Streptomyces cinnabarinus: STRCI_004620
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Entry
STRCI_004620 CDS
T08957
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scir
Streptomyces cinnabarinus
Pathway
scir00860
Porphyrin metabolism
scir01100
Metabolic pathways
scir01110
Biosynthesis of secondary metabolites
scir01120
Microbial metabolism in diverse environments
scir01240
Biosynthesis of cofactors
Module
scir_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scir_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scir00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
STRCI_004620
Enzymes [BR:
scir01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
STRCI_004620
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
STRCI_004620
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WAZ23284
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Position
5102798..5104486
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AA seq
562 aa
AA seq
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MSPTTLPAGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRVHARTGV
AVVHTDPSSEPGTPQLAVVDGASTTAGAPAVRDAAHLVMEAARGGRRVVRAVSGDPGLDT
YAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTASDRCWTEV
GASDGTVVVSTTLDSVGAAAGELVAAGRKPDTPMTVTVAGTTTRQRTWTATLGTIAQTLK
QAKVLPSPEGGRPVIAVVGERSATAQREQLSWFESKPLFGWRVLVPRTKEQAASLSDQLR
SYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDA
RAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPR
ADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSSSTVRNL
VGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALANFGAKRRDAAVE
AGDPVTRPSERRPGARRRRTTT
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgccggcctcgaacacgggcacgtcaccttcctgggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtcgaggcgctggcgaacgcggat
gttctcgtcgccgagcacgaggtgctcgacgtcgtacgcgtccacgccaggacaggcgtc
gccgtcgtgcacacggacccttcgtcggagccgggcacacctcagctagcagttgttgac
ggtgcgtcaacaaccgctggagcacccgctgtgcgggatgcggcacatcttgtcatggag
gccgcgcggggcggcaggcgggtcgtgcgtgcggtgtccggggaccccgggctcgacacg
tacgccgccgaggagatgctggcgtgcgccgccgccggggtgcctttcgaggtggtcccc
ggtgtcgcggccgcggtcggcgtgcccgcgtacgccggtgtgccgctgcgcgacgcgcag
ggtgcggacgtgcggttcgtggacgcgcgcacggcgtcggaccggtgctggacggaggtc
ggtgcctcggacgggacggtggtcgtctccacgacgctcgactccgtcggcgccgcggcc
ggtgagctggtggccgccggccgtaagccggacaccccgatgacggtgacggtcgccggt
acgaccacgcggcagcggacctggaccgcgacgctcggcaccatcgcgcagacgctgaag
caggccaaggtgctgccctcgcccgaaggcgggcgaccggtgatagccgtggtcggcgag
cggtccgcgacggctcagcgcgagcagctgtcgtggttcgagtccaagccgctcttcggg
tggcgggtgctggtgccgcgcaccaaggagcaggcggcttcgctctccgaccagcttcgg
tcgtacggggcggtcccgcacgaggtgccgacgatcgccgtcgagccgccgcgcacgccg
cagcagatggagcgggcggtcaagggcctggtcacgggccgctacgagtggatcgccttc
acctcggtgaacgcggtcaaggcggtgcgcgagaagttcgaggagtacgggctcgacgct
cgggcgttcgccggtatcaaggtcgccgcggtgggcgagcagacggcgaaggcgctgatc
gcgttcggtgtgaagccggacctcgtgccctcgggcgagcagtcggccgcgggtctgctg
gaggactggccgccgtacgaccccgtcttcgatccgatcgaccgggtgttcctgccgcgg
gcggacatcgccacggagacgctggtcgccgggctgatcgagctcgggtgggaggtggac
gacgtcacggcctaccggaccgtgcgggcgtcgccgccgccggcggagacccgggaggcg
atcaaggggggtggcttcgacgccgttctcttcacctcgtcgtccacggtgcggaacctg
gtgggtatcgccggcaagccgcacaacgtgacggtgatcgcctgtatcggtcccgccacc
gcgaagaccgccgaggagcacgggctgcgggtcgatgtgatggctccggagccgtccgtg
cacaagctggcggaggcgctggcgaacttcggcgcgaagcggcgggacgcggcggtggag
gccggggatccggtcacccggccgagcgagcgtcggccgggcgcgcggaggcgtcggacc
acgacgtga
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