Streptomyces dangxiongensis: D9753_15235
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Entry
D9753_15235 CDS
T08044
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sdd
Streptomyces dangxiongensis
Pathway
sdd00860
Porphyrin metabolism
sdd01100
Metabolic pathways
sdd01110
Biosynthesis of secondary metabolites
sdd01120
Microbial metabolism in diverse environments
sdd01240
Biosynthesis of cofactors
Module
sdd_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sdd_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sdd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
D9753_15235
Enzymes [BR:
sdd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
D9753_15235
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
D9753_15235
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AYN40048
UniProt:
A0A3G2JCK6
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Position
complement(3434183..3435892)
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AA seq
569 aa
AA seq
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MSPTALTAGLEHGHVTFLGAGPGDPGLLTLRAVEALSHADVLVAEPEVLDVIRTHARQSV
SVVETNAEPSSVSPPGTGTPQLTVVDGTSTATAVPSPARDAVHLVMEAARGGRRVVRAVP
GDPGLDTYAAEEMLACAAAGVPFEVVPGVAAVVGVPAYAGVPLRDAQGADVRFVDARTAS
DRCWTEVGASDGTVVVSTTLDSVAVAAGELVAAGRKPDTPLTVTIAGTTTRQRTWTATLG
TIAQTLKQAKVLPSPDGGRPVIAVVGERSAAARRDQLSWFESKPLFGWKVLVPRTKEQAA
SLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKF
EEYGLDARAFAGIKVAAVGEQTAKALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPI
DRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTS
SSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGMR
RRAAALEAGDPVTRPSERRPGARRRRTTT
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgagccccaccgcccttaccgccggcctggaacacggtcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgactctgcgcgccgtggaggcgctgtcgcacgcggac
gtcctggtcgccgagcccgaggtgctcgacgtgatccggacgcacgcgcggcaaagtgtc
tcggtcgtggaaacgaacgcggaaccctcctcggtctcaccgccgggcacgggcacgccg
cagctcacggtcgttgacggcacgtcaacagcgactgcggtcccgtctcctgcccgggat
gccgtccatcttgtcatggaggccgcacggggcggcaggcgggtcgtccgtgcggtgccc
ggggacccgggacttgatacgtacgccgcggaggaaatgctcgcctgcgccgccgccggg
gtgcccttcgaggtcgtccccggtgtcgcggccgtcgtcggcgtgcccgcgtacgccggc
gtgccgctgcgggacgcccagggcgcggacgtccggttcgtggacgcccggaccgcctcc
gaccgctgctggacggaggtgggcgcctcggacggcacggtggtcgtctccacgaccctg
gactccgtggccgtggcggccggcgagctggtcgcggcgggccgcaagccggacaccccg
ctgacggtgacgatcgccggtacgacgacccggcagcggacgtggacggcgacgctcggc
acgatcgcgcagacgctgaagcaggcgaaggtgctgccgtcgccggacggcggccggccg
gtgatagccgtggtcggtgagcgttccgccgccgcccggcgcgaccaactgtcctggttc
gagtccaagccgctgttcggctggaaggtgctcgtgccgcggacgaaggagcaggcggcg
tcgctctccgaccagctccggtcctacggcgccgtgccgcacgaggtgccgacgatcgcc
gtcgagcccccgcgcacgcctcagcagatggaacgtgccgtcaagggtctggtgaccgga
cggtacgagtggatcgccttcacgagcgtgaacgccgtcaaggccgtccgggagaagttc
gaggagtacgggctcgacgcgcgggccttcgcgggcatcaaggtggccgccgtgggcgag
cagaccgccaaggcgctggtcgccttcggcgtgaagccggacctggtgccgagcggtgag
cagtcggcggcgggtctgctggaggactggccgccgtacgacccggtgttcgacccgatc
gaccgggtgttcctgccgcgggcggacatcgccacggagacgctggtggccgggctgatc
gagctgggctgggaggtcgacgacgtcacggcctaccggaccgtgcgggcgtcgccgccg
ccggcggagacccgcgaggcgatcaagggcggtggcttcgacgcggtgctgttcacgtcg
tcgtccaccgtgcggaacctggtgggcatcgccggcaagccgcacaacgtcaccgtgatc
gcgtgcatcggtccggccacggccaagaccgccgaggagcacgggctgcgggtggacgtg
atggctccggagccgtcggtccacaagctggccgaggcgctggcggagttcgggatgcgc
cgtcgcgcggcggccctggaggccggcgacccggtcacccggcccagcgagcggcgaccg
ggagcgcgcaggcgtcgtacgacgacgtga
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