Streptomyces atratus: C5746_18505
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Entry
C5746_18505 CDS
T07374
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sata
Streptomyces atratus
Pathway
sata00860
Porphyrin metabolism
sata01100
Metabolic pathways
sata01110
Biosynthesis of secondary metabolites
sata01120
Microbial metabolism in diverse environments
sata01240
Biosynthesis of cofactors
Module
sata_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sata_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sata_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sata00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
C5746_18505
Enzymes [BR:
sata01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
C5746_18505
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
C5746_18505
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AXE78584
UniProt:
A0A2Z5JEC7
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Position
complement(4085179..4086849)
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AA seq
556 aa
AA seq
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MSPTGPAVSDFPALSAQGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEPDVLGVVRCH
ARAGVSAPELTVVDAQSTAAGVPVLRDAANLVMEAAKGGRRVVRAVSGDPGLDGNAGAEM
LACATAGIPFEVVPGVANVVGVPAYAGVPLRDAQGADVRFVDARTASERCWTEVGASDAT
AVVSTTLDSVASAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGTIAQVLKQAKVLP
SPDGHQPVIAVVGERSSAAQRDQLAWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTAAALVDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPSDTREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAEFGAQRREAAKVAGDPVT
RPSERRPGARRRRTTT
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgccgtatccgactttccggccctgtccgcacaagggcacgtc
accttcctcggcgccggtcccggcgacccgggactgctgactctgcgcgctgtcgaggcg
ctcgcgagcgcggacgtccttgtcgccgagccggacgttctcggcgtcgttcgctgccat
gcgcgggcaggcgtaagcgcgcctgagctgacggttgttgacgcacagtcaacagccgcc
ggtgtccccgttctcagggatgcggccaatcttgtcatggaggcagcgaagggcggcagg
cgggtcgtccgtgccgtctcgggcgacccgggactggacgggaacgccggcgccgagatg
ctcgcctgcgccaccgccggtatccccttcgaggtcgtaccgggtgtcgccaacgtcgtg
ggcgtgcccgcgtacgccggtgtgccgctgcgtgacgcgcagggtgccgacgtccggttc
gtcgacgcccgcaccgcctcggaacggtgctggaccgaggtcggcgcgagcgatgccacg
gcggtcgtctcgacgaccctcgactcggtggcctcggccgccggtgagctggtctcggcg
ggccgtaagcccgacaccccgctgaccgtgacggtggcgggtacgaccacccgccagcgc
acctggacggcgaccctcggcacgatcgcccaggtcctgaagcaggcgaaggtcctcccg
tcgccggacgggcatcagcccgtcatagccgtggtcggtgagcgcagctccgccgcccag
cgcgaccagctcgcgtggttcgagtccaagccgctgttcggctggaaggtgctcgtcccg
cgtaccaaggagcaggcggcgtcgctctccgaccagcttcgttcgtacggtgccgtgccg
cacgaggtcccgacgatcgccgtcgagccgccccgtacgccccagcagatggagcgagcg
gtcaagggcctggtcacgggccgctacgagtggatcgccttcaccagcgtcaatgccgtg
aaggccgtccgggagaagttcgaggagtacgggctcgacgcccgtgcctttgccgggatc
aaggtcgcggccgtcggcgagcagaccgccgccgcgctcgtcgacttcggtgtgaagccg
gacctggtgccgtccggtgagcagtccgccgccggtctgctggaggactggccgccgtac
gacccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgag
acgctggtggccgggctcatcgagctgggctgggaggtcgacgacgtcaccgcgtaccgc
acggtccgcgcctcgccgccgccctccgacacgcgtgaggccatcaagggcggcggtttc
gacgcggtgctcttcacctcgtcgtcgaccgtacggaacctcgtcggcatcgcgggcaag
ccgcacaacgtgacggtcatcgcgtgtatcggcccggcgacggccaagaccgccgaggag
cacggcctgcgcgtcgacgtcctgtcgccggagccttcggtgcacaagctggccgaggcc
ctcgccgagttcggtgcgcagcgccgggaggcggcgaaggtggccggtgacccggtgacg
cggccgagcgagcggcgtcccggtgcgcggcggcgtcgtacgacgacttga
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