Streptomyces buecherae: H7H31_14130
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Entry
H7H31_14130 CDS
T07050
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sby
Streptomyces buecherae
Pathway
sby00860
Porphyrin metabolism
sby01100
Metabolic pathways
sby01110
Biosynthesis of secondary metabolites
sby01120
Microbial metabolism in diverse environments
sby01240
Biosynthesis of cofactors
Module
sby_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sby_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sby_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sby00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
H7H31_14130
Enzymes [BR:
sby01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
H7H31_14130
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
H7H31_14130
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QNJ40845
UniProt:
A0A7G8KCR2
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Position
complement(3729420..3731084)
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AA seq
554 aa
AA seq
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MNPTAPNHPGCGHVTFLGAGPGDPGLLTLRAVEALATADVLIADAQVLDVVRPHVRPNVA
ADAQSALRQTEADGASVTAGVPVLRDTANLVMVAARGGKRVVRAVAGDPGLDGDAADEML
ACAAESIAFEVVPGVAAAVGVPAYAGVPLRDAQGTDVRFVDARHADERCWGEVGASDGTV
VVTATLETVAAAAGELVAAGRKPDTPLAVTVAGTTTRQRTWTATLGTIAQVFKSGKVLPS
ADGGQPVIAVVGERGAAERRDRLSWFESKPLFGWNVLVPRTKEQAASLSDQLRSYGAVPS
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTARSLVEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAEFGAARRAAAIEAGDPVTR
PSERRPGSRRRARS
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgaaccccaccgccccgaaccaccccggctgcgggcacgtcaccttcctcggtgccggg
ccaggcgatccgggcctgctgacgctgcgcgccgtggaggcactggctacagccgatgtg
ctgatcgccgacgcgcaggtgctcgacgtggtgcgtccgcatgtacggccgaatgtcgcg
gccgacgcgcagagcgcactacggcagaccgaggctgacggcgcgtcagtgaccgccgga
gtcccggtgcttagggataccgccaatcttgtcatggtggccgcgcgcggcggcaagcgg
gtcgtccgtgcggtcgccggcgacccggggctcgacggcgacgccgccgacgagatgctg
gcctgcgccgccgagtccatcgccttcgaggtggtgcccggcgtcgcggcggcggtcggc
gtgcccgcgtacgccggggtgccgctgcgcgacgcgcagggcacggacgtgcggttcgtc
gacgcccggcacgccgacgagcgctgctggggcgaggtcggcgccagcgacggcaccgtc
gtggtcaccgccacgctggagacggtcgccgccgccgccggcgagctggtggccgcgggc
cgcaagccggacacgccgctcgcggtgaccgtcgcgggcaccaccacgcggcagcgcacc
tggacggcgacgctcggcacgatcgcgcaggtcttcaagtcgggcaaggtgctgccgtcg
gccgacggcgggcagcccgtgatagccgtggtcggcgagcgcggcgcggccgagcggcgc
gaccgactgtcgtggttcgagtccaagccgctgttcggctggaacgtgctcgtgccgcgc
accaaggaacaggccgcctcgctctccgaccaactgcgctcctacggggcggtgcccagc
gaggtgccgaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgccgtc
aagggcctggtcaccgggcgctacgagtggatcgcgttcacatcggtcaacgcggtcaag
gcggtgcgcgagaagttcgaggagtacgggctcgacgcgcgcgccttcgccggcatcaag
gtcgccgcggtcggcgagcagaccgcgaggtcgctggtcgagttcggcgtcaagccggac
ctggtgcccagcggcgagcagtcggcggccgggctcctggaggactggccgccgtacgac
ccggtcttcgacccgatcgaccgcgtcttcctgccgcgggccgacatcgccaccgagacg
ctggtggccggactgatcgagctgggctgggaggtggacgacgtcaccgcgtaccggacg
gtgcgcgcgtcgccgccgccggccgagacccgcgaggccatcaagggcggcggcttcgac
gcggtgctgttcacctcgtcgtcgaccgtgcggaacctcgtcggcatcgcgggcaagccg
cacaatgtcaccgtcatcgcctgcatcggcccggccaccgcgaagaccgcggaggagcac
gggctgcgggtggacgtgctgtcgcccgagccctcggtgcacaagctggccgaggcgctc
gccgagttcggggcggcgcggcgggccgccgccatcgaggccggggacccggtcacgcgc
ccgagcgagcgacggcccggatcgcgtaggagggcacgctcttga
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