Streptomyces cyaneochromogenes: EJ357_26495
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Entry
EJ357_26495 CDS
T06811
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
scya
Streptomyces cyaneochromogenes
Pathway
scya00860
Porphyrin metabolism
scya01100
Metabolic pathways
scya01110
Biosynthesis of secondary metabolites
scya01120
Microbial metabolism in diverse environments
scya01240
Biosynthesis of cofactors
Module
scya_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
scya_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
scya00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
EJ357_26495
Enzymes [BR:
scya01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
EJ357_26495
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
EJ357_26495
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AZQ36554
UniProt:
A0A3Q9EPP2
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Position
5823240..5824946
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AA seq
568 aa
AA seq
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MSPTTLPAGLEHGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHEVLDVVRQHARQGV
AEVHTDTGPESDPVPGTGTPQLAVVDGASTTAGLPAVRDAAHLVMEASRGGRRVVRAVSG
DPGLDAYAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDAQGADVRFVDARTASD
RCWTEVGASDGTVVVSTTLDAVGAAAGELVSAGRKPDTPMTVTVAGTTTRQRTWSATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDQLSWFESKPLFGWRVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGMRR
RAAAVEAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgccggccttgaacacgggcacgtcaccttcctcggtgcc
ggacccggggatccggggctactgactctgcgcgccgtcgaggcgctggcgaacgcggac
gtactcgtcgccgagcacgaggtgctcgacgtcgtacgccagcacgccagacaaggcgtg
gccgaagtgcacacggacacgggtcctgaatcggaccccgtcccgggcacaggcacgcct
cagctggcggttgttgacggcgcgtcaacaaccgctgggctacccgcggtgcgggatgcc
gcacatcttgtcatggaggcctcgcggggcggcaggcgggtcgtgcgtgccgtgtccggg
gatcccgggctcgacgcgtacgccgccgaggagatgctggcgtgtgccgcggcgggcgtg
cccttcgaggtcgtgccgggtgtggcggcggccgtgggcgtgcccgcgtacgccggcgtg
ccgctgcgagacgcgcagggcgcggacgttcggttcgtggacgcgcggacggcgtcggac
cggtgctggaccgaggtgggtgcctcggacgggaccgtcgtggtttcgacgacgctcgac
gctgtgggtgcggctgccggtgagctggtgtcggcggggcgtaagcctgatacgccgatg
acggtgaccgtcgccggtacgaccacgcggcagcggacctggagcgcgaccctggggacc
atcgcccagacgctgaagcaggccaaggtgctgccctcgccggagggcgggcggccggtg
atagccgtggtcggtgagcggtctgccgccgcgcagcgcgaccagttgtcgtggttcgag
tccaagccgctcttcgggtggcgggtgctcgtgccgcgtacgaaggagcaggcggcttcg
ctctccgaccagttgcggtcgtacggggccgtgccgcacgaggtgccgacgatcgccgtc
gagccgccgcggacgcctcagcagatggagcgggcggtcaaggggctggtgaccgggcgg
tacgagtggatcgctttcacctccgtgaacgcggtcaaggccgtgcgggagaagttcgag
gagtacgggcttgatgctcgggcgtttgccgggatcaaggtcgccgcggtgggggagcag
acggcgaaggcgctggttgcctttggtgtgaagccggatctggtgccgagtggggagcag
tcggctgcggggttgttggaggactggcctccgtacgacccggtgttcgatcccattgac
cgggtgttcctgcctcgggcggacatcgccacggagacgctggtcgcgggtctgatcgag
ctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcctcgccgccgccg
gcggagacccgtgaggcgatcaaggggggtggcttcgatgccgttctcttcacgtcgtcg
tcgaccgtgcggaatctggtggggatcgccgggaagccgcacaacgtgacggtgatcgcc
tgtatcggtcctgccacggcgaagaccgctgaggagcatgggctccgggtggatgtgatg
gctccggagccgtccgtgcacaagttggccgaggcgcttgccgagttcgggatgcggcgg
cgggctgcggctgtggaggctggggatccggtcactcggccgagtgagcggcggccgggg
gctcggcggaggcggtctactacgtag
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