Streptomyces californicus: I6J39_26095
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Entry
I6J39_26095 CDS
T07611
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scal
Streptomyces californicus
Pathway
scal00290
Valine, leucine and isoleucine biosynthesis
scal00660
C5-Branched dibasic acid metabolism
scal01100
Metabolic pathways
scal01110
Biosynthesis of secondary metabolites
scal01210
2-Oxocarboxylic acid metabolism
scal01230
Biosynthesis of amino acids
Module
scal_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
I6J39_26095 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
I6J39_26095 (leuC)
Enzymes [BR:
scal01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
I6J39_26095 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
I6J39_26095 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QRV30379
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Position
5976448..5977875
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPDEVTA
KDLILAIIARIGTGGGQGYILEYRGPAIEKLSMEARMTICNMSIEAGARAGMIAPDATTF
DYLRGRDHAPEGEDWDAAVAYWKTLRSDDDAVFDAEVVIDAAELAPFVTWGTNPGQGAPL
SASVPDPASYEDASERHAAEKALEYMGLTAGQPLREINVDTVFVGSCTNGRIEDLRNAAS
VLDGRKVADGVRMLVVPGSVRVALQAVAEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGRLASPADLSDTRTPAGVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggaaaaggtctgggacgaccacgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcg
ttcgacggactgcgccaggccggacggcaggtacgccgcctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcgcgc
gcccagctggagaccctgcgcaagaactgcgcggacttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcccacacctccacccacggcgcgttcggcgcgctg
gcgttcggcatcggcaccagccaggtggagcacgtcctggccacccagacgctgccgctg
gcccgcccgaagaccatggccatcaccgtcgagggcgaactgcccgacgaggtcaccgcg
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggaggccagggctacatc
ctcgaataccgcggccccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgccggcatgatcgccccggacgccaccaccttc
gactacctccggggccgcgaccacgcccccgagggcgaggactgggacgccgccgtcgcg
tactggaagaccctgcgctccgacgacgacgccgtgttcgacgccgaggtcgtcatcgac
gccgccgaactcgccccgttcgtcacctggggcaccaaccccggccagggcgcccccctg
tcggccagcgtccccgatcccgcctcgtacgaggacgcctcggagcgccacgccgccgaa
aaggccctggagtacatggggttgaccgccggccagccgctgcgcgagatcaacgtggac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcaacgccgcctcc
gtgctggacggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgtc
cgggtcgccctccaggccgtcgccgagggcctggacaaggtcttcaccgaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctcgggatgaaccccgaccaactggccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgaggggcggcagggcaagggcggc
cgcacccacctggtctcgccccaggtcgccgcggccaccgcggtgctgggccgtctggcc
tcgcccgccgacctgtccgacacccgtacccccgccggagtgcgatag
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