Streptomyces chromofuscus: IPT68_26395
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Entry
IPT68_26395 CDS
T07378
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
schf
Streptomyces chromofuscus
Pathway
schf00290
Valine, leucine and isoleucine biosynthesis
schf00660
C5-Branched dibasic acid metabolism
schf01100
Metabolic pathways
schf01110
Biosynthesis of secondary metabolites
schf01210
2-Oxocarboxylic acid metabolism
schf01230
Biosynthesis of amino acids
Module
schf_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
schf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
IPT68_26395 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
IPT68_26395 (leuC)
Enzymes [BR:
schf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
IPT68_26395 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
IPT68_26395 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QOV43259
UniProt:
A0A7M2T548
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Position
5830685..5832115
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLYIDLHLLHEVTSPQAFDGLRKSGRQLRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPDGVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIDAAELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLEAGQPLRSINVDTVFVGSCTNGRIEDLRAAAD
LMRGRKVADGVRMLIVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVETRTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctctacatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctccgcaagagcggccgtcagctgcgccgcctcgacctgaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgcggaccccgtctcccgc
gcccagctggagacgctgcgcaagaactgcgccgagttcggcgtgcgcctgcacccgctg
ggcgacgtcgagcagggcgtcgtccacgtcgtgggcccgcagctgggactgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcacctcgcaggtcgagcacgtgctggccacccagacgctgccgttg
gcccgcccgaagaccatggcgatcacggtcgacggcgagctgcccgacggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaggatcggcaccggcggcggccagggctacatc
ctggaataccgcggctccgccatcgagaagctttcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccacgttc
gcctacctcaagggccgtccgcacgccccggagggcgccgactgggacgccgcggtcgag
tactggaagacgctcaggaccgacgacgacgccgagttcgacgccgaggtcgtcatcgac
gccgccgagctgtcgccgttcgtcacctggggcaccaacccgggtcagggcgcgccgctt
tcggcatccgtccccgaccctgcttcgtacgaagacgcttcggagcgcctcgccgccgaa
aaggccctggagtacatggggttggaggccggtcagccgctgcggtccatcaatgtggac
accgtcttcgtaggctcgtgcaccaacggccgcatcgaggacctgcgcgccgccgccgat
ctgatgcggggccgcaaagtcgccgacggcgtgcggatgctgatcgttccgggctccgcg
cgcgtcggtctgcaggccgtctccgagggtctggacgtggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggccccc
ggtgagcgctcggcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cggacgcacctggtgtcgccgcaggtcgccgccgcgaccgcggtgctggggcacctggcc
tccccggccgacctgtccgacgtcgagacccgtacgcccgctggagtctga
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