KEGG   Streptomyces angustmyceticus: K7396_10520
Entry
K7396_10520       CDS       T07927                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
sanu  Streptomyces angustmyceticus
Pathway
sanu00290  Valine, leucine and isoleucine biosynthesis
sanu00660  C5-Branched dibasic acid metabolism
sanu01100  Metabolic pathways
sanu01110  Biosynthesis of secondary metabolites
sanu01210  2-Oxocarboxylic acid metabolism
sanu01230  Biosynthesis of amino acids
Module
sanu_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sanu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    K7396_10520 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    K7396_10520 (leuC)
Enzymes [BR:sanu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     K7396_10520 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     K7396_10520 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: UAL66920
LinkDB
Position
complement(2365505..2366935)
AA seq 476 aa
MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRQVRRTDLTIAT
EDHNTPTLDIDKPIADPVSRTQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLAPFKTMAITVDGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDATTF
DYLQGRDHAPQGADWDAAVAYWKTLRTDDDAVFDAEVRIDASELAPFVTWGTNPGQGAPL
SASVPDPASYEDASERYAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRSAAA
ILEGRRVADDVRMLIVPGSVRVSLEAVAEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVAVATPAGV
NT seq 1431 nt   +upstreamnt  +downstreamnt
atgggacggacactcgcggagaaggtctgggacgatcatgtcgtccggcgcgcggaaggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtcaccagcccgcaggcg
ttcgacggcctccgcaaggccggccgccaggtgcgccggacggacctgaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
acccagctggagacgctgcgcaagaactgtgccgagttcggcgtccggctgcacccgctg
ggcgatgtcgagcagggcgttgtccacgtcgtgggaccccagttgggactgacccagccc
ggcaccaccgtggtctgcggtgacagccacacctccacccacggagccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtcctggccacccagacgctgccgctg
gcccccttcaagaccatggcgatcaccgtcgacggcgagctgcccgagggtgtcaccgcc
aaggacctcatcctggcgatcatcgccaggatcggcaccggcggcggccagggctacgtc
ctggagtaccggggcgaggccatcgagaagctgtcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggcgggcgcgcgggccggcatgatcgcccccgacgcgaccaccttc
gactacctgcagggccgtgatcacgccccgcagggcgcggactgggacgccgcggtcgcg
tactggaagaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtgcgcatcgac
gcctccgaactggccccgttcgtcacctggggcaccaaccccgggcagggcgccccgctt
tcggccagcgtccccgacccggcttcgtacgaggacgcctcggaacgctatgccgccgaa
aaggccctggagtacatggggttgacggcgggtcagccgctgcgggacatcaaggtggac
accgtcttcgtaggttcgtgcaccaacggccggatcgaggacctgcgctcggccgccgcg
atcctggagggccgcagggtcgccgacgacgtccgcatgctgatcgtgcccggctcggtc
cgggtctcgctggaggccgtcgccgaggggctggacaaggtcttcaccgcggcgggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggcgccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggg
cgtacgcacctggtctcgccgcaggtcgccgccgcaacggcggttctcggccatctggcc
tcaccggccgacctgtccgatgtcgccgtcgccacgcccgcgggagtctga

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