Streptomyces collinus: B446_21050
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Entry
B446_21050 CDS
T02787
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sci
Streptomyces collinus
Pathway
sci00860
Porphyrin metabolism
sci01100
Metabolic pathways
sci01110
Biosynthesis of secondary metabolites
sci01120
Microbial metabolism in diverse environments
sci01240
Biosynthesis of cofactors
Module
sci_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sci_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sci00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
B446_21050
Enzymes [BR:
sci01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
B446_21050
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
B446_21050
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AGS71022
UniProt:
S5VKB1
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All DBs
Position
4865626..4867335
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AA seq
569 aa
AA seq
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MSPTAFPAGPEHGHVTFLGAGPGDPGLLTLRAVEALSSADVLVAEHDVLDVIQTHARQGV
SVVRTDADASSVSPPGTGAPQLTVVDGTSTAAAVPSPARDAAHLVMEAARGGRRVVRAVP
GDPGLDTYAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAHGADVRFVDARTAS
GRCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLSVTVAGTTTRQRTWTATLG
TIAQTLKQAKVLPSPDGGRPVIAVVGERSAAAQRDQLSWFESKPLFGWKVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLK
RRAAALEAGDPVTRPSERRPGARRRRSTT
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccgcctttcccgccggtccggaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtggaggcgctgtcgagcgctgac
gtcctggtcgccgagcacgatgtgctcgacgtgatccagacgcacgcccggcagggcgtc
tccgtggtacggacggatgccgacgcctcctcggtctcgccaccgggcacgggcgcgccg
cagctcacggtcgttgacggcacgtcaacagccgctgcggtcccgtctcctgcccgggat
gccgctcatcttgtcatggaggccgcgcggggcggcaggcgggtcgtccgtgcggtgccc
ggggacccgggacttgatacgtacgcggccgaggaaatgctcgcctgcgccgccgccggt
gtgcccttcgaggtggtaccgggtgtggcggccgcggtcggtgtgccggcgtacgccggt
gtgccgctgcgggacgcgcacggcgcggacgtccggttcgtggacgcccgtaccgcctcc
ggccgctgctggacggaggtcggcgcctcggacggcacggtggtcgtgtccacgacgctg
gactcggtcgcggccgcggccggggagctggtgtcggcgggccgcaagccggacaccccg
ctgagtgtcacggtcgccggtacgacgacccggcagcgcacctggacggcgacgctcggc
acgatcgcgcagacgctgaagcaggcgaaggtgctgccgtcgccggacggcggccggccg
gtgatagccgtggtcggtgagcggtccgccgccgcccagcgcgaccagttgtcgtggttc
gagtccaagccgctgttcggctggaaggtgctcgtgccgcggacgaaggagcaggcggcg
tcgctctccgaccagctgcggtcctacggtgccgtgccgcacgaggtcccgacgatcgcc
gtggagccgccgcgcacgccccagcagatggagcgtgccgtcaagggcctggtgaccggc
cgctacgagtggatcgcgttcacctcggtcaacgcggtgaaggcggtccgggagaagttc
gaggagtacggcctcgacgctcgggccttcgcgggcatcaaggtggccgcggtgggcgag
cagaccgcgaaggcgctcgtcgcgttcggtgtgaagccggacctggtgccgagcggcgag
cagtcggccgcgggcctgctggaggactggccgccctacgacccggtgttcgacccgatc
gaccgcgtcttcctgccgcgtgccgacatcgccacggagaccctggtcgccggtctgatc
gagctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcgtcgccgccg
ccggcggacacccgtgaggccatcaagggcggcggtttcgacgcggtgctgttcacgtcg
tcgtcgaccgtccggaacctggtgggtatcgcgggcaagccgcacaacgtgacggtgatc
gcctgtatcggcccggcgacggccaagacggccgaggagcacgggctgcgggtcgacgtg
atggctccggagccgtcggtgcacaagctggccgaggcgctggcggacttcggtctgaag
cgccgggcggccgcgctggaggcgggggaccccgtcacccggccgagcgagcggcggccg
ggggcgcgcaggcgccggtcgacgacctga
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