Streptomyces aquilus: EJC51_27760
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Entry
EJC51_27760 CDS
T07011
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
saqu
Streptomyces aquilus
Pathway
saqu00860
Porphyrin metabolism
saqu01100
Metabolic pathways
saqu01110
Biosynthesis of secondary metabolites
saqu01120
Microbial metabolism in diverse environments
saqu01240
Biosynthesis of cofactors
Module
saqu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
saqu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
saqu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
EJC51_27760
Enzymes [BR:
saqu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
EJC51_27760
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
EJC51_27760
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AZP19527
UniProt:
A0A3Q9C1D9
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Position
6030574..6032280
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AA seq
568 aa
AA seq
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MSPTTLPAAGPEHGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEHEVLDVVRVHARSG
VAVVNTEPGSSSDPVPGTGAPQLTVVDGSSATAGVPAVRDAAHLVMEAARGGRRVVRAVS
GDPGLDAYAAEEMLACARAGVPFEVVPGVAAAVGVPAYAGVPLRDAEGADVRFVDARTAS
DRCWTEVGASDGTVVVSTTLDSVAAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWTATLG
TIAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDQLSWFENKPLFGWRVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLK
RRAAAVEAGDPVTRPSERRPGARRRRTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcctgccgccggtcctgagcacgggcacgtcaccttcctgggt
gccggacccggggatccgggactactgactctgcgcgccgtggaggcgctggcgagcgcg
gacgtcctcgtcgccgagcacgaggtgctcgacgtcgtacgcgtccacgcccgttcgggc
gtcgccgtcgtgaacacggagccggggtcctcgtcggacccggtcccgggcacaggcgcg
cctcagctgacggttgttgacggttcgtcagcaaccgcgggtgtccccgccgtgagggat
gccgcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtgtcc
ggggaccccgggctcgacgcgtacgccgccgaggagatgctggcgtgcgcccgcgccggg
gtgcccttcgaggtggttcccggtgtcgcggccgcggtcggcgtgcccgcctacgccggt
gtgccgctgcgcgacgccgagggcgcggacgtgcggttcgtggacgcccggaccgcttcc
gaccggtgctggacggaggtgggggcctcggacggcacggtcgtggtgtcgacgaccctc
gactcggtcgcggcggcggccggcgagctggtggccgcgggccgcaagccggacaccccg
atgacggtcacggtcgccggtacgaccacgcgccagcgcacctggacggcgaccctgggc
accatcgcccagacgctcaagcaggccaaggtgctgccctcgcccgagggcgggcggccg
gtgatagccgtggtcggtgagcgttccgccgccgcccagcgcgaccagctgtcgtggttc
gagaacaagcccctcttcgggtggcgggttctcgtgccgcgtacgaaggagcaggcggcc
tcgctctccgaccagctgcgctcctacggcgctgtgccgcacgaggtgccgaccatcgcc
gtcgagccgccgcgcacgccccagcagatggagcgggccgtcaaggggctcgtgaccgga
cgctacgagtggatcgccttcacctccgtcaacgcggtcaaggccgtccgcgagaagttc
gaggagtacgggctcgacgcccgggccttcgcgggcatcaaggtggccgcggtgggtgag
cagaccgcgaaggcgctcatcgcgttcggtgtgaagccggatctggtgccgagcggtgag
cagtcggcggcggggctccttgaggactggccgccgtacgaccccgtcttcgacccgatc
gaccgggtcttcctgccgcgtgccgacatcgccaccgagacgctggtggccgggctgatc
gagctcgggtgggaggtcgacgacgtcaccgcctaccggaccgtgcgggcctcgccgccg
ccggcggagacgcgggaggcgatcaagggcggtggcttcgacgccgttctcttcacgtcg
tcctcgaccgtgcggaacctggtggggatcgccggcaagccgcacaacgtgaccgtgatc
gcgtgtatcgggccggcgacggcgaagacggccgaggagcacgggctgcgggtggatgtg
atggctccggagccgtccgtgcacaagctcgcggaggcgctggccgacttcgggctgaag
cggcgggcggcggcggtcgaggccggggatccggtgacacggccgagtgagcggcggccg
ggggcgcggcggcggcgtacgacctga
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