Streptomyces durmitorensis: M4V62_19560
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Entry
M4V62_19560 CDS
T08503
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00860
Porphyrin metabolism
sdur01100
Metabolic pathways
sdur01110
Biosynthesis of secondary metabolites
sdur01120
Microbial metabolism in diverse environments
sdur01240
Biosynthesis of cofactors
Module
sdur_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sdur_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
M4V62_19560
Enzymes [BR:
sdur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
M4V62_19560
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
M4V62_19560
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UQT57122
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Position
complement(4361337..4362995)
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AA seq
552 aa
AA seq
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MSPTSNLPGLPAHGHVTFLGAGPGDPGLLTLRAVEALARADVLIAEPDVLDVVSAHARGG
VDTPQPGTVDDASAITEASSLRAATNLVMEAARGGKRVVRAVSGDVGLDTYAAEEMLACA
AEGIPFEVVPGIAAAVGVPAYAGVPLRDAQGTDVRFVDARTASDRCWSEVGASDGTVVVS
TSLDSVAAAAGELVSSGRKPDTPMTVTIAGTTTRQRTWTATLGTIAQVLKQAKVLPSPDG
GQPVIAVVGERSAAAQRDQLSWFESKPLFGWRVLVPRTKEQAASLSDQLSSYGAVPHEVP
TIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAA
VGEQTAAALVAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVA
GLIDLGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNV
TVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFGTRRRLAALEAGDPVTRPSE
RRPGSRRRRTAP
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccacctcgaaccttcccggccttcccgcacacgggcacgtcaccttcctgggt
gccggacccggagatccgggactacttacgctgcgcgccgtagaggcgctggcccgagcg
gacgtgctgatcgccgagcccgatgtgctcgacgtcgtctccgcgcatgccaggggaggt
gtggacacacctcagccagggacagttgacgacgcgtcagcgatcaccgaagcgtcctcg
ttgcgagccgccaccaatcttgtcatggaggcagcacgcggcggcaagcgggtcgtacgt
gccgtcagcggcgacgtcggcctcgacacgtacgccgcggaggagatgctcgcctgcgcc
gccgagggcattcccttcgaagtcgtgcccggcatcgcggcggcggtcggtgtacccgcc
tacgcgggtgttccgctgcgcgacgcccagggcacggacgtgcgcttcgtcgacgcgcgc
accgcgtccgaccgctgctggagcgaggtgggggcatcggacgggaccgtggtcgtgtcg
acctccctggactccgtggccgcggccgccggtgaactggtgtcgtccggccgcaagccg
gacaccccgatgacggtgacgatcgccggtacgacgacgcgtcagcgcacgtggacggcg
accctcggcacgatcgcgcaggtcctcaagcaggcgaaggtgctgccttcgcccgacggc
gggcagcccgtcatagccgtggtcggtgagcggtccgccgctgcccagcgtgaccagctg
tcgtggttcgagtcgaagccgctcttcgggtggcgggtgctcgtgccgcgtacgaaggag
caggcggcctcgctctccgaccagctgagctcctacggtgcggtgccgcacgaggtgccg
accatcgccgtggagccgccccgcacgccccagcagatggagcgcgcggtcaaggggctc
gtcacgggtcgctacgagtggatcgccttcaccagcgtcaacgccgtcaaggcggtgcgt
gagaagttcgaggagtacgggctcgacgcgcgcgccttcgccgggatcaaggtcgcggcg
gtgggcgagcagacggctgccgcgctcgtcgccttcggcgtgaagcccgacctggtgccc
agcggtgagcagtcggccgcgggtctcctggaggactggccgccgtacgacccggtcttc
gacccgatcgaccgcgtcttcctgccgcgggccgacatcgccacggagacgctggtcgcc
gggctcatcgacctcgggtgggaggtcgacgacgtcaccgcctaccggacggtgcgcgcg
tcgccgcccccggcggacacgcgtgaggcgatcaagggcggcggcttcgacgccgtgctc
ttcacgtcgtcgagcacggtgcggaacctggtcggcatcgccggcaagccgcacaacgtc
accgtcatcgcctgcatcggtcccgccaccgccaagacggcggaggagcacgggctccgg
gtggacgtgatggctccggagccttccgtccacaagctggccgaggcccttgccgagttc
ggcacgcggcgtcgccttgccgcgctggaggcgggggaccccgtcacccggcccagcgag
cggcggccgggttcccgtaggcggcgtacggcgccgtag
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