Salinispora arenicola: Sare_0428
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Entry
Sare_0428 CDS
T00613
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
saq
Salinispora arenicola
Pathway
saq00860
Porphyrin metabolism
saq01100
Metabolic pathways
saq01110
Biosynthesis of secondary metabolites
saq01120
Microbial metabolism in diverse environments
saq01240
Biosynthesis of cofactors
Module
saq_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
saq_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
saq00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Sare_0428
Enzymes [BR:
saq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Sare_0428
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Sare_0428
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ABV96357
UniProt:
A8LZJ1
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Position
488900..490480
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AA seq
526 aa
AA seq
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MTRSRKPVGRIAFVGAGPGDPGLLTRRGYDALVNADQVVYDRGVPESLLDVVRAQAKQDA
QLTLAEGGSGDVAKVLISAARSGLNAVHLVAGDPFGHGSVVKEVQAVARTAGHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVNTLDFEALAAAVTRGPLALAADAGDLAAIRDGLL
AAGVDDTTAVGVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTLGDGVGQRDKLSWWE
NRPLYGWKVLVPRTKEQAGVMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGDATADAVRAFGIRPELVPAGEQ
SSEGLLAEFSPHDEVLDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVSVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAGYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcagccgtaagcccgtaggccgcatcgcgttcgtcggggccggccccggcgac
ccgggcctgctgacccgccgggggtacgacgccctggtcaatgccgaccaggtggtatat
gaccggggagttcccgagtcgctgctcgacgtcgttcgcgcccaggcgaaacaggacgcc
cagctcaccctggctgagggcgggtccggcgacgtggcgaaggtgctgatctcggcggcc
cgttccgggctgaacgcggtgcacctggtcgccggtgacccgttcggccacgggtcggtg
gtcaaggaggtgcaggcggtcgcgcggaccgccgggcacttcgaggtggtcccgggcgtc
ggccaggcagagggggtggcgacctacgcgggtgtgccgctacccggagtccgcacagcg
gctgacgtcgaggacgtcaacacgctggacttcgaggcgctggccgccgccgtcacccgg
gggccgctggcactcgcggcggacgccggggaccttgccgcgatccgggacgggttgctc
gccgccggggtcgacgacacaacggccgtgggggtgaccggtgacggcaccggtgagacc
cagtacacgaccacgtcgaccgtggactccttcgtcgcggcggcgctcggcttcaccggc
cgggtcgtactcacccttggcgacggggttggccagcgggacaagctcagctggtgggag
aaccgcccgctgtacggctggaaggtgctcgtaccgcggacgaaggaacaggccggcgtg
atgagtgcccggctgcgcgcgtacggcgcgattccctgtgaggtaccgaccatcgcggtc
gagccgccgcgtactcccgcgcagatggagcgggcggtcaaggggctggtcgacggccgg
tacgcctgggtgatcttcacgtcggtgaacgcggtccgggcggtctgggagaagttcgcc
gagcacggcctcgacgcccgacacttcggcggcgtgaagatcgcctgtatcggtgacgcg
accgccgacgcggtccgcgccttcgggatcaggccggagctggtccccgccggtgagcag
tcgtcggagggcctgttggccgagttctcgccgcacgacgaggtactcgacccggttggt
cgggtgctgctgccgcgcgccgacatcgctaccgagacgttggccgccgggctcaccgag
cgaggctgggaggttgacgacgtcaccgcgtaccggacggtccgggcggcgccgccgccg
gccgagatccgcgacgcgatcaagtcgggtgggttcgacgcggtgctcttcacctcgtcg
tccacggtccggaacttggtcggcatcgccgggaagccgcacgcgcgtaccgttgtttcg
gttatcgggcccaagacggcggagaccgccaccgagttcggccttcgggtcgacgtgcag
cctccgcacgcctcggtccctgacttggtggaggcgctggccggctacgccgtcgagctg
cgcgagaagctcgccgctatgccggcgaagcagcgtcgcggctcgaaggtgcaggggccg
accgccctcaggttccgctga
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