Streptomyces sp. CdTB01: AS200_21385
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Entry
AS200_21385 CDS
T04240
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scx
Streptomyces sp. CdTB01
Pathway
scx00860
Porphyrin metabolism
scx01100
Metabolic pathways
scx01110
Biosynthesis of secondary metabolites
scx01120
Microbial metabolism in diverse environments
scx01240
Biosynthesis of cofactors
Module
scx_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AS200_21385
Enzymes [BR:
scx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
AS200_21385
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AS200_21385
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ALV34323
UniProt:
A0A0U3PZQ9
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Position
complement(4789557..4791263)
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AA seq
568 aa
AA seq
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MSPTTLPTGLDHGHVTFLGAGPGDPGLLTLRAVEALATADVLVAEGDVLDVVRQHARHGV
AEVHTDGGPSSDPVPGTGTPQLAVVDAASTTAGAPAVRDAAHLVMEAARGGRRVVRAVSG
DPGLDAYAAEEMLACVRAGVPFEVVPGVAAAVGVPAYAGVPLRDAEGADVRFVDARTASD
RCWSEVGASDGTVVVSTTLDAVGAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPDGGRPVIVVVGERSAAAQRDQLSWFENKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTARALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGLRR
RAAALESGDAVTRPSERRPGARRRRTTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccaccggcctcgatcacgggcacgtcaccttcctgggcgcc
ggacccggggatccgggactgctgactctgcgcgccgtcgaggcgctcgcgaccgcggac
gtcctcgtcgccgagggcgacgtgctcgacgtggtgcgccagcacgcccgacacggcgtc
gccgaggtgcacacggacgggggtccttcgtcggacccggttccgggcacgggcacacct
cagctggcggttgttgacgcagcgtcaacaaccgctggggcccccgcggtacgggatgcc
gcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtccgtgcggtgtccggt
gaccccggcctggacgcttacgccgccgaggagatgctcgcctgcgtccgcgccggtgtg
cccttcgaggtcgtgccgggtgtcgcggcggccgtgggcgtgcccgcgtacgccggtgtc
ccgctgcgcgacgccgagggcgcggacgtgcggttcgtggacgcccgtaccgcctccgac
cggtgctggagcgaggtcggcgcctccgacgggacggtggtcgtctcgacgaccctggac
gccgtgggcgcggccgccggcgaactggtgtccgcaggacgcaagcccgacaccccgatg
acggtgacggtggccggtacgaccacccggcagcggacctggacggcgacgctcggcacc
atcgcgcagacgctgaagcaggcgaaggtgctgccctcgccggacggcggccggccggtg
atagtcgtggtcggcgagcgttccgccgccgcccagcgcgaccagctgtcgtggttcgag
aacaagccgctgttcggctggaaggtcctcgtgccgcgcacgaaggagcaggcggcctcg
ctctccgaccagctgcgctcctacggcgccgtgccgcacgaggtcccgacgatcgccgtc
gagccgccgcgcacgccccagcagatggagcgggccgtgaaggggctcgtcaccggccgg
tacgagtggatcgccttcacgtccgtcaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggctcgacgcgcgcgccttcgcggggatcaaggtcgccgcggtgggcgagcag
accgccagggcgctggtcgccttcggcgtgaagccggacctggtgccgagcggggagcag
tccgccgccgggctcctggaggactggccgccgtacgacccggtcttcgacccgatcgac
cgggtgttcctgccgcgtgcggacatcgccacggagaccctcgtggccgggctcatcgag
ctgggctgggaggtcgacgacgtcacggcgtaccggaccgtgcgggcctcgccgccgccg
gcggagacccgcgaggcgatcaagggcggtggcttcgacgccgtgctgttcacctcgtcc
tcgaccgtgcgcaacctggtcgggatcgccgggaagccgcacaacgtgaccgtcatcgcg
tgcatcgggcccgccacggcgaagaccgccgaggagcacgggctgcgggtggacgtgatg
gctcccgagccgtccgtgcacaagctggcggaggcgctggccgacttcgggctgcggcgg
cgggccgcggcgctggagagcggggacgcggtgacgcggccgagcgagcggaggccgggg
gcgcggaggcggcggacgaccacgtga
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