREVFEA
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
ttgattcccgctgtccaccatcttgtgaagcggaagagggcggttctcgccgtgtcgcca
cagtcccccagtaactcgagcatctcgaccgacaccgaccaagcgggcaagaaccccgct
gccgcgttcggtgccaatgagtggctcgtcgacgagatttatcagcagtacctccaggat
ccgaattccgtggaccgagcctggtgggacttcttcgccgactacaagcccggagcggcc
gcggcccagccggcttccggtaccgcgaacgagagcgcgggcacgccccaggccgccccc
gcgcccccggcgcaggctcccgccccggcccaggcccaggcggcacccgccccggcggct
cccgccccggcggctccccagccggcccccgccgcgaagccggccgcgcagcccgccgcc
gctccggcggccaagcccgcgcaggcccagcccgccgccaagcccgcggccaaggcggcc
gcccccgcgaaggacgccgccgcggcctccgagggccccgagacggtgacgctgcgcggc
ccggccgccgcggtcgcgaagaacatgaacgcctcgctggagctgcccacggccacgtcc
gtgcgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctc
aagcgcgcccggggcgggaagatctccttcacgcacctgatcggctacgcgatggtgcag
gccatcaaggccatgccggcgatgaactactcgttcggcgagaaggacggcaagccgacc
ctcgtcaagccggcgcacgtcaacctcggtctcgccatcgacctggtcaagcccaacggc
gaccgccagctcgtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgagttc
tggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatggacgac
ttctccggcgtcacggtctccctgaccaaccccggcggcctcggcaccgtccactcggtg
ccgcgcctgatgcccggccagtcggtcatcatgggcgtcggctcgatggactacccggcg
gagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacg
ctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgc
caggtcgccaacctcctcctcggcgagaacggcttctacgacgagatcttcgaggcgctg
cgcatcccctacgagccggtccgctggctcaaggacatcgacgcctcgcacgacgacgac
gtcaccaaggccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtc
atggccgacaccgacccgctggagtaccagcagcgcaagcaccccgacctggacatcacc
gagcacgggctcaccctgtgggacctggagcgcgagttcgcggtcggcggtttcgccggc
aagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcacc
accggcgtcgagttcatgcacatccaggacccgaagcagcgcaagtggatccaggaccgc
atcgagcgctcgcacaccaagccggagcgcgaggagcagctgcgcatcctgcgccggctg
aacgcggcggaggccttcgagaccttcctgcagaccaagtacgtcggccagaagcgcttc
tccctggagggcggcgagtccgtcatcccgctgctggacgcggtcatcgactcggcggcg
gagtcccggctggacgaggtcgtcatcggcatggcccaccgcggccggctgaacgtgctg
gccaacgtcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgac
ccgaagtcgatgcacggctccggtgacgtgaagtaccacctgggcgccgagggcaccttc
accgggctggacggcgagcagatcaacgtctcgctggtcgccaacccctcgcacctggag
gcggtggacccggtcctggagggcgtcgcgcgcgccaagcaggacatcatcaacaagggc
ggcacggacttcaccgtcctgccggtggcgatccacggcgacgcggccttcgcgggccag
ggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacg
gtccacgtcgtcatcaacaaccaggtcggcttcaccgccgcgccggagtcctcgcgctcg
tcgatgtacgccaccgacgtggcccgcatgatcgaggcccccatcttccacgtgaacggc
gacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttc
aacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggac
aacccggccttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgc
aagctgtacaccgagtccctcatcggtcgcggcgacatcaccctggaggaggccgagcag
gcgctccaggactaccagggccagctggagaaggtcttcaccgaggtccgcgaggccgtc
tcgcagccgtccgccgcggagccctcggacccgcaggccgagttcccggtcgccgtgaac
accgcggtcagcgccgagaccgtcaagcggatcgccgagtcccaggtcaacatccccgac
cacgtcaccatccacccgcgtctgctgccgcagctgcagcgccgcgcggcgatggtcgag
gacggcacgatcgactggggcatgggcgagaccctcgccgtcggctccctcctcctggag
ggcgtgccggtccgtctgacgggccaggactcccagcgcggcaccttcggccagcgtcac
gcggtcgtcatcgaccgggagaccggtgacgagttcacgccgctgctgtacctgtccgag
gaccaggcccggtacaacgtctacaactcgctgctctccgagtacgcggtgatgggcttc
gagtacggctactcgctggcccgcccggacgcgctggtgatgtgggaggcgcagttcggc
gacttcgtcaacggcgcgcagacggtcgtggacgagttcatctcgtcggccgagcagaag
tggaaccagacgagcggcgtcacgctcctgctcccgcacggctacgagggccagggcccg
gaccactcctcggcccgcccggagcgcttcctccagctctgcgcgcagaacaacatgacg
gtcgcgatgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaac
ccgcaccacaagccgctggtggtcttcaccccgaagtcgatgctgcgcctgaaggccgcg
gcctcgaaggcggaggagttcacgacgggccagttccgcccggtcatcggcgacgactcg
gtcgacgccgccgcggtcaggaaggtcgtcttctgcgcgggcaaggtctactacgacctc
gaggccgagcggaagaagcgcggcgtcacggacacggccatcatccgcatcgagcgcctg
tacccgctgccgggtaccgagctccaggcggagatcgccaagtacccgaacgccgagaag
tacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaac
ctgatcgaccacctggacctggcggtcggcgccgacgtgccgcacggcgagcgtctgcgc
cgcatctcgcggccgcacggctcgtccccggccgtgggttccgcgaagcggcaccaggcc
gagcaggagcagctggtgcgcgaggtgttcgaggcctga
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