Streptomyces cavourensis: CVT27_25250
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Entry
CVT27_25250 CDS
T07023
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
scav
Streptomyces cavourensis
Pathway
scav00290
Valine, leucine and isoleucine biosynthesis
scav00660
C5-Branched dibasic acid metabolism
scav01100
Metabolic pathways
scav01110
Biosynthesis of secondary metabolites
scav01210
2-Oxocarboxylic acid metabolism
scav01230
Biosynthesis of amino acids
Module
scav_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
scav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CVT27_25250 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CVT27_25250 (leuC)
Enzymes [BR:
scav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CVT27_25250 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CVT27_25250 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
ATY98405
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Position
5672627..5674054
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPEDVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRDAAPKGADWDAAVAYWKTLRTDDDAVFDAEVVIDAAGLAPFVTWGTNPGQGAPL
SANVPDPASYEDASERNAAEKALEYMGLTAGQPLRDINVDTVFVGSCTNGRIEDLRNAAS
ILDGRKVADGVRMLVVPGSVRVALQAVSEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGRLASPADLSDTRTPAGVA
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctgcgccaggccggacgcccggtgcggcgcctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgcggacccggtctcccgc
gcccagctggagaccctgcgcaagaactgcgcggagttcggcgtacggctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtggtcggcccgcagctcggcctgacccagccc
ggcaccaccgtggtctgcggcgactcccacacctccacgcacggggcgttcggcgcgctg
gcgttcggcatcggcaccagccaggtggagcacgtcctggccacccagacgctgccgctg
gcccgcccgaagaccatggccatcaccgtcgagggcgagctgcccgaggacgtcaccgcc
aaggacctgatcctcgcgatcatcgcccggatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgccccggacgagaccaccttc
gcctatctggagggccgcgacgccgcccccaagggcgcggactgggacgccgccgtggcg
tactggaagaccctgcgcacggacgacgacgcggtgttcgacgccgaggtcgtcatcgac
gccgccgggctggccccgttcgtcacctggggcaccaacccgggccagggcgccccgctc
tccgcgaacgtccccgacccggcatcgtacgaggacgcatcggagcgcaacgccgccgaa
aaggccctggagtacatggggttgaccgccggccagccgctgcgcgacatcaacgtcgac
accgtcttcgtaggttcgtgcaccaacggacgcatcgaggacctgcgcaacgccgcctcg
atcctggacggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctcggtc
cgggtcgcgctccaggccgtctccgaggggctggacaaggtcttcaccgccgccggagcc
gaatggcggcacgcgggttgctcgatgtgcctcggtatgaaccccgaccagctggccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgagggcaggcagggcaagggcggc
cgcacccacctggtctcgccccaggtcgccgccgccaccgccgtgctgggccgtctggcc
tcgcccgccgacctgtccgacacccgtacccccgccggagtcgcatag
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