Saccharomyces cerevisiae (budding yeast): YKR069W
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Entry
YKR069W CDS
T00005
Symbol
MET1, MET20
Name
(RefSeq) uroporphyrinogen-III C-methyltransferase
KO
K00589
uroporphyrin-III C-methyltransferase [EC:
2.1.1.107
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00860
Porphyrin metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
YKR069W (MET1)
Enzymes [BR:
sce01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
YKR069W (MET1)
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Motif
Pfam:
TP_methylase
Sirohm_synth_M
NAD_binding_7
Sirohm_synth_C
Motif
Other DBs
NCBI-GeneID:
853943
NCBI-ProteinID:
NP_012995
SGD:
S000001777
UniProt:
P36150
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Position
XI:571612..573393
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AA seq
593 aa
AA seq
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MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIHSILNAGGNPIVVNPSS
PSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVDRVFVDLPITQSRLCEEIF
WQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVTTNGNGYILANRIKRDIISHL
PPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSLPGFGYGLDEDGWESHKFNKLIR
EFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLEDFETSSSPNKKTKQETVTEGVVPPT
DENIENGTKQLQLSEVKKEEGPKKLGKISLVGSGPGSVSMLTIGALQEIKSADIILADKL
VPQAILDLIPPKTETFIAKKFPGNAERAQQELLAKGLESLDNGLKVVRLKQGDPYIFGRG
GEEFNFFKDHGYIPVVLPGISSSLACTVLAQIPATQRDIADQVLICTGTGRKGALPIIPE
FVESRTTVFLMALHRANVLITGLLKHGWDGDVPAAIVERGSCPDQRVTRTLLKWVPEVVE
EIGSRPPGVLVVGKAVNALVEKDLINFDESRKFVIDEGFREFEVDVDSLFKLY
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atggtacgagacttagtgacattgccttcatcactgcccttgattactgctggttttgct
actgatcaggttcatttgcttattggtacagggtccacggactcagtaagcgtttgtaag
aatagaatccactccattttgaatgctggtggtaatcccatagtagtgaatccctcgtca
ccaagccatactaaacaattacaattggaatttggtaagtttgcaaagttcgaaatagta
gaaagggagtttaggttatctgatttaactactttggggagagttctggtatgcaaggta
gtggatagagtattcgtagatctacccataacacaaagtcgcctatgcgaggagatcttt
tggcaatgccaaaaactgagaattcccataaatacattccacaaaccagagttttctacc
ttcaatatgattcctacgtgggtcgacccaaaaggaagtggtttacaaatctcagttact
acgaatgggaatggatacatcttggcaaacaggataaaaagagatataatatcacactta
cctccaaacatatctgaggtggtgataaacatggggtatttgaaagaccgtattataaac
gaagaccataaggccttgttagaggaaaagtactaccagactgacatgtcattacctgga
tttggctacggcttagatgaggacggttgggagagccataagtttaataagctaattcgt
gaatttgaaatgaccagtagagaacagagacttaagagaaccagatggttatctcagata
atggagtattacccgatgaacaagctgagtgacatcaagttggaagatttcgagacttca
tcttctccaaataaaaagacaaagcaggaaactgtcacagagggtgtagtacctcctacc
gatgaaaatattgaaaacggtacaaaacaactacaattatcggaagtgaaaaaagaggag
ggacctaaaaaactagggaagatttctttagtcggaagtggtccaggctcggtatctatg
ctaacgataggtgcattacaagaaataaagtctgcagatataatactggcagataaactg
gtaccgcaagccattttagatttaatacctccaaaaactgaaaccttcatagccaaaaaa
tttcccggtaatgcagaacgagcacaacaggaattactagctaaaggtttagaatcgttg
gataatggattgaaagtagtccgtttgaagcaaggtgatccgtatatttttggccgtggt
ggcgaggaatttaatttcttcaaagatcacggatatattcctgtggttttaccgggcata
agctcatccctagcttgtactgtattggctcagatacccgctactcaacgtgatatagca
gaccaagtgctcatatgtactgggactgggagaaagggcgctctgcctataattcctgaa
tttgttgaaagcagaaccaccgtctttctaatggcactgcatcgcgccaacgttctgatc
acgggattattgaagcatggctgggatggtgatgtccccgctgcaattgtcgagagagga
tcgtgccctgaccagcgtgttactagaactcttcttaaatgggtaccagaagtcgtggag
gagattggttcaaggccccccggtgtcttggttgtaggcaaggctgtgaatgcattggtt
gaaaaagatctgataaattttgacgaatcaagaaaatttgtcattgatgaaggttttaga
gaatttgaggttgatgtagatagtctatttaagttatactaa
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