Streptomyces argyrophyllae: HKX69_14970
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Entry
HKX69_14970 CDS
T09378
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sarg
Streptomyces argyrophyllae
Pathway
sarg00860
Porphyrin metabolism
sarg01100
Metabolic pathways
sarg01110
Biosynthesis of secondary metabolites
sarg01120
Microbial metabolism in diverse environments
sarg01240
Biosynthesis of cofactors
Module
sarg_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sarg_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sarg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HKX69_14970
Enzymes [BR:
sarg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HKX69_14970
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HKX69_14970
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-ProteinID:
QJS10648
UniProt:
A0A6M4PHC6
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Position
complement(3385352..3387061)
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AA seq
569 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALSNADVLVAEHEVLDVIRTHARHGV
SVVQTDADCAAMSPPGTGTPQLTVVDGTSAPVAVPPPARDAAHLVMEAARGGRRVVRAVS
GDPGLDTYAAEEMLACAAAGVPFEVVPGVATAVGVPAYAGVPLRDAQGADVRFVDARTAS
ERCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLG
TIAQTLKQAKVLPSPDGGRPVIAVVGERSAAARRDQLSWFESKPLFGWKVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGMK
RRAAALEAGDPVTRPSERRPGARRRRSTT
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccacccttcccgccggtccggaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtggaggcgctgtcgaacgcggac
gtcctggtcgccgagcacgaggtgctcgacgtcatccggacgcacgcgcggcacggcgtc
tccgtggtgcagacggacgcggactgcgccgcgatgtccccgccgggcacgggcacgcca
cagctgacggtcgttgacggcacgtcagcgcccgtcgccgtcccgccccccgcccgggat
gccgctcatcttgtcatggaggccgcacggggcggcaggcgggtcgtccgtgcggtgtcc
ggggaccccggactcgatacgtacgcggcggaggagatgctcgcctgtgccgccgccggg
gtgcccttcgaggtcgtccccggtgtcgcgacggcggtcggcgtgcccgcgtacgccggt
gtgccgctgcgggacgcgcagggcgcggacgtccgcttcgtggacgcccggaccgcctcc
gaacggtgctggacggaggtgggcgcgtcggacggcacggtggtcgtctcgacgaccctg
gactccgtcgccgccgcggcgggcgagctcgtctcggcgggccgcaagccggacaccccg
ctgacggtgacggtcgccggtacgacgacgcggcagcggacgtggacggcgacgctcggc
acgatcgcgcagacgctgaagcaggcgaaggtgctgccgtccccggacggcggccggccg
gtgatagccgtggtcggcgagcgttccgccgccgcccggcgcgaccagctgtcgtggttc
gagtccaagccgctgttcggctggaaggtgctcgtgccgcgcacgaaggagcaggcggcg
tcgctctccgaccagctgcggtcctacggcgcggtgccgcacgaggtcccgacgatcgcg
gtggagcccccgcgcaccccgcagcagatggagcgggcggtcaagggcctggtgacgggc
cgttacgagtggatcgcgttcacctccgtcaacgcggtgaaggcggtccgggagaagttc
gaggagtacggactcgacgcgcgcgccttcgcgggcatcaaggtggccgcggtgggcgag
cagaccgccaaggcgctggtcgccttcggcgtgaagccggacctggtgccgagcggcgag
cagtcggcggccggcctcctggaggactggcccccctacgacccggtcttcgacccgatc
gaccgcgtcttcctgccccgggccgacatcgcgaccgagaccctcgtcgccggtctgatc
gagctgggctgggaggtggacgacgtcacggcctaccggaccgtgcgcgcgtcgccgccg
ccggcggagacccgggaggcgatcaagggcggcggcttcgacgcggtcctgttcacgtcg
tcctccacggtccgcaacctggtcggcatcgcgggcaagccgcacaacgtcacggtgatc
gcgtgcatcggcccggcgacggccaagaccgccgaggaacacgggctgcgggtcgacgtg
atggccccggagccgtccgtgcacaagctggcggaggcgctggcggacttcggcatgaag
cggcgcgccgccgcgctggaggcgggcgacccggtgacccggcccagcgagcggaggccg
ggggcgcgcaggcggaggtctacgacctga
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