Streptomyces coelicolor: SCO3317
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Entry
SCO3317 CDS
T00085
Symbol
SCE68.15c
Name
(RefSeq) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00860
Porphyrin metabolism
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
sco01120
Microbial metabolism in diverse environments
sco01240
Biosynthesis of cofactors
Module
sco_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sco_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SCO3317 (SCE68.15c)
Enzymes [BR:
sco01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SCO3317 (SCE68.15c)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SCO3317 (SCE68.15c)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
RodZ_C
Motif
Other DBs
NCBI-GeneID:
1098751
Kitasato:
SCO3317
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Position
complement(3668023..3669720)
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AA seq
565 aa
AA seq
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MSPTTLPAGPEHGHVTFLGAGPGDPGLLTLRAVEALAHADVLVAEHEVLDVVRTHAKQGV
SEVHTDADPSDPGTGAPQLTVVDGASTTFGAPAVRDAAHLVMEAARGGRRVVRAVTGDPG
LDAYAAEEMLACAAAGVPFEVVPGIANAVGVPAYAGVPLRDAEGADVRFVDARTASDRCW
TEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTVAQ
TLKQAKVLPSPDGGRPVIAVVGERSSAARRDQLSWFESKPLFGWKVLVPRTKEQAASLSD
QLRSYGAVPSEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYG
LDARAFAGIKVAAVGEQTANALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVF
LPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPATTREAIKGGGFDAVLFTSSSTV
RNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMSPEPSVTKLAEALADFGLRRRAA
ALEAGDPVTRPSERRPGSRRRRSST
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgccggtcctgaacacgggcacgtcaccttcctcggtgcc
ggacccggagatccgggactgctgactctgcgcgccgtcgaggcgctggcgcacgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtacgcacgcacgcgaagcagggcgtg
tcggaagtgcacacggatgccgatccgtcggatccgggcacaggcgcgccccagctgacg
gtagttgacggtgcgtcaacgaccttcggcgcccccgctgtgcgggatgccgcacatctt
gtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcggtgaccggggatcccggg
ctcgacgcgtacgccgccgaggagatgctggcgtgcgccgcggccggggtgcccttcgag
gtcgtcccgggcattgcgaacgccgtcggcgtgcccgcgtacgccggtgtgccgctgcgg
gacgcggagggcgcggacgtgcgcttcgtggacgcccgtacggcctcggaccgctgctgg
accgaggtgggcgcctccgacggcacggtggtggtgtcgacgacgctcgactcggtggcc
gcggcggccggtgagctggtctcggccggccgcaagccggacaccccgctgacggtgacc
atcgccggtacgaccacgcggcagcgcacctggacggcgacgctgggcacggtcgcgcag
acgctgaagcaggcgaaggtgctgccgtccccggacggcggccgcccggtgatagccgtg
gtcggcgagcgcagctccgccgcccggcgcgaccagctgtcgtggttcgagtccaagccg
ctgttcggctggaaggtcctcgtcccgcgcacgaaggagcaggcggcttcgctctccgac
cagctgcggtcctacggggccgtcccgagcgaggttccgaccatcgcggtggagccgccg
cgcaccccgcagcagatggagcgggcggtcaagggcctggtgacgggccgctacgagtgg
atcgcgttcacgtcggtcaacgcggtcaaggcggtccgtgagaagttcgaggagtacggg
ctggacgcccgcgccttcgcgggcatcaaggtcgcggcggtgggcgagcagacggccaac
gcgctgatcgccttcggcgtcaagccggacctggtcccgagcggcgagcagtcggccgcc
ggtctcctggaggactggccgccctacgacccggtcttcgacccgatcgaccgtgtcttc
ctgccccgcgccgacatcgccacggagaccctggtcgccgggctgatcgagctgggctgg
gaggtcgacgacgtcaccgcctaccgcacggtgcgcgcctcgccgccgccggccacgacc
cgggaggccatcaagggcggcggcttcgacgcggtgctcttcacgtcgtcctccacggtc
cgcaacctcgtcggcatcgcgggcaagccgcacaacgtcacggtgatcgcctgcatcggc
ccggcgacggccaagacggccgaggaacacgggctgcgcgtcgacgtgatgtcccccgag
ccgtccgtcaccaagctggcggaggccctggccgacttcggcctgcggcgccgggcggcg
gccctggaggcgggggatccggtgacgcggccgagcgaacggcggccggggtcgcggaga
cggcggtcgtcgacctga
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