Streptomyces angustmyceticus: K7396_19470
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Entry
K7396_19470 CDS
T07927
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sanu
Streptomyces angustmyceticus
Pathway
sanu00860
Porphyrin metabolism
sanu01100
Metabolic pathways
sanu01110
Biosynthesis of secondary metabolites
sanu01120
Microbial metabolism in diverse environments
sanu01240
Biosynthesis of cofactors
Module
sanu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sanu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sanu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
K7396_19470
Enzymes [BR:
sanu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
K7396_19470
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
K7396_19470
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UAL68428
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Position
4393324..4394982
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AA seq
552 aa
AA seq
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MNPTAPNHSASGQVTFLGAGPGDPGLLTLRAVEALASADVLIADPQVLDVVRVHARAQVD
TPLQASADEASIPVTPNGVSALRDTANLVMAAARAGKRVVRAVTGDPGLDGYVAEEMLAC
AAEGIVFEVVPGIAAAVGVPAYAGVPLRDAEGTDVRFIDARTADARCWSEVGASDATAVV
STSLDSVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGSVAQVLKAAKVLPSPD
GGQPVIAVVGERSAAAQRDRLSWFESKPLFGWRVLVPRTKEQAASLSDQLVSYGAVPHEV
PTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVA
AVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLV
AGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHN
VTVIACIGPATAKTAEEHGLRVDVMSPEPSVHKLAEALADFGAARRDAAVEAGDPVTRPS
ERRPGSRRRARS
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccaaaccactccgcctccggtcaggtcaccttcctgggtgccggg
ccgggagacccgggtctgctgacgctgcgtgccgtggaggcgctggcctccgcggacgta
ctgatcgccgacccgcaggtgctggacgtcgtgcgcgtgcatgcccgcgcacaggtggac
acaccactgcaggcgtcagctgacgaggcgtcaatccccgtcacccccaatggcgtttcc
gcccttcgggacaccgccaatcttgtcatggcggcggcccgtgcgggcaagcgggtcgtc
cgtgccgtcaccggggatcccggtctcgacggctacgtcgccgaggagatgctggcctgc
gccgccgagggcatcgtcttcgaggtcgtgccgggcatcgccgcggccgtcggcgtgccc
gcgtacgccggtgtcccgctgcgggacgccgagggcaccgacgtccgcttcatcgatgcc
cgcaccgccgacgcgcgctgctggtccgaggtgggtgccagtgacgccaccgccgtcgtc
tccacctccctcgactcggtggccgcggccgccggggagctggtgtcggccggccgcaag
ccggacaccccgctgaccgtcaccgtcgccggcaccaccacccgccagcgcacctggacc
gccaccctcgggtcggtcgcccaggtcctcaaggccgccaaggtgctgccctcgccggac
ggcggccagccggtcatagccgtggtcggtgagcgcagtgccgcggcccagcgcgaccgt
ctgtcgtggttcgagtccaagccgctcttcggctggcgggtgctcgtgccgcggacgaag
gagcaggccgcgtcgctctccgaccagctggtgtcgtacggcgcggtgccgcacgaggtc
ccgaccatcgcagtggagccgccgcgcaccccgcagcagatggagcgcgcggtcaagggc
ctggtcaccgggcgctacgagtggatcgccttcacctcggtcaacgccgtcaaggccgtc
cgggagaagttcgaggagtacggcctggacgcccgcgccttcgccgggatcaaggtcgcc
gcggtcggcgagcagaccgccaaggcgctggtcgccttcggcgtgaagcccgacctggtg
ccgagcggcgagcagtcggccgccggcctgctggaggactggccgccctacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagaccctggtc
gccgggctgatcgagctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgt
gcctcgccgccgccggccgagacccgcgaggcgatcaagggcggcgggttcgacgccgtg
ctgttcacctcgtcgagcaccgtgcggaacctcgtcggcatcgccggcaagccgcacaac
gtgaccgtgatcgcctgtatcggtccggccaccgccaagaccgcggaggagcacgggctg
cgggtcgatgtcatgtcgcccgagccgtcggtgcacaagctggccgaggcgctggcggac
ttcggtgcggcgcggcgcgacgccgccgtcgaggccggggacccggtcacccggccgagc
gagcggcgtcccgggtcgcgcagacgcgctcgcagctga
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