Streptomyces autolyticus: BV401_25375
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Entry
BV401_25375 CDS
T04980
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sauo
Streptomyces autolyticus
Pathway
sauo00860
Porphyrin metabolism
sauo01100
Metabolic pathways
sauo01110
Biosynthesis of secondary metabolites
sauo01120
Microbial metabolism in diverse environments
sauo01240
Biosynthesis of cofactors
Module
sauo_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sauo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sauo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BV401_25375
Enzymes [BR:
sauo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
BV401_25375
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
BV401_25375
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AQA13259
UniProt:
A0A1P8XYH1
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Position
6252924..6254588
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AA seq
554 aa
AA seq
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MNPNAPNHPGCGHVTFLGAGPGDPGLLTLRAVEALAAADVLIADPQVLDVVRSHVRPGVA
ADAQGTPRQADTDGSSGTATVPVLRDSANLVMTAARGGKRVVRAVAGDPGLDGYAADEML
ACAAEGIVFEVVPGVAAAVGVPAYAGVPLRYAHSADVRFVDALTADERCWSEIGSSDATA
VVSATLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWSATLGTIAQVLKAAKVLPS
PQGGQSVIAVVGEQSAAGKRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRGYGAVPS
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTARSLIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVLKLAEALADFGAARRQAAIEAGEPVTR
PSERRPGSRRRARS
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaacgccccgaatcaccccggctgcggacacgtcacctttctcggtgccggc
cccggagatccgggcctgctgaccttgcgcgccgtggaggctctggccgccgctgacgta
ctgatcgccgaccctcaagtgctcgacgtggtgcgcagtcacgtcaggccgggcgtggcc
gcggacgctcagggcacgccgcggcaggcggacactgatgggtcatcaggcaccgccacc
gtcccggtactccgggacagcgccaatcttgtcatgacggccgcgcgcggcggcaagcgg
gtcgtccgcgcggtcgcgggcgaccccggcctcgacggatacgccgccgacgagatgctc
gcctgcgccgccgagggcatcgtcttcgaggtggtgcccggtgtggccgccgcggtgggc
gtgcccgcctacgcgggggtgccgctgcggtacgcccacagcgccgatgtgcgcttcgtg
gacgcgctgaccgccgatgagcgctgctggagcgagatcggctcgtccgacgcgaccgcc
gtggtctccgcgaccctggagacggtggccgccgccgcgggggagctggtggccgcgggc
cgtaagccggacaccccgctcaccgtcaccgtcgccggcaccaccacccgccagcggacc
tggtccgcgacgctggggaccatcgcccaggtgctgaaggcggcgaaggtgctgccgtcg
ccgcagggcgggcagtcggtgatagccgtggtcggggagcagagcgcggccggtaagcgc
gatcagctgtcttggttcgagtccaagccgctgttcggctggaaggtcctggtgccgcgc
accaaggagcaggccgcctcgctctcggaccagctgcgcggttacggcgcggtgcccagc
gaggtgccgacgatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcggtc
aagggcctggtcaccgggcgctatgagtggatcgccttcacctcggtcaacgcggtcaag
gcggtgcgggagaagttcgaggagtacgggctcgacgcccgcgcgttcgccgggatcaag
gtcgccgcggtgggcgagcagaccgcgaggtcgctgatcgacttcggggtgaagccggat
ctggtgcccagcggtgagcagtccgcggccgggctgctggaggactggccgccgtacgac
ccggtcttcgacccgatcgaccgggtcttcctgccgcgtgccgacatcgccaccgagacc
ctggtcgccgggctgatcgagctgggctgggaggtcgacgacgtgaccgcgtaccgcacc
gtgcgcgcctcgccgccgccggccgagacccgtgaggccatcaagggcggcgggttcgac
gcggtgctcttcacctcgtcgtccaccgtgcggaacctcgtcggcatcgcgggcaagccg
cacaatgtcactgtcatcgcctgtatcggcccggccaccgcgaagaccgcggaggagcac
ggcctgcgggtggacgtgctgtcgcccgagccctcggtgctcaagctggccgaggcgctc
gcggacttcggggcggcgcggcgccaggccgcgatcgaggccggggagccggtcacccgc
ccgagcgagcgacggcccggttcgcggaggagggcacgctcttga
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